Results 61 to 70 of about 1,914,451 (383)

Diabetes Mellitus : Insulin use [PDF]

open access: yes, 2003
Insulin is required for normal carbohydrate, protein and fat metabolism. Patients with Type I diabetes depend on exogenous insulin for their survival while Type II diabetics may require insulin at a later stage of their disease.peer ...
Tonna, Antonella
core  

A pivotal role for starch in the reconfiguration of 14C-partitioning and allocation in Arabidopsis thaliana under short-term abiotic stress. [PDF]

open access: yes, 2018
Plant carbon status is optimized for normal growth but is affected by abiotic stress. Here, we used 14C-labeling to provide the first holistic picture of carbon use changes during short-term osmotic, salinity, and cold stress in Arabidopsis thaliana ...
A Graf   +66 more
core   +2 more sources

Difficulties in differential diagnosis of carbohydrate metabolism disorders in patients with coronavirus infection in real clinical practice. Case report

open access: yesConsilium Medicum, 2023
The problem of the impact of coronavirus infection on carbohydrate metabolism remains open. In the course of the disease, various disorders of carbohydrate metabolism are detected, including newly diagnosed diabetes mellitus and transient hyperglycemia ...
Tatyana N. Markova   +3 more
doaj   +1 more source

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

open access: yesFEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez   +3 more
wiley   +1 more source

Cats and Carbohydrates: The Carnivore Fantasy?

open access: yesVeterinary Sciences, 2017
The domestic cat’s wild ancestors are obligate carnivores that consume prey containing only minimal amounts of carbohydrates. Evolutionary events adapted the cat’s metabolism and physiology to this diet strictly composed of animal tissues and led to ...
Adronie Verbrugghe, Myriam Hesta
doaj   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

On the accessibility of adaptive phenotypes of a bacterial metabolic network [PDF]

open access: yes, 2009
The mechanisms by which adaptive phenotypes spread within an evolving population after their emergence are understood fairly well. Much less is known about the factors that influence the evolutionary accessibility of such phenotypes, a pre-requisite for their emergence in a population.
arxiv   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Profile of Cardiovascular Risk Factors in Ischemic Heart Disease in Patients with Normal and Impaired Carbohydrate Metabolism

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2016
Aim of investigation — to conduct the comparative analysis of profile of general population cardiovascular risk factors in patients with ischemic heart disease (IHD) on a background of normal and impaired carbohydrate metabolism.
І.V. Cherniavska
doaj   +1 more source

Radical-free hyperpolarized MRI using endogenously-occurring pyruvate analogues and UV-induced nonpersistent radicals [PDF]

open access: yes, 2020
It was demonstrated that nonpersistent radicals can be generated in frozen solutions of metabolites such as pyruvate by irradiation with ultraviolet (UV) light, enabling radical-free dissolution DNP. Although pyruvate is endogenous, an excess of additional pyruvate may perturb metabolic processes, making it potentially unsuitable as a polarizing agent ...
arxiv   +1 more source

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