Results 51 to 60 of about 21,815 (192)

METABOLIC STATE OF BLOOD LYMPHOCYTES IN CHRONIC MYELOID LEUKEMIA AND CHRONIC LYMPHOID LEUKEMIA

Медицинская иммунология, 2014
. We examined metabolic status of blood lymphocytes in forty-four patients with chronic myeloid leukemia (CML), and in fifty-seven patients with chronic lymphoid leukemia (CLL).
O. V. Smirnova, V. T. Manchuk, A. A. Savchenko   +2 more
doaj   +1 more source

FXa‐Responsive Hydrogels to Craft Corneal Endothelial Lamellae

Advanced Healthcare Materials, EarlyView.
This study introduces a sacrificial, multicomponent biohybrid hydrogel system enabling stable scaffold‐free tissue engineering. Its efficacy is demonstrated through the ex vivo development, detachment, and transplantation of human corneal endothelial lamellae, achieving clinically relevant sizes for Descemet Membrane Endothelial Keratoplasty.
Mikhail V. Tsurkan, Juliane Bessert, Rabea Selzer, Sarah D. Tsurkan, Dagmar Pette, Manfred F. Maitz, Petra B. Welzel, Carsten Werner   +7 more
wiley   +1 more source

Leveraging Organ‐on‐Chip Models to Investigate Host–Microbiota Dynamics and Targeted Therapies for Inflammatory Bowel Disease

Advanced Healthcare Materials, EarlyView.
The challenges of studying inflammatory bowel disease (IBD), highlighting limitations of traditional 2D cell cultures and animal models are discussed here. It introduces human intestine organ‐on‐chip (OoC) models as a promising alternative, capable of more accurately mimicking the intestinal microenvironment.
Tim Kaden, Raquel Alonso‐Román, Johannes Stallhofer, Mark S. Gresnigt, Bernhard Hube, Alexander S. Mosig   +5 more
wiley   +1 more source

Self‐Doped and Biodegradable Glycosaminoglycan‐PEDOT Conductive Hydrogels Facilitate Electrical Pacing of iPSC‐Derived Cardiomyocytes

Advanced Healthcare Materials, EarlyView.
The electrical properties and performance of conductive hydrogels based on sulfated‐glycosaminoglycan‐PEDOT (poly 3,4‐ethylenedioxythiophene) brush copolymers is studied, showing that the higher sulfation degree of heparin confers hydrogels with the highest conductivity.
Daniel Hachim, Olivia Hernández‐Cruz, James E. J. Foote, Richard Wang, Matthew W. Delahaye, Daniel J. Stuckey, Zhiping Feng, Jonathan P. Wojciechowski, Luke C. B. Salter, Junliang Lin, Sian E. Harding, Molly M. Stevens   +11 more
wiley   +1 more source

3D Microtumors Representing Ovarian Cancer Minimal Residual Disease Respond to the Fatty Acid Oxidation Inhibitor Perhexiline

Advanced Healthcare Materials, EarlyView.
Minimal residual disease (MRD) leads to cancer relapse and poor survival in ovarian cancer. The lack of representative 3D models limits therapy development. The microfluidics‐based high throughput 3D microtumor platform described here generates clinically‐relevant MRD models. The 3D microtumors recapitulate the molecular signatures of MRD from patients.
Xingyun Yang, Mara Artibani, Yongcheng Jin, Aneesh Aggarwal, Yujia Zhang, Sandra Muñoz‐Galvan, Ellina Mikhailova, Lena Rai, Nobina Mukherjee, Ravinash Krishna Kumar, Ashwag Albukhari, Shaohua Ma, Linna Zhou, Ahmed Ashour Ahmed, Hagan Bayley   +14 more
wiley   +1 more source

The Role of Glycated Hemoglobin in the Diagnosis and Monitoring of Diabetes Mellitus

Mìžnarodnij Endokrinologìčnij Žurnal, 2014
Considering the prevalence of diabetes mellitus, the possibility of early and rapid progress of complications, a large number of undiagnosed cases and disappointing forecasts of the WHO on the prospects of diabetes mellitus spreading in the world, timely
L.А. Lutsenko
doaj   +1 more source

Novel Protein‐Rich Bioactive Bioink Stimulates Cellular Proliferation and Response in 3D Bioprinted Volumetric Constructs

Advanced Healthcare Materials, EarlyView.
This work describes a protein‐rich, low‐cost, bioactive bioink, prepared by adding eggwhite powder to functionalize an established alginate‐methylcellulose hydrogel blend and enhance its cellular response. The bioink not only maintains favorable printability and high shape fidelity but also exhibits remarkable bioactivity, thereby improving the ...
Suihong Liu, David Kilian, Anne Bernhardt, Katharina Wirsig, Max von Witzleben, Sarah Duin, Anja Lode, Qingxi Hu, Michael Gelinsky   +8 more
wiley   +1 more source

VITAMIN D IN POSTMENOPAUSAL WOMEN IN NOVOSIBIRSK WITH A DIFFERENT STATE OF CARBOHYDRATE METABOLISM

Бюллетень сибирской медицины, 2014
The aim of the study was to evaluate the association of vitamin D status with carbohydrate metabolism and anthropometric status in postmenopausal Novosibirsk women.We analyzed correlations of carbohydrate metabolism parameters and body weight with ...
L. A. Ruyatkina, D. S. Ruyatkin, I. S. Iskhakova, V. V. Romanov   +3 more
doaj   +1 more source

Lycium‐Barbarum Polysaccharide‐Loaded Dual‐Crosslinked Rigid Hydrogel Enhances Bone Healing in Diabetic Bone Defects by Scavenging Reactive Oxygen Species

Advanced Healthcare Materials, EarlyView.
A novel hydrogel (HLBP) incorporating natural polysaccharides from goji berries is developed to enhance diabetic bone defect healing. The hydrogel efficiently scavenges ROS, improves osteogenic differentiation, and promotes in vivo bone regeneration. This strategy offers a biocompatible and localized approach, overcoming the challenges of traditional ...
Wenjie Zhong, Wenao Liao, Lingcong Xu, Niezhenghao He, Ke Xu, Caiyuan Liu, Fei Wang, Wei Zhang, Jiang Hu, Haowen Cui   +9 more
wiley   +1 more source

The protein interactome of Escherichia coli carbohydrate metabolism.

PLoS ONE
We investigate how protein-protein interactions (PPIs) can regulate carbohydrate metabolism in Escherichia coli. We specifically investigated the stoichiometry of 378 PPIs involving carbohydrate metabolic enzymes. In 48 interactions, the interactors were
Shomeek Chowdhury, Stephen S Fong, Peter Uetz   +2 more
doaj   +1 more source