Results 21 to 30 of about 24,522 (155)

Peroxisome proliferator‐activated receptor gamma (PPARγ) regulates lactase expression and activity in the gut

EMBO Molecular Medicine, 2017
Lactase (LCT) deficiency affects approximately 75% of the world's adult population and may lead to lactose malabsorption and intolerance. Currently, the regulation of LCT gene expression remains poorly known.
Mathurin Fumery, Silvia Speca, Audrey Langlois, Anne‐Marie Davila, Caroline Dubuquoy, Marta Grauso, Anthony Martin Mena, Martin Figeac, Daniel Metzger, Christel Rousseaux, Jean‐Frederic Colombel, Laurent Dubuquoy, Pierre Desreumaux, Benjamin Bertin   +13 more
doaj   +1 more source

Lactose intolerance and gastrointestinal cow’s milk allergy in infants and children – common misconceptions revisited

World Allergy Organization Journal, 2017
Lactose is the main carbohydrate in human and mammalian milk. Lactose requires enzymatic hydrolysis by lactase into D-glucose and D-galactose before it can be absorbed.
Ralf G. Heine, Fawaz AlRefaee, Prashant Bachina, Julie C. De Leon, Lanlan Geng, Sitang Gong, José Armando Madrazo, Jarungchit Ngamphaiboon, Christina Ong, Jossie M. Rogacion   +9 more
doaj   +3 more sources

The role of carbohydrate malabsorption syndrome in the pathogenesis of rotavirus diarrhea (a literature review)

Zaporožskij Medicinskij Žurnal
The aim – to summarize literature data on the pathogenetic mechanisms of the diarrheal syndrome development in children with rotavirus infection and to determine the role of carbohydrate malabsorption syndrome in it through a complex analysis of ...
O. V. Usachova, N. V. Vorobiova, E. A. Silina, T. B. Matvieieva   +3 more
doaj   +1 more source

A systematic review and meta-analysis on the prevalence of non-malignant, organic gastrointestinal disorders misdiagnosed as irritable bowel syndrome

Scientific Reports, 2022
Treatable gastrointestinal disorders in patients with symptoms typical for irritable bowel syndrome (IBS) may be overlooked. The prevalence of five gastrointestinal conditions—bile acid diarrhoea (BAD), carbohydrate malabsorption (CM), microscopic ...
Dennis Poon, Graham R. Law, Giles Major, H. Jervoise N. Andreyev   +3 more
doaj   +1 more source

Biomolecular Fingerprint of Crohn's Disease: A Comparative Raman Spectroscopic Study of Blood and Tissue Samples. [PDF]

J Biophotonics
Raman spectroscopy is evaluated as a minimally invasive tool for diagnosing and monitoring Crohn's disease. Correlation between plasma and tissue spectra indicates that plasma measurements reflect local intestinal inflammation, while therapy‐associated biochemical shifts toward healthy profiles highlight its potential for disease monitoring and ...
Ghauri MD, Fernandez MV, Santacroce G, Chanda S, Zammarchi I, Capobianco I, Sekar SKV, Ghosh S, Komolibus K, Andersson-Engels S, Iacucci M, Gautam R.   +11 more
europepmc   +2 more sources

Complex carbohydrate malabsorption in exocrine pancreatic insufficiency. [PDF]

Gut, 1993
The magnitude of complex carbohydrate malabsorption in exocrine pancreatic insufficiency has not been well quantified in the past. The quantity of carbohydrate malabsorbed after a rice starch (100 g) meal in 20 patients with chronic pancreatitis (n = 10) or pancreatic cancer (n = 10) was therefore estimated.
LADAS, SD, GIORGIOTIS, K, RAPTIS, SA
openaire   +3 more sources

Hydrogen breath test as a diagnostic tool

Quality in Sport
Introduction and Purpose: Hydrogen breath tests serve the crucial purpose of evaluating the absorption of nutrients in the small intestine, particularly when carbohydrates are not properly absorbed, leading to bacterial overgrowth.
Natalia Zozula, Zuzanna Tomczewska, Aleksandra Rykucka, Marcin Wąs, Aleksandra Latała, Justyna Kiełbasa, Agata Kowalczyk, Katarzyna Bil, Iga Ślesicka, Magda Przestrzelska   +9 more
doaj   +1 more source

Expanding the genotypic spectrum of PCSK1 deficiency: A novel mutation in severe neonatal diarrhea

JPGN Reports, EarlyView.
Abstract Among congenital diarrhea and enteropathies (CODEs), proprotein convertase subtilisin/kexin type 1 (PCSK1) deficiency is a rare monogenic disorder, associated with severe neonatal diarrhea and polyendocrinopathies. We report an 18‐day‐old male neonate, born to consanguineous parents, presenting with persistent watery diarrhea, metabolic ...
Eleonora Saraceno, Angelo Corso Faini, Silvia Deaglio, Marianna Pellegrini, Raffaele Buganza, Francesca Giuliani, Pier Luigi Calvo, Michele Pinon   +7 more
wiley   +1 more source

A pilot intervention study to evaluate compliance to a peptide-based oral nutritional supplement in an adult population with impaired gastrointestinal function

Clinical Nutrition Experimental, 2019
Summary: Background: Patients with gastrointestinal dysfunction have a reduced ability to digest and absorb nutrients and are often unable to tolerate oral nutritional supplements (ONS) containing whole protein. Peptide-based formulas have been shown to
Jeffrey L. Nelson
doaj   +1 more source

PERCC1‐associated enteropathy: Diagnostic challenges and enteral autonomy achieved with teduglutide

JPGN Reports, EarlyView.
Abstract Congenital diarrheas and enteropathies (CODE) are rare inherited disorders characterized by early‐onset intractable diarrhea. Though progress has been made in elucidating the genetic basis of CODE, much remains to be discovered. Another challenge is the lack of curative therapies—treatment is primarily supportive including enteral and ...
Angela Tran, Vivien Nguyen, Phuong Huynh
wiley   +1 more source