Results 51 to 60 of about 853,705 (361)

Metabolic Engineering of Saccharomyces cerevisiae for Efficient Retinol Synthesis

Journal of Fungi, 2023
Retinol, the main active form of vitamin A, plays a role in maintaining vision, immune function, growth, and development. It also inhibits tumor growth and alleviates anemia.
Xuan Wang, Xianhao Xu, Jiaheng Liu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu   +7 more
doaj   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source

Differential regulation of the Epr3 receptor coordinates membrane-restricted rhizobial colonization of root nodule primordia

Nature Communications, 2017
TheLotus japonicus LysM receptor kinase EPR3 perceives rhizobial exopolysaccharides to initiate infection of the root epidermis. Here the authors show that EPR3 also mediates infection thread progression in the root cortex and show that key transcription
Yasuyuki Kawaharada, Mette W. Nielsen, Simon Kelly, Euan K. James, Kasper R. Andersen, Sheena R. Rasmussen, Winnie Füchtbauer, Lene H. Madsen, Anne B. Heckmann, Simona Radutoiu, Jens Stougaard   +10 more
doaj   +1 more source

B4GAT1 is the priming enzyme for the LARGE-dependent functional glycosylation of α-dystroglycan

eLife, 2014
Recent studies demonstrated that mutations in B3GNT1, an enzyme proposed to be involved in poly-N-acetyllactosamine synthesis, were causal for congenital muscular dystrophy with hypoglycosylation of α-dystroglycan (secondary dystroglycanopathies).
Jeremy L Praissman, David H Live, Shuo Wang, Annapoorani Ramiah, Zoeisha S Chinoy, Geert-Jan Boons, Kelley W Moremen, Lance Wells   +7 more
doaj   +1 more source

Dietary carbohydrate restriction improves metabolic syndrome independent of weight loss.

JCI Insight, 2019
BACKGROUNDMetabolic syndrome (MetS) is highly correlated with obesity and cardiovascular risk, but the importance of dietary carbohydrate independent of weight loss in MetS treatment remains controversial.
Parker N. Hyde, Teryn N Sapper, Christopher D. Crabtree, Richard A. LaFountain, Madison L Bowling, Alex Buga, Brandon Fell, F. McSwiney, Ryan M. Dickerson, Vincent J. Miller, D. Scandling, O. Simonetti, S. Phinney, W. Kraemer, Sarah King, R. Krauss, J. Volek   +16 more
semanticscholar   +1 more source

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

FEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling, Kodi Hunter, Celest W. S. Tay, Nicola T. Wood, Philip Cohen   +4 more
wiley   +1 more source

Changes of starch during microwave treatment of rice

Czech Journal of Food Sciences, 2003
The properties of rice after microwave irradiation were evaluated by means of amylograph and enzymic determination of the total and the damaged starch. The content of the total starch was not affected by the immediate energy output used for irradiation ...
J. Pinkrová, B. Hubáčková, P. Kadlec, J. Příhoda, Z. Bubník   +4 more
doaj   +1 more source

ON CARBOHYDRATE METABOLISM. [PDF]

Journal of the American Chemical Society, 1906
n ...
openaire   +2 more sources

Effects of a low carbohydrate diet on energy expenditure during weight loss maintenance: randomized trial

British medical journal, 2018
Objective To determine the effects of diets varying in carbohydrate to fat ratio on total energy expenditure. Design Randomized trial. Setting Multicenter collaboration at US two sites, August 2014 to May 2017.
C. Ebbeling, H. Feldman, Gloria L Klein, J. Wong, L. Bielak, Sarah K. Steltz, P. Luoto, R. Wolfe, W. Wong, D. Ludwig   +9 more
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source