Results 31 to 40 of about 6,617,754 (307)

Adventures with Carbons 11, 12, 13 and 14 [PDF]

open access: yesPhotosynthesis Research, 2011
I provide here a glimpse of my involvement with different isotopes of carbon. In my 65 years of synthetic work with C-12, I had experience working with C-11 (one year, 1942-1943), C-13 (one year, 1999) and C-14 (67 years, 1943-2009). I have also included a postscript dealing with my 1951 communication on the 5-carbon intermediate in photosynthesis.
openaire   +2 more sources

Defense Priming in Nicotiana tabacum Accelerates and Amplifies ‘New’ C/N Fluxes in Key Amino Acid Biosynthetic Pathways

open access: yesPlants, 2020
In the struggle to survive herbivory by leaf-feeding insects, plants employ multiple strategies to defend themselves. One mechanism by which plants increase resistance is by intensifying their responsiveness in the production of certain defense agents to
Nils Hanik   +4 more
doaj   +1 more source

Pitfalls and solutions of the fully-automated radiosynthesis of [11C]metoclopramide

open access: yesEJNMMI Radiopharmacy and Chemistry, 2019
Background [11C]Metoclopramide is a new radiotracer for investigating the activity of P-glycoprotein at the blood-brain barrier. A highly stable and reproducible radiosynthesis is a prerequisite for clinical studies applying [11C]metoclopramide or other ...
Verena Pichler   +6 more
doaj   +1 more source

Non-invasive 11C-Imaging Revealed the Spatiotemporal Variability in the Translocation of Photosynthates Into Strawberry Fruits in Response to Increasing Daylight Integrals at Leaf Surface

open access: yesFrontiers in Plant Science, 2021
The efficiency of photosynthate translocation from leaves to fruits directly affects dry matter partitioning. Therefore, controlling photosynthate translocation dynamics is critical for high-yield and high-quality fruit production.
Yuta Miyoshi   +6 more
doaj   +1 more source

Ethanolic carbon-11 chemistry: the introduction of green radiochemistry. [PDF]

open access: yesAppl Radiat Isot, 2014
The principles of green chemistry have been applied to a radiochemistry setting. Eleven carbon-11 labeled radiopharmaceuticals have been prepared using ethanol as the only organic solvent throughout the entire manufacturing process. The removal of all other organic solvents from the process simplifies production and quality control (QC) testing, moving
Shao X, Fawaz MV, Jang K, Scott PJ.
europepmc   +4 more sources

Quantifying Plant-Borne Carbon Assimilation by Root-Associating Bacteria

open access: yesMicroorganisms, 2020
Herbaspirillum seropedicae is a rhizobacteria that occupies a specialized ecological niche in agriculture. As an endophyte and prolific grass root colonizer it has the potential to promote plant growth, enhancing crop yield in many cereal crops.
Spenser Waller   +4 more
doaj   +1 more source

Synthesis and Evaluation of 11C-Labeled Triazolones as Probes for Imaging Fatty Acid Synthase Expression by Positron Emission Tomography

open access: yesMolecules, 2022
Cancer cells require lipids to fulfill energetic, proliferative, and signaling requirements. Even though these cells can take up exogenous fatty acids, the majority exhibit a dependency on de novo fatty acid synthesis.
James M. Kelly   +10 more
doaj   +1 more source

Rapid one-pot radiosynthesis of [carbonyl-11C]formamides from primary amines and [11C]CO2

open access: yesEJNMMI Radiopharmacy and Chemistry, 2020
Background Formamides are common motifs of biologically-active compounds (e.g. formylated peptides) and are frequently employed as intermediates to yield a number of other functional groups.
Federico Luzi   +2 more
doaj   +1 more source

Radiolabeled COX-2 Inhibitors for Non-Invasive Visualization of COX-2 Expression and Activity — A Critical Update

open access: yesMolecules, 2013
Cyclooxygenase-2 (COX-2) is a key player in inflammation. Its overexpression is directly associated with various inflammatory diseases and, additionally, with several processes of carcinogenesis. The development of new selective COX-2 inhibitors (COXIBs)
Torsten Kniess   +2 more
doaj   +1 more source

PET Molecular Imaging in Drug Development: The Imaging and Chemistry Perspective

open access: yesFrontiers in Medicine, 2022
Positron emission tomography with selective radioligands advances the drug discovery and development process by revealing information about target engagement, proof of mechanism, pharmacokinetic and pharmacodynamic profiles. Positron emission tomography (
Sridhar Goud Nerella   +3 more
doaj   +1 more source

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