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Modeling Protein Recognition of Carbohydrates
Proteins: Structure, Function and Bioinformatics, 2005AbstractWe have a limited understanding of the details of molecular recognition of carbohydrates by proteins, which is critical to a multitude of biological processes. Furthermore, carbohydrateâmodifying proteins such as glycosyl hydrolases and phosphorylases are of growing importance as potential drug targets.
Alain Laederach, Peter J Reilly
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Organizing Multivalency in Carbohydrate Recognition
Chemical Society Reviews, 2016 The interactions of cell surface carbohydrates as well as of soluble glycoconjugates with their receptor proteins rule fundamental processes in cell biology. One of the supramolecular principles underlying and regulating carbohydrate recognition is multivalency.
Thisbe Lindhorst, Guillaume Despras
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Carbohydrates in Cell Recognition
Scientific American, 1993Telltale surface sugars enable cells to identify and interact with one another. New drugs aimed at those carbohydrates could stop infection and inflammation.
N, Sharon, H, Lis
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Aptamer-Based Carbohydrate Recognition.
Current Pharmaceutical Design, 2010Carbohydrates have been revealed to play fundamental roles in diverse biological phenomena, such as being recognition sites and biomarkers. Recently, ample nucleic acid aptamers guided for carbohydrate recognition have already been isolated and characterized through SELEX methodology.
Lupei Du, Minyong Li
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Carbohydrate-Recognition and Angiogenesis
Cancer and Metastasis Reviews, 2000Angiogenesis is required for the continual growth of the tumor and provides a gateway for cells to escape the confines of the primary tumor. Angiogenic stimulus triggers a cascade of functional responses leading to local basement membrane dissolution, endothelial cell migration, proliferation and microvessel morphogenesis. In this commentary, we review
P, Nangia-Makker, S, Baccarini, A, Raz
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Chemistry - A European Journal, 2001
The synthesis and binding properties for carbohydrates of several artificial, acyclic receptors containing two or three heterocyclic recognition units covalently attached to a phenyl spacer is described. These host molecules having uncharged hydrogen-bonding sites were used in a systematic study towards the evaluation of recognition motifs for ...
Monika Mazik
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The synthesis and binding properties for carbohydrates of several artificial, acyclic receptors containing two or three heterocyclic recognition units covalently attached to a phenyl spacer is described. These host molecules having uncharged hydrogen-bonding sites were used in a systematic study towards the evaluation of recognition motifs for ...
Monika Mazik
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