Results 31 to 40 of about 148,113 (146)

The risk of epilepsy after neonatal seizures

Developmental Medicine &Child Neurology, EarlyView.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16288 Abstract Aim To estimate the cumulative risk of epilepsy after neonatal seizures and identify subpopulations at increased risk. Method This was a nationwide register‐based cohort study including all children born in Denmark between 1997 and 2018.
Jeanette Tinggaard, Signe V. Pedersen, Mads L. Larsen, Andreas K. Jensen, Gorm Greisen, Bo M. Hansen, Christina E. Hoei‐Hansen   +6 more
wiley   +1 more source

Incidence and patterns of inborn errors of metabolism in the Eastern Province of Saudi Arabia, 1983-2008

Annals of Saudi Medicine, 2010
Background and Objectives :Individual inborn errors of metabolism (IEM) are rare disorders, but may not be that uncommon in our patient population. We report the incidence of IEM in a defined cohort of births at the Saudi Aramco medical facilities in the
Moammar Hissa, Cheriyan George, Mathew Revi, Al-Sannaa Nouriya   +3 more
doaj  

Highly sensitive and selective sugar detection by terahertz nano-antennas [PDF]

arXiv, 2015
Molecular recognition and discrimination of carbohydrates are important because carbohydrates perform essential roles in most living organisms for energy metabolism and cell-to-cell communication. Nevertheless, it is difficult to identify or distinguish various carbohydrate molecules owing to the lack of a significant distinction in the physical or ...
arxiv  

An overview of insulin therapy for the non‐specialist

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Nearly all health professionals, whatever their practice or speciality, now have contact with a significant number of insulin‐using people with diabetes. People with type 1 diabetes are nearly universally managed on more complex insulin regimens, increasingly with complex support technology, and with some understanding of the concepts ...
Philip D. Home
wiley   +1 more source

Hierarchical modularity of nested bow-ties in metabolic networks [PDF]

BMC Bioinformatics 2006, 7:386, 2006
The exploration of the structural topology and the organizing principles of genome-based large-scale metabolic networks is essential for studying possible relations between structure and functionality of metabolic networks. Topological analysis of graph models has often been applied to study the structural characteristics of complex metabolic networks ...
arxiv  

Effect of a Behavioral Change Communication Strategy Coupled With Small‐Quantity Lipid‐Based or Micro‐Nutrient Supplements on Stunting and Obesity in Children in Baja Verapaz, Guatemala: Results From a Cluster Randomized Controlled Trial

Maternal &Child Nutrition, EarlyView.
Coupling a multilevel participatory‐ludic BCC strategy with the use of unsweetened SQ‐LNS reduces the risk of being overweight or obese in infants and young children from Guatemala. Yet, complementary interventions to address non‐nutritional factors related to stunting in Guatemala are needed. ABSTRACT The co‐existence of childhood stunting and obesity
Carolina Gonzalez Acero, Sebastian Martinez, Ana Perez‐Exposito, Solis Winters   +3 more
wiley   +1 more source

The start of the Abiogenesis: Preservation of homochirality in proteins as a necessary and sufficient condition for the establishment of the metabolism [PDF]

arXiv, 2018
Biosystems contain an almost infinite amount of vital important details, which together ensure their life. There are, however, some common structures and reactions in the systems: the homochirality of carbohydrates and proteins, the metabolism and the genetics.
arxiv  

Modulation of lignin and anthocyanin homeostasis by GTP cyclohydrolase1 in maize

Plant Biotechnology Journal, EarlyView.
Summary Maize is a key biomass resource with wide agricultural applications. Anthocyanins, potent antioxidants, offer health benefits like reducing oxidative stress. The biosynthesis of anthocyanins competes with that of lignin for shared metabolic precursors, which can lead to trade‐offs in plant growth and feed quality.
Mingyue Zhang, Xiaohan Li, Xiao Wang, Shuzhen Jiang, Junli Zhang, Mingfei Sun, Zixian Zhou, Jinxiao Zhang, Mengyao Li, Yanxiao Lv, Enlong Qi, Ziang Tian, Hongjie Zhu, Xuebin Zhang, Xiangyu Zhao, Changcheng Xu, Thomas Lübberstedt, Xiansheng Zhang, Xuerong Yang, Chao Zhou, Hongjun Liu   +20 more
wiley   +1 more source

Aging as a mechanism for type 2 diabetes mellitus [PDF]

Journal of Diabetes & Metabolism, 2018
Background: The human intestines are colonized by a variety of bacterial phyla that with the host co-ordinate numerous metabolic processes in health and disease. As such the intestinal microbiome can positively and adversely affect end organ physiological functions (e.g., liver, skeletal muscle, adipose tissue). Several studies have shown that the gut
openaire   +7 more sources

Elucidation of Mechanism of Action in Drug Invention: Using Stable Isotope Tracers to Unravel Biochemical Kinetics

Pharmacology Research &Perspectives, Volume 13, Issue 3, June 2025.
ABSTRACT The invention of a therapeutic begins by characterizing features that differentiate healthy versus diseased states; this often presents as changes in the concentration of an analyte. Examples include elevated blood glucose in diabetes, high cholesterol in heart disease, and protein aggregation in neurodegeneration.
Rebecca A. Kohnz, Dan Zhou, Bin Lou, Huifang Yao, David McKenney, Dhiraj Dokwal, Ruth Villanueva, Heidi Kocalis, Jeanine E. Ballard, Jennifer Piesvaux, Stephen F. Previs   +10 more
wiley   +1 more source