Results 61 to 70 of about 382,516 (375)

Identification of Carbohydrate Metabolism Genes in the Metagenome of a Marine Biofilm Community Shown to Be Dominated by Gammaproteobacteria and Bacteroidetes [PDF]

, 2010
Polysaccharides are an important source of organic carbon in the marine environment and degradation of the insoluble and globally abundant cellulose is a major component of the marine carbon cycle.
Connolly, John, Cox, Michael, Edwards, Clive, Edwards, Jennifer, Joint, Ian, McCarthy, Alan, McDonald, James, Smith, Darren   +7 more
core   +2 more sources

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

FEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva, Marcio Vinicius Bertacine Dias   +1 more
wiley   +1 more source

Nutrients and biomass dynamics in photo-sequencing batch reactors treating wastewater with high nutrients loadings [PDF]

, 2018
The present study investigates different strategies for the treatment of a mixture of digestate from an anaerobic digester diluted and secondary effluent from a high rate algal pond. To this aim, the performance of two photo-sequencing batch reactors (PSBRs) operated at high nutrients loading rates and different solids retention times (SRTs) were ...
arxiv   +1 more source

Anomeric memory of the glycosidic bond upon fragmentation and its consequences for carbohydrate sequencing [PDF]

Nature Communications, 2017
AbstractDeciphering the carbohydrate alphabet is problematic due to its unique complexity among biomolecules. Strikingly, routine sequencing technologies—which are available for proteins and DNA and have revolutionised biology—do not exist for carbohydrates.
Stéphane Chambert, Stéphane Chambert, Loïc Barnes, Sébastien Fort, Sébastien Fort, Abdul-Rahman Allouche, Baptiste Schindler, Gina Predelus Renois, Sabine L. Flitsch, Isabelle Compagnon, Christopher J. Gray, Claire Loison   +11 more
openaire   +6 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

De novo assembly and characterization of the transcriptome of a wild edible mushroom Leucocalocybe mongolica and identification of SSR markers

Biotechnology & Biotechnological Equipment, 2017
Leucocalocybe mongolica is a prestigious rare wild edible mushroom in Northeast Asia. It is the unique species of the genus and the studying of its phynotype and genome is crucial to genus and species classification.
Tie Lu, Tolgor Bau
doaj   +1 more source

Graph theoretic methods for the analysis of structural relationships in biological macromolecules [PDF]

, 2005
Subgraph isomorphism and maximum common subgraph isomorphism algorithms from graph theory provide an effective and an efficient way of identifying structural relationships between biological macromolecules.
Altschul, Artymiuk, Artymiuk, Artymiuk, Artymiuk, Artymiuk, Barnard, Baxevanis, Benning, Berman, Bernstein, Brint, Brint, Bron, Bruno, Bryant, Crandell, Dean, Diestel, Doubet, Fan, Feizi, Figueras, Flores, Gardiner, Gati, Good, Gray, Groves, Gruer, Gund, Hagadone, Harrison, Holden, Hutchinson, Jasanoff, Johnson, Kanna, Klausner, Kleywegt, Koch, Kraulis, Lengauer, Lesk, Martin, Martin, McGregor, Messmer, Mitchell, Ollis, Pickering, Ray, Raymond, Read, Salton, Samudrala, Sayle, Simon, Srere, Sussenguth, Tesmer, Tinoco, Trinajstic, Tsukada, Ullmann, van Rijsbergen, Willett, Willett, Willett, Willett, Williams, Wilson, Zhang   +72 more
core   +3 more sources

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

FEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Crystal Structure of the Cysteine-Rich Domain of Mannose Receptor Complexed with a Sulfated Carbohydrate Ligand [PDF]

, 2000
The macrophage and epithelial cell mannose receptor (MR) binds carbohydrates on foreign and host molecules. Two portions of MR recognize carbohydrates: tandemly arranged C-type lectin domains facilitate carbohydrate-dependent macrophage uptake of ...
Bjorkman, Pamela J., Chirino, Arthur J., Feizi, Ten, Leteux, Christine, Liu, Yang, Misulovin, Ziva, Nussenzweig, Michel C.   +6 more
core   +2 more sources

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

FEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti, Sebastian Obermaier, Dirk J. Slotboom, Bert Poolman   +3 more
wiley   +1 more source