Results 81 to 90 of about 853,705 (361)

Dehydroxylative radical N-glycosylation of heterocycles with 1-hydroxycarbohydrates enabled by copper metallaphotoredox catalysis

Nature Communications
N-Glycosylated heterocycles play important roles in biological systems and drug development. The synthesis of these compounds heavily relies on ionic N-glycosylation, which is usually constrained by factors such as labile glycosyl donors, precious metal ...
Da-Peng Liu, Xiao-Sen Zhang, Shuai Liu, Xiang-Guo Hu   +3 more
doaj   +1 more source

Ultrasound-assisted enzyme extraction and properties of Shatian pomelo peel polysaccharide

Ultrasonics Sonochemistry, 2023
In this study, Shatian pomelo peel was used as the raw material for extracting polysaccharides using hot water extraction (HW) and ultrasonic-assisted enzyme (UVE) methods, respectively.
Bobo Lin, Shasha Wang, Anqi Zhou, Qiurui Hu, Gangliang Huang   +4 more
doaj  

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

FEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski, Irene Cortijo, Shruti Bhargava, Bernard Jover, Fabrice Raynaud, Juliana H Boukhaled, Anne‐Dominique Lajoix, Vera Jankowski, Joachim Jankowski, Magali Cordaillat‐Simmons, Àngel Argilés, Nathalie Gayrard, Flore Duranton, Jonas Laget   +13 more
wiley   +1 more source

Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes.

Glycobiology, 2018
CAZypedia was initiated in 2007 to create a comprehensive, living encyclopedia of the carbohydrate-active enzymes (CAZymes) and associated carbohydrate-binding modules involved in the synthesis, modification and degradation of complex carbohydrates ...
W. Abbott, O. Alber, E. Bayer, J. Berrin, A. Boraston, H. Brumer, R. Brzezinski, A. Clarke, B. Cobucci-Ponzano, D. Cockburn, P. Coutinho, M. Czjzek, B. Dassa, G. Davies, V. Eijsink, Jens M. Eklöf, Alfons K G Felice, E. Ficko-Blean, Geoff Pincher, T. Fontaine, Z. Fujimoto, K. Fujita, S. Fushinobu, H. Gilbert, T. Gloster, E. Goddard-Borger, I. Greig, J. Hehemann, G. R. Hemsworth, B. Henrissat, Masafumi Hidaka, R. Hurtado‐Guerrero, K. Igarashi, T. Ishida, Š. Janeček, S. Jongkees, N. Juge, S. Kaneko, T. Katayama, M. Kitaoka, Naotake Konno, D. Kracher, A. Kulminskaya, A. L. V. Bueren, S. Larsen, Junho Lee, M. Linder, Leila LoLeggio, R. Ludwig, A. Luís, M. Maksimainen, B. Mark, Richard McLean, G. Michel, C. Montanier, M. Moracci, H. Mori, Hiroyuki Nakai, W. Nerinckx, T. Ohnuma, R. Pickersgill, K. Piens, T. Pons, E. Rebuffet, P. Reilly, M. Remaud-Siméon, B. Rempel, K. Robinson, D. Rose, J. Rouvinen, W. Saburi, Y. Sakamoto, M. Sandgren, F. A. Shaikh, Y. Shoham, F. S. John, J. Ståhlberg, M. Suits, G. Sulzenbacher, T. Sumida, R. Suzuki, B. Svensson, T. Taira, E. Taylor, T. Tonozuka, Breeanna R. Urbanowicz, G. Vaaje-Kolstad, W. Ende, A. Varrot, Maxime Versluys, F. Vincent, D. Vocadlo, W. Wakarchuk, T. Wennekes, Rohan J. Williams, Spencer J. Williams, D. Wilson, S. Withers, K. Yaoi, Vivian L. Y. Yip, Ran Zhang   +100 more
semanticscholar   +1 more source

GDP‐fucose transporter SLC35C1: a potential regulatory role in cytosolic GDP‐fucose and fucosylated glycan synthesis

FEBS Open Bio, EarlyView.
The inactivation of SLC35C1 (GDP‐fucose transporter) and enzymes involved in GDP‐fucose biosynthesis was studied. Fucose supplementation increases the level of GDP‐fucose to abnormal, millimolar values in the absence of the TSTA3 protein and SLC35C1 in contrast to the GMDS/SLC35C1 double mutant.
Edyta Skurska, Mariusz Olczak
wiley   +1 more source

Construction of hyperthermostable d‐allulose 3‐epimerase from Arthrobacter globiformis M30 using the sequence information from Arthrobacter psychrolactophilus

FEBS Open Bio, EarlyView.
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada, Kouhei Ohtani, Pushpa Kiran Gullapalli, Kazuhiko Ishikawa   +3 more
wiley   +1 more source

Lipid and Carbohydrate Metabolism in Caenorhabditis elegans

Genetics, 2017
Lipid and carbohydrate metabolism are highly conserved processes that affect nearly all aspects of organismal biology. Caenorhabditis elegans eat bacteria, which consist of lipids, carbohydrates, and proteins that are broken down during digestion into ...
J. Watts, M. Ristow
semanticscholar   +1 more source

Analysis of the regulation of undecaprenyl diphosphate dephosphorylation in Escherichia coli

FEBS Open Bio, EarlyView.
BacA, PgpB, and YbjG phosphatases are involved in undecaprenyl phosphate (C55P) synthesis in Escherichia coli. We analyzed the lipid contents and the gene expression in the gene‐disruption strains. Undecaprenyl diphosphate (C55PP) level increased in the bacA, ybjG double‐disruption strain, but C55P levels were similar in all strains.
Tomotaka Jitsukawa, Yasushi Shigeri, Shingo Fujisaki   +2 more
wiley   +1 more source

Interaction of class III cellobiose dehydrogenase with lytic polysaccharide monooxygenase

FEBS Open Bio, EarlyView.
The activity of lytic polysaccharide monooxygenase (LPMO) is supported by its auxiliary enzyme cellobiose dehydrogenase (CDH). The catalytic activity of both enzymes is coupled by electron transfer and a cyclic cascade generating substrates for both enzymes – hydrogen peroxide for LPMO and oxidized and non‐oxidized cellobiose and cello‐oligosaccharide ...
Angela Giorgianni, Florian Csarman, Peicheng Sun, Mirjam Kabel, Roland Ludwig   +4 more
wiley   +1 more source

Matrix: a complex amalgam of structures and functions in tumor microenvironment

FEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis, Evgenia Tsoukala, Theodora D. Sarantopoulou, Maria‐Elpida Christopoulou   +3 more
wiley   +1 more source