Results 311 to 320 of about 1,376,566 (406)

Alistipes senegalensis is Critically Involved in Gut Barrier Repair Mediated by Panax Ginseng Neutral Polysaccharides in Aged Mice

open access: yesAdvanced Science, EarlyView.
An integral functional axis through which GPN and functional metabolites of Alistipes senegalensis can hydrolyze tryptophan into indoles. Furthermore, the Alistipes senegalensis‐indole‐AhR pathway is found to be associated with increased expression of tight junction‐associated proteins and activation of gut stem cells.
Dandan Wang   +10 more
wiley   +1 more source

Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia

open access: yesAdvanced Science, EarlyView.
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji   +12 more
wiley   +1 more source

JA‐Mediated Regulation of Amino Acid Homeostasis Adjusts Metabolic Flux and Enhances Spider Mite Tolerance via the SlJAZ8‐SlWRKY57‐SlAVT6s Module in Tomato

open access: yesAdvanced Science, EarlyView.
This study elucidates a novel SlJAZ8‐SlWRKY57‐SlAVT6A/SlAVT6B module that effectively channels metabolic flux from primary to secondary metabolism, impacting plant growth, development, and resistance. Two novel vacuolar amino acid exporters, SlAVT6A and SlAVT6B, fine‐tunes trichomes, terpenes, and gibberellins, bolstering spider mite resistance.
Yingchen Hao   +11 more
wiley   +1 more source

Dietary carbohydrate intake and health-related outcomes: a protocol for the evidence evaluation methodology for the new guideline on dietary carbohydrate intake of the German nutrition society. [PDF]

open access: yesEur J Nutr
Schlesinger S   +9 more
europepmc   +1 more source

Maximizing Efficacy of Cancer Nanovaccines and Immune Cells Landscape in Responders and Non‐Responders to Immunotherapy

open access: yesAdvanced Science, EarlyView.
To maximize the efficacy of cancer vaccines, adjuvants, collection, lysis, purification, oxidation, loading sites, and sizes, etc., are investigated. The optimized cancer nanovaccines loading whole tumor antigens can cure all or most tumor‐bearing mice in multiple mouse cancer models.
Xiangxiang Xu   +13 more
wiley   +1 more source

Transcriptome‐Wide Association Uncovers LncRNAs Controlling Seed Weight in Soybean

open access: yesAdvanced Science, EarlyView.
This study employs transcriptome‐wide association studies (TWAS) to identify 201 long non‐coding RNAs (lncRNAs) associated with seed weight. Expression quantitative trait locus (eQTL) analysis reveals dynamic and static regulatory variants controlling lncRNA expression across development.
Xiang Wang   +8 more
wiley   +1 more source

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