Results 91 to 100 of about 173,753 (285)

Liver fibrosis and markers of endothelial function at metabolic syndrome and early disorders of carbohydrate metabolism

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии, 2014
Aim of investigation. Complex estimation of endothelial function at non-alcoholic fatty liver disease (NAFLD) in association with early disorders of carbohydrate metabolism, in relation to liver fibrosis severity.Material and methods. Overall 67 patients
L. V. Chesnokova   +4 more
doaj  

Chaperone Mediated Autophagy in the Crosstalk of Neurodegenerative Diseases and Metabolic Disorders

open access: yesFrontiers in Endocrinology, 2019
Chaperone Mediated Autophagy (CMA) is a lysosomal-dependent protein degradation pathway. At least 30% of cytosolic proteins can be degraded by this process. The two major protein players of CMA are LAMP-2A and HSC70. While LAMP-2A works as a receptor for
Iván E. Alfaro   +9 more
doaj   +1 more source

Toward eradication of B-vitamin deficiencies : considerations for crop biofortification [PDF]

open access: yes, 2018
'Hidden hunger' involves insufficient intake of micronutrients and is estimated to affect over two billion people on a global scale. Malnutrition of vitamins and minerals is known to cause an alarming number of casualties, even in the developed world ...
Strobbe, Simon   +1 more
core   +3 more sources

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

open access: yesAdvanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija   +22 more
wiley   +1 more source

Hearing Loss, Dizziness, and Carbohydrate Metabolism

open access: yesInternational Archives of Otorhinolaryngology, 2015
Introduction Metabolic activity of the inner ear is very intense, and makes it sensitive to changes in the body homeostasis. This study involves a group of patients with inner ear disorders related to carbohydrate metabolism disturbances, including ...
Pedro L. Mangabeira Albernaz
doaj   +1 more source

Peculiarities of carbohy drate metabolism of patients with arterial hypertension against the background of abdominal obesity depending on Pro197Leu polymorphism of the GPX1 gene [PDF]

open access: yes, 2013
Pro197Leu polymorphism of the gene GPX1 in 102 patients with arterial hypertension and concomitant abdominal obesity and 97 healthy individuals have been studied.
Abramova, N.O., Pashkovska, N.V.
core  

Nonalcoholic steatohepatitis pharmacotherapy and predictors of response: dual role of aminotransferases as biosensors of metabolism and biomarkers of histological improvement [PDF]

open access: yes, 2019
Nonalcoholic steatohepatitis (NASH)—the severe histological form of nonalcoholic fatty liver disease (NAFLD)—is regarded as a major health problem worldwide (1,2).
Pirola, Carlos José   +1 more
core   +1 more source

Time‐Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism

open access: yesAdvanced Science, EarlyView.
This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia   +5 more
wiley   +1 more source

The prevalence of type 2 diabetes and glucose intolerance in the adult population of the Moscow region

open access: yesОжирение и метаболизм, 2008
Currently in Russia, as well as throughout the world, has been steadily increasing prevalence of type 2 diabetes and early disorders of carbohydrate metabolism - impaired glucose tolerance and impaired fasting glucose.
A V Dreval'   +4 more
doaj   +1 more source

In vitro screening of probiotic lactic acid bacteria and prebiotic glucooligosaccharides to select effective synbiotics [PDF]

open access: yes, 2010
Probiotics and prebiotics have been demonstrated to positively modulate the intestinal microflora and could promote host health. Although some studies have been performed on combinations of probiotics and prebiotics, constituting synbiotics, results on ...
Courtin, Céline   +6 more
core   +2 more sources

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