Results 41 to 50 of about 7,863,983 (293)
Cross-Coupling Reactions as Valuable Tool for the Preparation of PET Radiotracers
Molecules, 2011 The increasing application of positron emission tomography (PET) in nuclear medicine has stimulated the extensive development of a multitude of new radiotracers and novel radiolabeling procedures with the most prominent short-lived positron emitters ...
Marc Pretze +2 more
doaj +1 more source
Nanomaterials, 2022 Ordered and disordered mesoporous structures were synthesized by a self-assembly method using a mixture of phenolic resin and petroleum-based mesophase pitch as the starting materials, amphiphilic triblock copolymer F127 as a soft template, hydrochloric ...
Jae-Yeon Yang +4 more
doaj +1 more source
, 2020 Poster presented at the ''NuPhys2019: Prospects in Neutrino Physics''
openaire +3 more sources
Huntington’s Disease: A Review of the Known PET Imaging Biomarkers and Targeting Radiotracers
Molecules, 2020 Huntington’s disease (HD) is a fatal neurodegenerative disease caused by a CAG expansion mutation in the huntingtin gene. As a result, intranuclear inclusions of mutant huntingtin protein are formed, which damage striatal medium spiny neurons (MSNs)
Klaudia Cybulska +4 more
doaj +1 more source
Decreased carbon-11-flumazenil binding in early Alzheimer's disease. [PDF]
Brain, 2012 Neuronal loss in Alzheimer's disease, a better correlate of cognitive impairment than amyloid deposition, is currently gauged by the degree of regional atrophy. However, functional markers, such as GABA(A) receptor density, a marker of neuronal integrity, could be more sensitive.
B. Pascual +8 more
semanticscholar +4 more sources
Energies, 2023 In this work, macro- and nanodiagnostic procedures for working, third-generation photovoltaic devices based on a modified polymer:fullerene (P3HT:PCBM) absorber were conducted using atomic force microscopy (AFM) and impedance spectroscopy (IS) equipment.
Marcin Palewicz +7 more
doaj +1 more source
Biochar, 2023 Biochar application combined with conservation tillage significantly increased native SOC contents and its recalcitrant proportion. Higher biochar application rates significantly enhanced C_4-derived SOC mineralization and in the growing season, biochar ...
Xinyu Ding +4 more
semanticscholar +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source