Results 31 to 40 of about 2,048 (147)

First genome sequence of a European Alternaria brassicae isolate and genes involved in early development of alternaria leaf spot on Brassica juncea

Pest Management Science, EarlyView.
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King, Graham McLaughlin, Chinthani S. Karandeni Dewage, Zedi Gao, David J. Hughes, Jonathan S. West, Henrik U. Stotz   +6 more
wiley   +1 more source

Revisiting the Molecular Roadmap for Sugar Crops: Genome Reading, Trait Writing and Variety Redesigning

Plant Biotechnology Journal, EarlyView.
ABSTRACT Sugar crops, including but not limited to sugarcane, sugar beet, sweet sorghum and stevia, are major sources of sugar production in the world. However, conventional breeding approaches, limited by long breeding cycles, low efficiency and restricted capacity to improve complex traits in sugar crops, are increasingly insufficient to address the ...
Peilin Wang, Qibin Wu, Wenzhi Wang, Prakash Lakshmanan, Yangrui Li, Khushi Muhammad, Yuguang Wang, Youxiong Que   +7 more
wiley   +1 more source

Impact of 14 days of head‐down bed rest and an exercise countermeasure on skeletal muscle atrophy, proteome and circulatory cytokines in older adults

Experimental Physiology, EarlyView.
Abstract Prolonged bed rest and immobilization have deleterious effects on skeletal muscle mass and function, especially in older adults. These can lead to reduced physical capacity and quality of life. Previous experiments in younger individuals show that exercise can mitigate these effects, but evidence remains scarce and inconclusive in older adults.
Jean‐Christophe Lagacé, Philippe St‐Martin, Mariano Avino, Ahmed Ghachem, Guy Hajj‐Boutros, Jose A. Morais, Jamie S. McPhee, Karen Lambert, Eléonor Riesco, Isabelle J. Dionne   +9 more
wiley   +1 more source

Gut Microbiota Alterations in Myelodysplastic Neoplasms Are Associated With Immune Dysfunction and the Therapeutic Mechanism of Hypomethylating Agents

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background Myelodysplastic neoplasms (MDS) represent a group of heterogeneous clonal disorders characterized by immune dysregulation in their pathogenesis. Gut microbiota dysbiosis plays a critical role in immune modulation. Methods We collected the fecal samples of 23 newly diagnosed MDS, 10 hypomethylating agents (HMA) treated MDS and 13 age
Zhongxun Shi, Fei Huang, Chengrong Luo, Lu Yang, Yu Chen, Chun Qiao, Rong Wang, Yan Wang, Yining Yan, Linlin Wang, Lei Fan, Wenyi Shen   +11 more
wiley   +1 more source

Decoding the Hexosamine Biosynthesis Pathway: Implications for Novel Therapeutic Strategies in Sarcoma

Journal of Cellular Physiology, Volume 241, Issue 5, May 2026.
ABSTRACT Cancer cells rewire their metabolism to sustain a high proliferation rate. Sensing external cues is essential to match the metabolic fluxes of the cells to the external stimuli. As part of the glucose metabolism, the hexosamine biosynthesis pathway (HBP) is considered a nutrient‐sensing pathway. The HBP produces UDP‐GlcNAc, a key precursor for
Pegah Rahimizadeh, Richard Miallot, Chelsea De Bellis, Philippe Jolivet, Joanna Przybyl   +4 more
wiley   +1 more source

Germin and germin-like proteins: evolution, structure, and function [PDF]

, 2008
Germin and germin-like proteins (GLPs) are encoded by a family of genes found in all plants. They are part of the cupin superfamily of biochemically diverse proteins, a superfamily that has a conserved tertiary structure, though with limited similarity ...
Dunwell, Jim, Gibbings, J. George, Mahmood, Tariq, Saqlan Naqvi, S.M.   +3 more
core   +1 more source

Engineering Chondroitinase‐Free Baculovirus‐Insect Cell Expression System for Efficient Synthesis of Chondroitin Sulphates

Microbial Biotechnology, Volume 19, Issue 5, May 2026.
An engineered baculovirus‐insect cell platform produces chondroitinase‐free sulfotransferases, enabling efficient synthesis of chondroitin sulphates. ABSTRACT Owing to the high expression levels, proper protein folding and post‐translational modifications, baculovirus‐insect cell expression system is an ideal platform for producing active chondroitin ...
Junyue Li, Yuqing Tian, Lihe She, Zhangliang Liu, Yingying Zhou, Yanyan Wang, Jihui Zhang, Leilei Zhu, Huarong Tan, Jine Li   +9 more
wiley   +1 more source

Several Hfq-dependent alterations in physiology of Yersinia enterocolitica O:3 are mediated by derepression of the transcriptional regulator RovM [PDF]

, 2017
In bacteria, the RNA chaperone Hfq enables pairing of small regulatory RNAs with their target mRNAs and therefore is a key player of post-transcriptional regulation network. As a global regulator, Hfq is engaged in the adaptation to external environment,
Bengoechea, José A, Fernández-Carrasco, Helena, Leskinen, Katarzyna, Pajunen, Maria I, Skurnik, Mikael, Varjosalo, Markku   +5 more
core   +1 more source

The Basic Helix–Loop–Helix Transcription Factors UvBhlh1 and UvBhlh6 Coordinate Virulence in the Rice False Smut Fungus Ustilaginoidea virens

Molecular Plant Pathology, Volume 27, Issue 5, May 2026.
Transcription factors UvBhlh1 and UvBhlh6 are essential for early infection and virulence in Ustilaginoidea virens. These two proteins form a heterodimer that cooperatively regulates downstream target genes during pathogenesis. ABSTRACT Ustilaginoidea virens is the causal agent of rice false smut, a devastating and globally widespread fungal disease ...
Huijuan Cao, Hao Gong, Xiaohong Huang, Jialin Lei, Mina Yu, Xiayan Pan, Tianqiao Song, Junjie Yu, Zhongqiang Qi, Yan Du, Rongsheng Zhang, Yongfeng Liu   +11 more
wiley   +1 more source

Computational insights into carbohydrate epimerase mechanisms

, 2023
[eng] Carbohydrates, as the most abundant biomolecules, play a myriad of roles and functions in biological systems. Unlike the building blocks of proteins, amino acids, whose chemical structure can vary significantly, monosaccharides, the building blocks of carbohydrates, can exhibit small differences in their chemical structure that lead to a very ...
openaire   +2 more sources