Investigation of Carbohydrate Recognition via Computer Simulation [PDF]
Molecules, 2015 Carbohydrate recognition by proteins, such as lectins and other (bio)molecules, can be essential for many biological functions. Recently, interest has arisen due to potential protein and drug design and future bioengineering applications.
Quentin R. Johnson +3 more
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Identification of a carbohydrate recognition motif of purinergic receptors [PDF]
eLife, 2023 As a major class of biomolecules, carbohydrates play indispensable roles in various biological processes. However, it remains largely unknown how carbohydrates directly modulate important drug targets, such as G-protein coupled receptors (GPCRs).
Lifen Zhao +7 more
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Targeting undruggable carbohydrate recognition sites through focused fragment library design [PDF]
Communications Chemistry, 2022 Carbohydrate–protein interactions are key for cell–cell and host–pathogen recognition, but their hydrophilic nature makes the development of drug-like inhibitors a challenge.
Elena Shanina +11 more
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Glycan microarray analysis of the carbohydrate-recognition specificity of native and recombinant forms of the lectin ArtinM [PDF]
Data in Brief, 2015 This article contains data related to the researc.h article entitled “Yeast-derived ArtinM shares structure, carbohydrate recognition, and biological effects with native ArtinM” by Cecílio et al. (2015) [1].
Y. Liu +4 more
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An Orthogonal ‘Clickable’ Xyloside Scaffold in 4C1 and 1C4 Conformation [PDF]
MoleculesGlycoclusters are important molecular tools for studying carbohydrate–protein interactions. It is advantageous to derive glycoclusters from carbohydrate-based scaffolds.
Lorenz Pietsch +2 more
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Carbohydrate Recognition Specificity of Trans-sialidase Lectin Domain from Trypanosoma congolense. [PDF]
PLoS Neglected Tropical Diseases, 2015 Fourteen different active Trypanosoma congolense trans-sialidases (TconTS), 11 variants of TconTS1 besides TconTS2, TconTS3 and TconTS4, have been described.
Mario Waespy +9 more
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Structural Characterization of a Proto-Type Galectin from Cinachyrella sp. and Evaluation of Its Selective Bacterial Glycan Recognition and Antibiofilm Activity [PDF]
MicroorganismsMarine sponges represent a rich source of lectins with diverse biological activities and biotechnological potential. In this study, we report the purification and comprehensive biochemical and structural characterization of a lectin (CspL) from the ...
Juliana Sampaio Nogueira Marques +13 more
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Platform Synthetic Lectins for Divalent Carbohydrate Recognition in Water [PDF]
Angewandte Chemie - International Edition, 2016 Anthony P. Davis +2 more
exaly +2 more sources
A Comprehensive Phylogenetic and Bioinformatics Survey of Lectins in the Fungal Kingdom
Journal of Fungi, 2021 Fungal lectins are a large family of carbohydrate-binding proteins with no enzymatic activity. They play fundamental biological roles in the interactions of fungi with their environment and are found in many different species across the fungal kingdom ...
Annie Lebreton +5 more
doaj +1 more source
Assessment of Carbohydrate Content Estimation among Adolescents with Type 1 Diabetes and their Glycemic Control [PDF]
Egyptian Journal of Health Care, 2023 Background: Carbohydrate content estimation is one of the techniques in diet management that can provide flexibility in choosing food and can help adolescents with type 1 diabetes mellitus (T1DM) to identify blood glucose patterns.
Dalia Abdel Mordy Baiomy +3 more
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