Results 151 to 160 of about 257,841 (286)

NFS1 Regulates IDH2 to Attenuate Abdominal Aortic Aneurysms via Interacting With SP2

open access: yesAdvanced Science, EarlyView.
The loss of NFS1 leads to its reduced binding with the transcription factor SP2, resulting in decreased expression of the downstream gene Idh2. This causes a shift in energy supply toward glycolysis in VSMCs, ultimately contributing to the occurrence and progression of AAA.
Luzheng Zhang   +9 more
wiley   +1 more source

Top‐Down Fabricated Wood‐Derived Pressure and Strain Sensors: A Review

open access: yesAdvanced Science, EarlyView.
This review focuses on wood‐derived pressure/strain sensors fabricated via top‐down strategies. It analyzes wood's structural composition, examines processing techniques, discusses sensor types and sensing mechanisms, and reviews existing research. The article concludes with future directions for enhancing performance and scalability.
Yi Ren   +8 more
wiley   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

open access: yesAdvanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen   +11 more
wiley   +1 more source

Efeito da dieta cetogênica na capacidade de endurance e na utilização de substratos energéticos no exercício

open access: yesRevista Brasileira de Nutrição Esportiva, 2018
O objetivo desta revisão foi identificar e discutir evidências científicas sobre os efeitos da dieta cetogênica com severa restrição de carboidrato na capacidade de endurance e em metabólicas no exercício em indivíduos saudáveis. Realizou-se uma busca de
Cristiane Oliveira de Abreu Perroni   +2 more
doaj  

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

open access: yesAdvanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu   +13 more
wiley   +1 more source

O2-H2O2 high-efficient co-oxidation of carbohydrate biomass to formic acid via Co3O4/C nanocatalyst

open access: yesCarbon Neutrality
The conversion of biomass to chemicals/fuels has emerged as a valuable solution that offers both environmental and economic benefits, with the transformation of carbohydrate into formic acid garnering escalating scholar interest.
Yujie Chen   +3 more
doaj   +1 more source

Regioselective oxidation of carbohydrates

open access: yes, 2017
This thesis describes the further developments of the palladium catalysed selective oxidation of carbohydrates. With this method, it is possible to selectively oxidize the alcohol functionality on the C3 position in a range of glucosides (glucose like sugars).
openaire   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

open access: yesAdvanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang   +12 more
wiley   +1 more source

Does mental exertion during incremental exercise change substrate oxidation and cardiorespiratory outcomes in individuals with overweight?

open access: yesPhysiological Reports
Given the growing concern over the impact of brain health in individuals with overweight, understanding how mental exertion (ME) during exercise affects substrate oxidation and cardiorespiratory outcomes is crucial.
Samira Pourmirzaei Kouhbanani   +2 more
doaj   +1 more source

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