Results 111 to 120 of about 85,340 (302)

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

SINTESI E PROPRIETA’ BIOLOGICHE DI LIGANDI GLICOSIDICI MULTIVALENTI [PDF]

, 2009
Protein-carbohydrate interactions are at the heart of many important biological processes as the adesion of bacteria and viruses to the cell surfaces.
Moni, Lisa
core  

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

Structures of parasite calreticulins provide insights into their flexibility and dual carbohydrate/peptide-binding properties

IUCrJ, 2016
Calreticulin (CRT) is a multifaceted protein, initially discovered as an endoplasmic reticulum (ER) chaperone protein, that is essential in calcium metabolism.
Christophe Moreau, Gianluca Cioci, Marina Iannello, Emmanuelle Laffly, Anne Chouquet, Arturo Ferreira, Nicole M. Thielens, Christine Gaboriaud   +7 more
doaj   +1 more source

Water Permeates and Plasticizes Amorphous Carbon Dots: Unraveling the Inner Accessibility of the Nanoparticles by Glass Transition Studies

Advanced Materials, EarlyView.
The water permeability of amorphous carbon dots (CDs) is demonstrated by investigating their plasticization. Novel polyamide‐based and amorphous nanoparticles are synthesized by controlling their inner packing density. Water plasticization is evidenced by the decrease of the CDs glass transition temperature with increasing the hydration degree.
Elisa Sturabotti, Valerio Di Lisio, Lucia Cardo, Alessandro Camilli, Estela Moretón Alfonsín, Daniele Cangialosi, Amaia Iturrospe Ibarra, Arantxa Arbe, Maurizio Prato   +8 more
wiley   +1 more source

Crystal structure and hydrogen bonding in N-(1-deoxy-β-d-fructopyranos-1-yl)-2-aminoisobutyric acid

Acta Crystallographica Section E: Crystallographic Communications, 2018
The title compound, alternatively called d-fructose-2-aminoisobutyric acid (FruAib), C10H19NO7, (I), crystallizes exclusively in the β-pyranose form, with two conformationally non-equivalent molecules [(IA) and (IB)] in the asymmetric unit.
Valeri V. Mossine, Charles L. Barnes, Thomas P. Mawhinney   +2 more
doaj   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Electrically Readable Lateral Flow Assay Using Organic Transistors for Diagnostic Applications

Advanced Materials, EarlyView.
Electrolyte‐gated organic field‐effect transistors (EGOFETs) are integrated with lateral flow (LF) paper fluidics to create a reusable, portable, and low‐cost point‐of‐care (PoC) diagnostic test. The devices are validated for Human Immunoglobulin G detection, achieving high sensitivity (0.1 fm), selectivity, and reproducibility with rapid results in 20–
María Jesús Ortiz‐Aguayo, Carme Martínez‐Domingo, Diego Gutiérrez, Dean Kos, Marta Mas‐Torrent   +4 more
wiley   +1 more source

Production of functional human galectin-1 in transplastomic tobacco and simplified recovery via batch-mode purification

Frontiers in Plant Science
Plant molecular farming has established itself as a transformative technology for the cost-effective and sustainable production of biopharmaceuticals, offering scalable solutions to meet growing global demand.
Catalina Francisca Vater, Catalina Francisca Vater, Juan Manuel Pérez Sáez, Juan Carlos Stupirski, Mora Massaro, Federico Gabriel Mirkin, Fernando Félix Bravo-Almonacid, Fernando Félix Bravo-Almonacid, Gabriel Adrián Rabinovich, Gabriel Adrián Rabinovich, Gabriel Adrián Rabinovich, Mauro Miguel Morgenfeld, Mauro Miguel Morgenfeld   +12 more
doaj   +1 more source