Results 131 to 140 of about 175,563 (355)

A comprehensive approach to lifestyle intervention based on a calorie-restricted diet ameliorates liver fat in overweight/obese patients with NAFLD: a multicenter randomized controlled trial in China

Nutrix Journal
Background Nonalcoholic fatty liver disease (NAFLD) is a globally increasing health epidemic. Lifestyle intervention is recommended as the main therapy for NAFLD. However, the optimal approach is still unclear. This study aimed to evaluate the effects of
Zhong Liu, Piaopiao Jin, Yuping Liu, Zhimian Zhang, Xiangming Wu, Min Weng, Suyan Cao, Yan Wang, Chang Zeng, Rui Yang, Chenbing Liu, Ping Sun, Cuihuan Tian, Nan Li, Qiang Zeng   +14 more
semanticscholar   +1 more source

Calorie or Carbohydrate Restriction? The Ketogenic Diet as Another Option for Supportive Cancer Treatment [PDF]

The Oncologist, 2013
The author agrees with Champ et al. that calorie reduction (CR) is a good supportive intervention for patients undergoing radiotherapy or chemotherapy. However, for those with cachexia or for those who are at risk for cachexia, CR may be problematic. Additionally, less food consumed means fewer nutrients.
openaire   +3 more sources

Cytosolic Phosphoenoylpyruvate Carboxykinase Deficiency: Clinical, Biochemical, and Genetic Features of Five Non‐Finnish Patients

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cytosolic phosphoenoylpyruvate carboxykinase (PEPCK‐C) is an essential, rate‐limiting enzyme in the gluconeogenesis pathway. PEPCK‐C deficiency presents with hypoglycaemia, hyperlactataemia and hepatopathy, and was first reported in association with bi‐allelic PCK1 variants in 2014.
Isaac Bernhardt, Polona Le Quesne Stabej, Claire Hart, Mark De Hora, Sarah Hulley, Mark Anderson, Harry G. Leitch, Hugh Lemonde, Bryony Ryder, James Davison   +9 more
wiley   +1 more source

Establishment of a novel cynomolgus monkey model of hyperuricemia

Animal Models and Experimental Medicine, EarlyView.
We established a novel hyperuricemia model in cynomolgus monkeys (A) via oral administration of potassium oxonate, hydrochlorothiazide, and adenine mixed in fruits and vegetables. This model (B) targets uric acid synthesis and enzymatic degradation, and (C) regulates renal and intestinal excretion, thereby stably elevating serum uric acid and serving ...
Ji‐Wei Wang, Le Zhang, Can Yang, Guan‐Cong Luo, Rui‐Chang Liu, Yan‐Jun Xu, Sheng Cheng, Wen‐Yu Jiang, Richard Ward, Yang Yang, Cheng Xiang, Shu An, Tian‐Rui Xu   +12 more
wiley   +1 more source

Guinea pigs: A suitable animal model to study lipoprotein metabolism, atherosclerosis and inflammation

Nutrition & Metabolism, 2006
Numerous animal models have been used to study diet effects on cholesterol and lipoprotein metabolism. However, most of those models differ from humans in the plasma distribution of cholesterol and in the processing of lipoproteins in the plasma ...
Volek Jeff S, Fernandez Maria
doaj   +1 more source

Exploring the acceptability of, and adherence to a carbohydrate-restricted diet as self-reported by women aged 40-55 years [PDF]

, 2018
Julia Mcphee, Caryn Zinn, Melody Smith, W Brown, L Bryson, J Byles, A Dobson, C Lee, G Mishra, M Carr, A Ferland, M-L Chteau-Degat, T Hernandez, R Eckel, S Davis, C Castelo-Branco, P Chedraui, M Lumsden, R Nappi, D Shah, T Hu, K Mills, L Yao, K Demanelis, M Eloustaz, W Yancy, M Dansinger, J Gleason, J Griffith, H Selker, E Schaefer, C Gardner, A Kiazand, S Alhassan, S Kim, R Stafford, R Balise, L Stern, N Iqbal, P Seshadri, K Chicano, D Daily, J Mcgrory, C Forsythe, S Phinney, M Fernandez, E Quann, R Wood, D Bibus, A Mcclain, J Otten, E Hekler, C Gardner, A Ammerman, C Lindquist, K Lohr, J Hersey, A Palmeira, P Teixeira, T Branco, S Martins, C Minderico, J Barata, J Elder, T Schmid, P Dower, S Hedlund, R Levy, E Finch, M Crowell, N Talley, R Jeffery, I Greenberg, M Stampfer, D Schwarzfuchs, I Shai, G Mullins, C Hallam, I Broom, S Shacham, S Alhassan, S Kim, A Bersamin, A King, C Gardner, S Klein, N Mclean, S Griffin, K Toney, W Hardeman, A Gorin, T Powers, R Koestner, R Wing, H Raynor, A Gorin, H Raynor, J Fava, K Maguire, E Robichaud   +99 more
openalex   +1 more source

The complexity of dementia development and its comorbidities: The collaborative cross‐mouse population for multivarious tasks approach

Animal Models and Experimental Medicine, EarlyView.
The increasing prevalence of dementia and related neurodegenerative diseases—including Alzheimer's disease, Parkinson's disease, multiple sclerosis, and amyotrophic lateral sclerosis—poses a growing public health challenge. These conditions have traditionally been studied as isolated central nervous system disorders, but emerging evidence points to ...
Osayd Zohud, Iqbal M. Lone, Kareem Midlej, Fuad A. Iraqi   +3 more
wiley   +1 more source

Evidence for a Lean Mass Hyperresponder Phenotype Is Lacking with Increases in LDL Cholesterol of Clinical Significance in All Categories of Response to a Carbohydrate-Restricted Diet. [PDF]

Curr Dev Nutr, 2022
Moore JM, Diefenbach D, Nadendla M, Hiebert N.   +3 more
europepmc   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Effect of feeding fermentable fibrerich feedstuffs lupin and chicory prior to slaughter with special emphasis on the effect on chemical boar taint in organic entire male and female pigs and technological meat quality [PDF]

, 2007
Boar taint is an off-flavour of pork caused primarily by skatole and, androstenone. Pig off-odour and flavour mostly caused by higher skatole concentrations in backfat.
Hansen, Laurits Lydehøj, Hansen-Møller, Jens, Henckel, Poul, Jensen, Jens Askov, Syriopoulos, Kostas   +4 more
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