Results 51 to 60 of about 286,788 (315)

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source

Response to allopurinol and febuxostat according to the fractional excretion of urate in men with gout

Arthritis Care &Research, Accepted Article.
Background Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of urate (FEUA) also modulates this response and relates to oxypurinol concentrations. We further evaluated its potential influence
Pascal Richette, Anouk Walter‐Petrich, Quang Dinh Nguyen, Matthieu Resche‐Rigon, Quang Huy Dinh Nguyen, Minh Duc Do, Thao Phuong Mai, Tuan Duc Nguyen, Fernando Perez‐Ruiz, Emmanuel Letavernier, Tristan Pascart, Augustin Latourte, Hang Korng Ea, Thomas Bardin   +13 more
wiley   +1 more source

INFLUENCE OF COVERT CARBOHYDRATE METABOLISM DISORDERS ON THE RISK OF KIDNEY FUNCTION DECLINE

Российский кардиологический журнал, 2016
Aim. To assess the relation of covert carbohydrate metabolism disorders in patients with acute coronary syndrome (ACS) and declined kidney filtration after percutaneous coronary intervention (PCI).Material and methods.
N. T. Vatutin, M. I. Zinkovych, E. D. Yakubenko   +2 more
doaj   +1 more source

Imaging of Lipid Droplets in Living Cells and Mice with Metabolic Dysfunction‐Associated Steatotic Liver Disease via a Galactose‐Modified Supramolecular Near‐Infrared Fluorescent Glycoprobe

Advanced Functional Materials, EarlyView.
A galactose‐modified supramolecular near‐infrared (NIR) glycoprobe, TCF‐FBN@Gal‐BSA, enables targeted delivery to the liver through the asialoglycoprotein receptor (ASGPR) and facilitates liver‐targeting fluorescence visualization of lipid droplets (LDs) in metabolic dysfunction‐associated steatotic liver disease (MASLD) mice.
Han‐Min Wang, Lei Dong, Qiu‐Lian Hao, Lu‐Lu Sun, Xin‐Rong Li, Yu‐Wei Yuan, Ming‐Ye Tang, Jin Gong, Yi Zang, Jia Li, Tony D. James, Xiao‐Peng He, Hai‐Hao Han   +12 more
wiley   +1 more source

Quantitative analysis of the grain amyloplast proteome reveals differences in metabolism between two wheat cultivars at two stages of grain development

BMC Genomics, 2018
Background Wheat (Triticum aestivum L.) is one of the world’s most important grain crops. The amyloplast, a specialized organelle, is the major site for starch synthesis and storage in wheat grain.
Dongyun Ma, Xin Huang, Junfeng Hou, Ying Ma, Qiaoxia Han, Gege Hou, Chenyang Wang, Tiancai Guo   +7 more
doaj   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Percutaneous coronary intervention for patients with type 2 diabetes mellitus: risks and novel way to manage

Сахарный диабет, 2019
The article is a literature review devoted to issues of planned percutaneous coronary intervention for patients with type 2 diabetes mellitus. Pathogenetic base of poor prognosis and new ways to pharmacological risk correction are described.
Anastasia M. Kochergina, Alina A. Khorlampenko   +1 more
doaj   +1 more source

Printing Nacre‐Mimetic MXene‐Based E‐Textile Devices for Sensing and Breathing‐Pattern Recognition Using Machine Learning

Advanced Functional Materials, EarlyView.
This study presents a Ti3C2Tx MXene/WPU nacre‐mimetic nanomaterial as a printable ink for direct‐write printing onto textiles‐based sensors. The resulting wearable device demonstrates high sensitivity, biocompatibility, and mechanical strength. Furthermore, NFC‐enabled humidity sensor produces time‐series data, which informs a machine learning ...
Lulu Xu, Wenqing Chen, Qian Li, Rohit Gupta, Biswajoy Bagchi, Laurence B. Lovat, Manish K. Tiwari   +6 more
wiley   +1 more source

Carbohydrate metabolism in patients with erysipelas

Український журнал клінічної хірургії
Objective. To determine the frequency of erysipelas and the frequency of carbohydrate metabolism disorders in patients of the purulent–septic centre in Zaporizhzhya. Materials and methods.
С. D. Shapoval, L. A. Vasilevska
doaj   +1 more source

Association of polymorphism of some candidate genes of lipid and carbohydrate metabolism with anthropometric indices and inflammatory markers in patients with type 2 diabetes mellitus in the population of Azerbaijan

Ожирение и метаболизм, 2012
The purpose of the study was to analyze the association of gene polymorphisms of leptin, adiponectin, tumor necrosis factor alpha (TNF-α), insulin-induced gene, and the parameters of carbohydrate and lipid metabolism, level of C-reactive protein (CRP) in

doaj   +1 more source