Results 11 to 20 of about 11,218 (183)

Characterisation of the Cullin-3 mutation that causes a severe form of familial hypertension and hyperkalaemia [PDF]

, 2015
Deletion of exon 9 from Cullin‐3 (CUL3, residues 403–459: CUL3Δ403–459) causes pseudohypoaldosteronism type IIE (PHA2E), a severe form of familial hyperkalaemia and hypertension (FHHt).
Al Maskari, Raya S., Cleary, Sarah E., Enchev, Radoslav, Ferryman, James T., Figg, Nichola L., Hardege, Iris, Johnson, Clare, Knebel, Axel, Kurz, Thimo, O'Shaughnessy, Kevin M., Schumacher, Frances-Rose, Siew, Keith, Wood, Nicola, Yasmin,, Zhang, Jinwei   +14 more
core   +4 more sources

Molecular characterization and analysis of the acrB gene of Aspergillus nidulans: A gene identified by genetic interaction as a component of the regulatory network that includes the CreB deubiquitination enzyme [PDF]

, 2003
Copyright © 2003 by the Genetics Society of AmericaMutations in the acrB gene, which were originally selected through their resistance to acriflavine, also result in reduced growth on a range of sole carbon sources, including fructose, cellobiose ...
Adams, J., Boase, N., Kelly, J., Lockington, R., Rodbourn, L.   +4 more
core   +1 more source

The autophagic degradation of cytosolic pools of peroxisomal proteins by a new selective pathway. [PDF]

, 2019
Damaged or redundant peroxisomes and their luminal cargoes are removed by pexophagy, a selective autophagy pathway. In yeasts, pexophagy depends mostly on the pexophagy receptors, such as Atg30 for Pichia pastoris and Atg36 for Saccharomyces cerevisiae ...
Farré, Jean-Claude, Li, Xuezhi, Ma, Changle, Subramani, Suresh, Wang, Pingping, Wang, Ruonan, Wang, Xiaofeng, Xia, Zhijie, Zhang, Zhuangzhuang   +8 more
core   +2 more sources

Improved catalytic activity of ruthenium–arene complexes in the reduction of NAD+ [PDF]

, 2012
A series of neutral Ru-II half-sandwich complexes of the type [(eta(6)-arene)Ru(N,N')Cl] where the arene is para-cymene (p-cym), hexamethylbenzene (hmb), biphenyl (bip), or benzene (bn) and N,N' is N-(2-aminoethyl) -4-(trifluoromethyl)benzenesulfonamide (
Abraha Habtemariam, Canivet J., Carrión M. C., Chen Q., Clayden J., Creutz C., Dibenedetto A., Fish R. H., Grau M. M., Grimme S., Guy J. Clarkson, Habtemariam A., Haquette P., Held M., Hileman E. O., Joan J. Soldevila-Barreda, Khan J. A., Kim Y. H., Leiva C., Li X., Lo H. C., Maenaka Y., Martins J. E. D., Matharu D. S., Matthew C. K., Morris R. E., Neese F., Noyori R., Peacock A. F. A., Peter J. Sadler, Pieter C. A. Bruijnincx, Robert J. Deeth, Robertson A., Romain C., Ruppert R., Sandoval C. A., Schäfer A., Sheldrick G. M., Sinnecker S., Tan J., Thai T., Wang C., Wang F., Watanabe M., Weckbecker A., Weigend F., Wolfson A., Wu J., Wu X., Yan Y. K., Ying W., Zhou Z., Zhou Z.   +52 more
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SUMOylation represses SnRK1 signaling in Arabidopsis [PDF]

, 2015
The SnRK1 protein kinase balances cellular energy levels in accordance with extracellular conditions and is thereby key for plant stress tolerance. In addition, SnRK1 has been implicated in numerous growth and developmental processes from seed filling ...
Bachmair, Andreas, Baena-González, Elena, Butowt, Rafal, Crozet, Pierre, Elias, Carlos A., Fernandes, Noémia, Margalha, Leonor, Orosa, Beatriz, Sadanandom, Ari, Teige, Markus, Tomanov, Konstantin   +10 more
core   +1 more source

Zinc accumulation and utilisation by wine yeasts [PDF]

, 2009
The present study has focused on the accumulation of zinc by wine yeast strains of Saccharomyces cerevisiae during fermentation of both grape juice and chemically defined medium with different carbohydrates and at varying levels of zinc. The results have
Bollag, Tatiana, De Nicola, Raffaele, Hall, Nichola, Thermogiannis, Georgios, Walker, Graeme M.   +4 more
core   +2 more sources

Mechanistic insight into acrylate metabolism and detoxification in marine dimethylsulfoniopropionate-catabolizing bacteria [PDF]

, 2017
Dimethylsulfoniopropionate (DMSP) cleavage, yielding dimethyl sulfide (DMS) and acrylate, provides vital carbon sources to marine bacteria, is a key component of the global sulfur cycle and effects atmospheric chemistry and potentially climate.
Adams, Alcolombri, Archer, Asao, Baldwin, Biebl, Brummett, Brummett, Clayden, Conti, Curson, Curson, Curson, Curson, Ducruix, Elssner, Emsley, Gulick, Gulick, Herrmann, Hisanaga, Horswill, Jackson, Jogl, Khare, Kiene, Kiene, Kirkwood, Kochan, Kubota, Kuchta, Li, Li, Malmstrom, Marahiel, Marc, Matsumoto, Persson, Petursdottir, Potterton, Rajashekhara, Reger, Reisch, Reisch, Sato, Schiebel, Schnicker, Seeliger, Seymour, Sievert, Simo, Souza, Sullivan, Sulzenbacher, Sun, Tapiolas, Todd, Todd, Vandecandelaere, Wang, Wang, Yoch, Zhou   +62 more
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Protein dynamics in the reductive activation of a B12-containing enzyme [PDF]

, 2017
B12-dependent proteins are involved in methyl transfer reactions ranging from the biosynthesis of methionine in humans to the formation of acetyl-CoA in anaerobic bacteria.
Goetzl, Sebastian, Teutloff, Christian, Werther, Tobias, Hennig, Sandra E., Jeoung, Jae-Hun, Bittl, Robert, Dobbek, Holger   +6 more
core   +1 more source

Analysis of polyubiquitin conjugates reveals that the Rpn10 substrate receptor contributes to the turnover of multiple proteasome targets [PDF]

, 2005
The polyubiquitin receptor Rpn10 targets ubiquitylated Sic1 to the 26S proteasome for degradation. In contrast, turnover of at least one ubiquitin-proteasome system (UPS) substrate, CPY*, is impervious to deletion of RPN10.
Deshaies, Raymond J., Graumann, Johannes, Lipford, J. Russell, Mayor, Thibault, Smith, Geoffrey T.   +4 more
core   +1 more source

From Covalent Traps to Fluorescent Beacons: The Expanding Arsenal of Chemical Probes for Studying Ubiquitin and Ubiquitin-Like Proteins. [PDF]

Angew Chem Int Ed Engl
A large variety of chemistry‐based ubiquitin probes have been developed. ABSTRACT Ubiquitin (Ub) and ubiquitin‐like proteins (Ubls) orchestrate diverse cellular processes through reversible post‐translational modification of target proteins. Their conjugation is governed by a cascade of E1 activating, E2 conjugating, and E3 ligating enzymes, while ...
Chanda S, Liu WR.
europepmc   +3 more sources