Results 131 to 140 of about 2,431,689 (244)

Astrocytic Ketogenesis Protects Central Nervous System Injury via CPT1A Stabilization and Epigenetic Regulation

open access: yesAdvanced Science, EarlyView.
A distinct astrocyte subpopulation, enriched at the lesion border, drives CNS repair through enhanced ketone body metabolism. This process promotes neuronal survival and axonal sparing via CPT1A stabilization and H3K9bhb‐dependent epigenetic reprogramming, positioning astrocytic ketogenesis as a promising therapeutic target for tissue regeneration ...
Dishui Pan   +14 more
wiley   +1 more source

Soft Interactions, Rather Than Crowder Size, Determine Deviations From Arrhenius‐Like Kinetics of Phosphofructokinase‐1

open access: yesAngewandte Chemie, EarlyView.
Our study investigates macromolecular crowding effects in the Arrhenius‐like and non‐Arrhenius temperature regimes of the human platelet isoform of phosphofructokinase‐1 (PFKP). The results reveal how PFKP maintains temperature robustness of catalytic activity in differently crowded environments.
Harshita Rastogi   +7 more
wiley   +2 more sources

Polymorphism of the GLIS3 gene in a Caucasian population and among individuals with carbohydrate metabolism disorders in Russia. [PDF]

open access: yesBMC Res Notes, 2018
Shakhtshneider EV   +7 more
europepmc   +1 more source

Rational Surface Engineering Reduces Advanced Glycation End‐Product Adsorption and Improves Implant Integration

open access: yesAdvanced Science, EarlyView.
Targeted surface chemical modification prevents the accumulation of advanced glycation end products (AGEs) on implant surfaces, attenuates inflammation and fibrosis, effectively restores angiogenic activity, and improves osseointegration under diabetic conditions.
Thien Ngoc Le   +13 more
wiley   +1 more source

Promoting Healthier Drinking: Evidence From a Vignette Experiment on Contextual and Informational Drivers of Dealcoholized Wine Choices

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT Growing demand for healthier beverages is driving innovation in the wine sector, with dealcoholized wine emerging as a promising alternative. However, little is known about the contextual conditions under which consumers would choose dealcoholized wine, particularly in countries with strong wine traditions. To fill this gap, this work examines
Giovanna Piracci   +4 more
wiley   +1 more source

Self‐Assembled Pt(II) Complexes Boost Up Stem Cell Proliferation and Accelerate Metamorphosis in Living Organisms

open access: yesAngewandte Chemie, EarlyView.
Pt1, an organometallic platinum‐based complex, act as a modulator of redox homeostasis in cnidarians, regulating cellular functions and life‐cycle dynamics. In Nematostella vectensis, it mitigates oxidative stress, strengthens detox systems and accelerates development.
Giuseppina Tommasini   +13 more
wiley   +2 more sources

Sleep disorders and carbohydrate metabolism in obese patients

open access: yesСахарный диабет, 2013
N V Strueva   +3 more
doaj   +1 more source

Small Intestinal Bacterial Overgrowth Following Gastrointestinal Cancer Surgery: Current Evidence and Future Perspectives

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Small intestinal bacterial overgrowth (SIBO) has recently gained increasing attention as a potential cause of postoperative gastrointestinal symptoms following gastrointestinal cancer surgery. Surgical procedures can disrupt normal gastrointestinal physiology through anatomical reconstruction, impaired motility, reduced gastric acid secretion,
Toru Aoyama   +2 more
wiley   +1 more source

Magnetic Resonance Reveals Radical Stability in Native Biofilms and Its Role in Bacterial Resistance

open access: yesAngewandte Chemie, EarlyView.
The complex biofilm environment consists of planktonic bacterial cells and cells embedded in an extracellular matrix (ECM). Through an integrated magnetic resonance approach, we show that nitroxide radicals primarily interact with the polysaccharides and lipids in the ECM.
Alysia Mandato   +10 more
wiley   +2 more sources

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