Results 101 to 110 of about 21,815 (192)

Advances in Electrical Materials for Bone and Cartilage Regeneration: Developments, Challenges, and Perspectives

open access: yesAdvanced Science, EarlyView.
This review explores the challenges of treating bone and cartilage defects, emphasizing the role of endogenous electric fields in bone and cartilage regeneration. It highlights recent advancements in electroactive biomaterials, including nanogenerators, piezoelectric materials, triboelectric scaffold, and zwitterionic hydrogels.
Yubin Yao   +4 more
wiley   +1 more source

Body weight dynamics and cardiovascular risk factors in climacteric women

open access: yesКардиоваскулярная терапия и профилактика, 1970
Aim. To compare body weight (BW), lipid and carbohydrate metabolism dynamics in premenopausal, menopausal, and postmenopausal women. Material and methods. This cohort study included 573 volunteers aged 36-55 years.
A. A. Popov   +5 more
doaj  

Pepticombisomes: Biomimetic Vesicles Crafted From Recombinant Supercharged Polypeptides with Uniformly Distributed Side‐Chains

open access: yesAdvanced Science, EarlyView.
Pepticombisomes are biomimetic vesicles formed by elastin‐like supercharged unfolded polypeptides (SUPs) uniformly functionalized with anionic surfactants with lipid‐like hydrophobic tails. The molecular design of these supramolecular combs enables precise assembly into membranes with controlled thickness and flexibility.
Dominik Söder   +8 more
wiley   +1 more source

The relationship between chlorophyllous spores and mycorrhizal associations in ferns: evidence from an evolutionary approach

open access: yesAmerican Journal of Botany, Volume 109, Issue 12, Page 2068-2081, December 2022., 2022
Abstract Premise Approximately 14% of all fern species have physiologically active chlorophyllous spores that are much more short‐lived than the more common and dormant achlorophyllous spores. Most chlorophyllous‐spored species (70%) are epiphytes and account for almost 37% of all epiphytic ferns.
Daniela Mellado‐Mansilla   +6 more
wiley   +1 more source

Synthetic Lethality of SHP2 and XIAP Suppresses Proliferation and Metastasis in KRAS‐mutant Nonsmall Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
Embelin cotargets SHP2 to disrupt the SHP2/GRB2/SOS complex, inhibiting cancer‐related signaling pathways such as MAPK, (PI3K)/AKT pathway, and XIAP to induce apoptosis signaling pathway, respectively, leading to synthetic lethality in KRAS‐mutant NSCLC cells both in vivo and in vitro.
Nai‐jie Fu   +8 more
wiley   +1 more source

The Novel Dual GIP and GLP‐1 Receptor Agonist Tirzepatide Attenuates Colon Cancer Development by Regulating Glucose Metabolism

open access: yesAdvanced Science, EarlyView.
Tirzepatide, a dual GIP/GLP‐1 receptor agonist for diabetes, suppresses colorectal cancer growth by targeting glucose metabolism. It inhibits cancer cell proliferation, promotes apoptosis, and induces tumor regression. It reduces glucose uptake and destabilizes HIF‐1α for degradation to downregulate PFKFB3/PFK‐1 enzymes, thus contributing to the ...
Yikai Zhang   +11 more
wiley   +1 more source

Microneedles at the Forefront of Next Generation Theranostics

open access: yesAdvanced Science, EarlyView.
The TOC figure illustrates the revolutionary role of microneedles in modern medicine, showcasing their dual diagnostic and therapeutic functions. On the left, microneedles access interstitial fluid for real‐time monitoring of biomarkers like glucose and hormones.
Chan Wang   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy