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CabosDB: Carbohydrate Sequencing Database [PDF]

open access: possible, 2009
High-throughput methods for sequencing biomolecules such as DNA, RNA and proteins, and for profiling their patterns of expression have accelerated genome-wide analyses in living organisms. Further, they have enabled molecular biologists and biochemists to investigate biological functions and disorders, the so-called -omics studies. Glycomics, which has
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Carbohydrate-active enzymes: sequences, shapes, contortions and cells

Biochemical Society Transactions, 2016
The enzyme-catalysed degradation of oligo and polysaccharides is of considerable interest in many fields ranging from the fundamental–understanding the intrinsic chemical beauty–through to the applied, including diverse practical applications in medicine and biotechnology.
Spencer J. Williams, Gideon J. Davies
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LINUCS: LInear Notation for Unique description of Carbohydrate Sequences

Carbohydrate Research, 2001
The use of proteomics databases has become indispensable for daily work of molecular biologists, but this situation has not yet been achieved for carbohydrate applications. One obvious reason is that existing data collections are only rarely annotated and no cross-linking to other resources exists.
Elke Lang   +3 more
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Sequencing methods for carbohydrates and their biological applications

Trends in Biotechnology, 1989
Abstract The diversity of oligosaccharide structures may confer the specificity inherent in many molecular and cellular interactions. Scientists from numerous disciplines are faced with the challenge of determining their sequence and deciphering their function.
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Sequence-Specific Peptide−Carbohydrate Interactions in an Asparagine-Linked Glycopeptide

The Journal of Organic Chemistry, 1996
Asparagine glycosylation (N-glycosylation) of the AsnXaa-Ser/Thr sequence is a cotranslational process that can affect protein structure and function.1,2 Little is known, however, about glycosylation’s influence on the structure of flexible N-glycopeptides.3-7 Fluorescence studies show that N-glycosylation can alter peptide backbone conformation.6 ...
Jeffery T. Davis   +2 more
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Use of mass spectrometry for the carbohydrate composition and sequence analysis of glycosphingolipids

Biological Mass Spectrometry, 1974
Mass spectrometry has been applied for a detailed structural characterization of glycosphingolipids. Methylated and methylated plus reduced glycolipids (amide groups of ceramide and amino sugars were reduced to the corresponding amines) were found the most useful derivatives.
I. Pascher   +3 more
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Carbohydrate sequences detected by murine monoclonal antibodies

Chemistry and Physics of Lipids, 1986
The carbohydrate sequences of cell surface glycolipids change during differentiation and oncogenic transformation. To detect these structural changes, murine monoclonal antibodies have been produced in many different laboratories. Some of these antibodies are used to distinguish various cell types such as normal and transformed cells, while others are ...
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The double‐DANTE sequence applied to NMR of complex carbohydrates

Magnetic Resonance in Chemistry, 1991
AbstractThe double‐DANTE sequence was implemented in 1D TOCSY and NOESY experiments to overcome some typical problems in the NMR of carbohydrates. In the 1D TOCSY experiment the double‐DANTE sequence serves to invert simultaneously two resonances belonging to the same scalar‐coupled spin system, thereby substantially increasing the sensitivity of the ...
Leszek Poppe, Herman van Halbeek
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A general and sensitive chemical method for sequencing the glycosyl residues of complex carbohydrates

Carbohydrate Research, 1980
This paper describes a new glycosyl-sequencing method. This method was made possible by the ability to fractionate complex mixtures of peralkylated oligosaccharides by reversed-phase, high-pressure liquid chromatography. The fractionation ability of the reversed-phase system allows the isolation and subsequent unambiguous identification by g.l.c.-m.s ...
Børre K. Robertsen   +4 more
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The carbohydrate-binding sequences in lectins of the clovers Trifolium repens, T. pratense, and T. trichocephalum

Russian Journal of Genetics, 2007
The carbohydrate-binding sequences (CBS) in the lectin genes of Trijilium repens, T. pratense, and T. tri-chocephalum were sequenced. The gene regions encoding lectin CBS of T. pratense and T. repens displayed a considerable similarity; however, the CBS of these species differed essentially. Moreover, T.
A. V. Chemeris   +3 more
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