Results 111 to 120 of about 2,431,689 (244)

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Developing Metal–Polyphenol Network‐Based Single‐Protein Particle Encapsulation System for Sustained Release of Whey Protein to Mitigate Sarcopenia

Advanced Science, EarlyView.
Sarcopenia has emerged as a major health challenge in the aging population. Developing a sustained‐release system for whey protein may enhance its effectiveness in mitigating sarcopenia. Herein, a novel “single‐protein particle encapsulation” (SPPE) system is developed to protect whey protein and control its release.
Yafei Zhang, Yuning Zhang, Yongjian Ai, Yao Lu, Heng Quan, Zhen Zhang, Yuqi Wang, Yujia Luo, Xiaoxu Zhang, Yingying Lin, Sijia Song, Huiyuan Guo   +11 more
wiley   +1 more source

Protein and carbohydrate metabolism disorders in patients with malignant tumors of the intestine

, 2018
Представлены результаты исследования нарушений белкового и углеводного обмена у первичных больных с местнораспространенным колоректальным раком. Установлен дисбаланс как незаменимых, так и заменимых аминокислот, а также глубокие нарушения углеводного ...
Поповская, Т.Н., Жуков, В.И., Перепадя, С.В.   +2 more
core  

Galactokinase 1 Positively Regulates Mitochondrial Respiration by Phosphorylating TIMM13 as a Protein Kinase

Advanced Science, EarlyView.
GALK1 acts as a protein kinase beyond the phosphorylation of galactose. GALK1 phosphorylates TIMM13 at Y73 in the cytoplasm. This phosphorylation prevents premature oxidative folding of TIMM13 and ensures its entrance into the intermembrane space of mitochondrion, positively regulating mitochondrial respiration.
Chang Woo Ko, Dongyoon Shin, Junho Park, June Huh, Youngsoo Kim, Jong‐Wan Park   +5 more
wiley   +1 more source

Omnidirectional Interaction Networks Modulating Phenotypic Plasticity in the Gut Microbiota Towards Ulcerative Colitis

Advanced Science, EarlyView.
This study employs a spouse‐pair cohort design and an idopNetwork model that integrates evolutionary game theory, predator‐prey dynamics, and developmental modularity theory to reconstruct maximally informative microbial interaction networks. This approach reveals how interspecies interactions drive the phenotypic plasticity of the gut microbiota in ...
Huizhen Li, Jiayi Li, Ang Dong, Xiaoyan Guo, Qiuyue Tu, Zelin Feng, Haojia Lin, Yanru Zhang, Yuxuan Hao, Huiying Gong, Yihan Meng, Yu Wang, Shing‐Tung Yau, Xiaocang Cao, Rongling Wu, Xinjuan Liu   +15 more
wiley   +1 more source

GLYCOSYLATED HEMOGLOBIN AS A RISK ASSESSMENT OF THE CARDIOVASCULAR LESIONS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

Ukrainian Scientific Medical Youth Journal, 2015
Objective. Determine the prevalence of disorders of carbohydrate metabolism in study of Ukrainian population. Materials and methods. The study involved 1,148 people, which was measured by glycosylated hemoglobin The results of the study.
О. Prystupiuk
doaj  

Polypragmasy and the basics of personalized rational pharmacotherapy selection in older patients with obesity and type 2 diabetes mellitus

Ожирение и метаболизм
Increasing life expectancy and, as a consequence, a large number of comorbidities lead to a multitude of medications prescribed by physicians of different specialties.
E. A. Troshina, V. O. Barysheva, Z-Sh. R. Umarkhadzhieva   +2 more
doaj   +1 more source

Physical activity in carbohydrate metabolism status.

, 2016
Physical activity in carbohydrate metabolism status.
Elena Bordiú (2993916), Juan Girbés (2993898), Inmaculada Mora-Peces (2993910), Anna Novials (151715), Gemma Pascual-Manich (2993904), Roser Casamitjana (393119), Conxa Castell (2064136), Federico Soriguer (179748), Alfonso López-Alba (2993907), Maria Teresa Martínez-Larrad (179735), Elias Delgado (2993892), Edelmiro Menéndez (2993919), Sonia Gaztambide (2993889), Sergio Valdés (590446), Ramon Gomis (35888), Serafín Murillo (151685), Albert Goday (590445), Rafael Carmena (2993895), Alfonso Calle-Pascual (2993901), Anna Bosch-Comas (263923), Joan Vendrell (293277), Luis Castaño (193656), Laura Brugnara (151680), Emilio Ortega (637366), Miguel Catalá (2993922), Gemma Rojo-Martínez (216786), Josep Franch (2993913), Manuel Serrano-Ríos (179755)   +27 more
core   +1 more source

A Postbiotic‐Inducing Ganoderma applanatum Polysaccharide Repairs the Intestinal Barrier via a Phocaeicola vulgatus ‐ Tridecylic Acid Axis

Advanced Science, EarlyView.
This study identifies GAP2, a bioactive polysaccharide fraction derived from Ganoderma applanatum, as a postbiotic inducer that repairs intestinal barrier damage in a gut microbiota‐dependent manner. GAP2 enriches Phocaeicola vulgatus, which degrades GAP2 and promotes tridecylic acid production, triggering Rho/CDC42 signaling and tight‐junction ...
Chuan Zhang, Miaoyu Li, Tiantian Li, Xiaojie Zang, Haiyang Shi, Yaru Liu, Chengcheng Zhang, Jianxin Zhao, Qixiao Zhai, Wei Chen, Fengwei Tian   +10 more
wiley   +1 more source

Determination of Gene‐Level Fitness Contributions Across the Mucin‐Utilization Network of Bacteroides thetaiotaomicron

Advanced Science, EarlyView.
Genome‐wide CRISPRi and RNA‐seq resolve how B. thetaiotaomicron converts host mucosal glycans into fitness. The study reveals a layered mucin‐utilization architecture in which capsular polysaccharides constrain surface access, extracellular CAZymes and peptidases show functional redundancy, and intracellular catabolic pathways create discrete metabolic
Kangsan Kim, Jiwon Lee, Minjeong Kang, Sung Sun Yim, Donghui Choe, Byung‐Kwan Cho   +5 more
wiley   +1 more source