Results 51 to 60 of about 1,004,004 (297)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
, 2015 © 2015 Springer-Verlag Berlin Heidelberg.Rationale: Central modulation of serotonin and dopamine underlies efficacy for a variety of psychiatric therapeutics.
Bisuna, B +13 more
core +1 more source
Synthesis of 11C-Labelled Ureas by Palladium(II)-Mediated Oxidative Carbonylation
Molecules, 2017 Positron emission tomography is an imaging technique with applications in clinical settings as well as in basic research for the study of biological processes.
Sara Roslin +5 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Classic and local analysis of corrosion behaviour of graphite and stainless steels in polluted phosphoric acid [PDF]
, 2006 In phosphoric acid solution (40% H3PO4), the corrosion behaviour of graphite and stainless steels was studied by the use of different electrochemical methods, namely polarization curve analysis, electrochemical impedance spectroscopy (EIS) and scanning ...
Basséguy, Régine +3 more
core +1 more source
Eurasian Chemico-Technological Journal, 2020 The microporous polyvinylidene fluoride (PVDF) membranes were prepared by the solvent evaporation method using 50 wt.% of different pore-forming additives: poly(1-ethyl-3-vinylimidazolium tetrafluoroborate) (PIL-BF4), polyethylene glycol 3000 (PEG-3K ...
O. S. Morozov +4 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Ethanolic carbon-11 chemistry: the introduction of green radiochemistry. [PDF]
Appl Radiat Isot, 2014 The principles of green chemistry have been applied to a radiochemistry setting. Eleven carbon-11 labeled radiopharmaceuticals have been prepared using ethanol as the only organic solvent throughout the entire manufacturing process. The removal of all other organic solvents from the process simplifies production and quality control (QC) testing, moving
Shao X, Fawaz MV, Jang K, Scott PJ.
europepmc +4 more sources
In vivo imaging of cellular proliferation in colorectal cancer using positron emission tomography [PDF]
, 2003 Background and aims: Positron emission tomography (PET) using 18F labelled 2-fluoro-2-deoxy-D-glucose (18FDG) is an established imaging tool, although the recent development of a biologically stable thymidine analogue [18F] 3'-deoxy-3-fluorothymidine ...
Costa, D.C. +7 more
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