Results 141 to 150 of about 127,738 (290)

A Stable Isopterin Mimic of a Potent Bacterial Stimulant of T Cells

Chemistry – A European Journal, EarlyView.
A microbial metabolite covalently binds immunological protein MR1 to potently activate specific lymphocytes called MAIT cells, but it is too unstable for biological applications. Here, using synthesis, assays, protein crystallography, and computer modelling, we report a water‐stable analogue that activates reporter cells expressing the MAIT T cell ...
Jeffrey Y. W. Mak, Huy N. Hoang, Wael Awad, Xin Yi Lim, Damica D. Laurie, Ryan J. D. Rivero, James McCluskey, Alexandra J. Corbett, Jamie Rossjohn, David P. Fairlie   +9 more
wiley   +1 more source

Diagnostic Value of Serum Tumor Markers (Carcinoembryonic Antigen and Carbohydrate Antigen 19-9) in Gallbladder Cancer [PDF]

, 2019
Su young Hong, Hongbeom Kim, Youngmin Han, Yoonhyeong Byun, Eun Joo Kim, Jae Ri Kim, Wooil Kwon, Sun‐Whe Kim, Jin‐Young Jang   +8 more
openalex   +1 more source

Structure and Dynamics of Porin Loops in Asymmetric Outer Membranes of E. coli

Chemistry – A European Journal, EarlyView.
What are loops of membrane proteins doing within the oligosaccharide coat of cells? This structurally unexplored space is studied by solid‐state NMR, with the outer membrane protein G (OmpG) embedded in asymmetric E. coli outer membrane (OM) vesicles as a paradigmatic example.
Morgane Adélaïde, Jayasubba Reddy Yarava, Florian Lindemann, Massilia Abbas, Nils Cremer, Lisa Gerland, Matthias Hiller, Barth van Rossum, Dirk Linke, Alexander B. Barnes, Edward P. Saliba, Özkan Yildiz, Werner Kühlbrandt, Hartmut Oschkinat   +13 more
wiley   +1 more source

Detection of pancreatic cancer with normal carbohydrate antigen 19-9 using protein chip technology

, 2014
Xiaoli Jin
openalex   +1 more source

Fecal Microbiota Transplantation and Microbiota‐Based Therapeutics in Allogeneic Hematopoietic Stem Cell Transplantation: Current Evidence and Future Directions

Clinical Pharmacology &Therapeutics, EarlyView.
The intestinal microbiome is a key regulator of immune homeostasis, metabolism, and epithelial barrier integrity. In patients with malignant hematological diseases, particularly those undergoing hematopoietic stem cell transplantation, microbiome perturbations by reduced diversity, pathobiont expansion, and loss of beneficial metabolites are common as ...
Bálint Gergely Szabó, Dorina Korózs, Michal Bator, Krisztina Jeszenszky, Viktor Lakatos, László Gopcsa, Péter Reményi, János Sinkó   +7 more
wiley   +1 more source

Challenges and Pitfalls to Diagnosing NUTM1‐Rearranged Neoplasia of the Pancreas by Cytology and Ancillary Studies

Diagnostic Cytopathology, EarlyView.
ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
wiley   +1 more source

Biomarkers of lung congestion and injury in acute heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi, Gabriele Novello, Francesca Bursi, Anna Caretti, Noemi Furlotti, Ross Arena, Paola Argiento, Julio Núñez, Antoni Bayes‐Genis, Marco Metra   +9 more
wiley   +1 more source

Preoperative carbohydrate antigen 19-9 as a prognostic biomarker in colorectal cancer with synchronous peritoneal metastasis: multicentre cohort study. [PDF]

BJS Open
Tashiro K, Kajiwara Y, Ueno H, Kobayashi H, Kotake K, Sugihara K, Ajioka Y.   +6 more
europepmc   +1 more source

CardiLect: A combined cross‐species lectin histochemistry protocol for the automated analysis of cardiac remodelling

ESC Heart Failure, Volume 12, Issue 2, Page 1398-1415, April 2025.
Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely, Tamás Kovács, Andrea Kovács, Viktória E. Tóth, Nabil V. Sayour, Gábor M. Mórotz, Csenger Kovácsházi, Gábor B. Brenner, Zsófia Onódi, Balázs Enyedi, Domokos Máthé, Przemyslaw Leszek, Zoltán Giricz, Péter Ferdinandy, Zoltán V. Varga   +14 more
wiley   +1 more source

Prostate cancer presenting as brain metastasis with concurrent elevation of carcinoembryonic antigen and carbohydrate antigen 19-9 levels: illustrative case. [PDF]

J Neurosurg Case Lessons
Sumiyoshi S, Fujii K, Kasashima K, Oda M, Saiki M.   +4 more
europepmc   +1 more source