Results 241 to 250 of about 309,097 (345)
Carbohydrate sequence of the prostate cancer-associated antigen F77 assigned by a mucin O-glycome designer array. [PDF]
Gao C+15 more
europepmc +1 more source
Long Term High‐Salt Diet Induces Cognitive Impairments via Down‐Regulating SHANK1
The study identifies a novel mechanistic link between long‐term HS diet and cognitive impairment, wherein PKA/CREB axis inactivation leads to SHANK1 reduction, synaptic damage, and cognitive deficits. Abstract High‐salt (HS) diet is an established risk factor for cognitive impairment, but the underlying mechanisms remain unclear.
Cuiping Guo+10 more
wiley +1 more source
Whole genome sequence data of <i>Pediococcus pentosaceus</i> NIBL1955 isolated from rice. [PDF]
Yoon JA+5 more
europepmc +1 more source
TBC1D22B, a Golgi‐localized RabGAP linked to poor prognosis in breast cancer, inhibits ER‐to‐Golgi transport via RAB1B inactivation. This disrupts secretion, drives oncogenic transcriptional reprogramming, and promotes tumor growth. These findings indicate that TBC1D22B connects membrane trafficking to transcriptional control and cancer progression ...
Flavia Martino+16 more
wiley +1 more source
An l-fucose-responsive transcription factor cross-regulates the expression of a diverse array of carbohydrate-active enzymes in Trichoderma reesei. [PDF]
Zhao Q+6 more
europepmc +1 more source
Epigenetic Regulation of DAPK1 and Netrin‐1 Drives Diabetic Encephalopathy
This study identifies a microRNA (miR)‐216a‐5p/death‐associated protein kinase 1 (DAPK1)/hepatocyte nuclear factor 1 homeobox A (HNF1A)/Netrin‐1 signaling axis in diabetic encephalopathy (DE). In leptin receptor‐deficient (db/db) and streptozotocin (STZ)‐induced diabetic mice, reduced miR‐216a‐5p increases DAPK1 expression, disrupting HNF1A binding to ...
Yang Zhou+14 more
wiley +1 more source
Identification and Sequence Comparison of Carbohydrate Oxidase Enzyme from Plant Sources
Jennifer A. Maki, Kaitlyn Daggett
openaire +2 more sources
Acute restraint stress enhances STAT3Ser727 phosphorylation in dopaminergic neurons in mice. This modification promotes the upregulation of GABBR2 and GABRB3, reduces neuronal activity, and contributes to anxiety‐like behavior and diminished reward‐seeking following stress exposure.
Mingshuo Shao+10 more
wiley +1 more source