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A general and sensitive chemical method for sequencing the glycosyl residues of complex carbohydrates

Carbohydrate Research, 1980
This paper describes a new glycosyl-sequencing method. This method was made possible by the ability to fractionate complex mixtures of peralkylated oligosaccharides by reversed-phase, high-pressure liquid chromatography. The fractionation ability of the reversed-phase system allows the isolation and subsequent unambiguous identification by g.l.c.-m.s ...
B S, Valent   +4 more
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The double‐DANTE sequence applied to NMR of complex carbohydrates

Magnetic Resonance in Chemistry, 1991
AbstractThe double‐DANTE sequence was implemented in 1D TOCSY and NOESY experiments to overcome some typical problems in the NMR of carbohydrates. In the 1D TOCSY experiment the double‐DANTE sequence serves to invert simultaneously two resonances belonging to the same scalar‐coupled spin system, thereby substantially increasing the sensitivity of the ...
Leszek Poppe, Herman van Halbeek
openaire   +1 more source

Human Urinary Kallikrein: Amino Acid Sequence and Carbohydrate Attachment Sites

1989
The amino acid sequence of human urinary kallikrein was determined by protein-chemical methods. The peptide chain contains 238 amino acid residues. Ten half-cystine residues form five disulfide bridges. Six carbohydrate side chains could be identified, three of them are N-glycosidically linked to asparagine which is present in the acceptor sequon Asn ...
J, Kellermann   +3 more
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Handling and Conversion of Carbohydrate Sequence Formats and Monosaccharide Notation

2015
Various glycobioinformatics resources have developed individual carbohydrate sequence formats to store and handle glycan data. This diversity of sequence formats is one of the major reasons for a rather low interoperability of glycobioinformatics resources.
openaire   +2 more sources

Carbohydrate antigen expression in the adenoma-carcinoma sequence.

Progress in clinical and biological research, 1988
Several alterations in carbohydrate antigen expression can occur in colon cancers. Modified structures such as extended LeX and LeY antigens could serve as cancer-associated antigens in the human colon, although none is specific only for colon cancer.
Y S, Kim, S H, Itzkowitz
openaire   +1 more source

Glycoprofiling by DNA Sequencer-Aided Fluorophore-Assisted Carbohydrate Electrophoresis

2007
In recent years, the importance of glycosylation has been realized. Carbohydrates not only serve as decoration for proteins and lipids but also form an integral part of the glycoconjugate, adding to its functional and structural properties. The specific type of glycosylation may change with altering physiological conditions, such as disease.
Wouter Laroy, Roland Contreras
openaire   +1 more source

Protein and carbohydrate sequence analysis

1975
R. A. W. Johnstone   +2 more
openaire   +1 more source

Proteins Binding to the Carbohydrate HNK-1: Common Origins?

International Journal of Molecular Sciences, 2021
Gaston Castillo   +2 more
exaly  

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