Protein dynamics in the reductive activation of a B12-containing enzyme [PDF]
B12-dependent proteins are involved in methyl transfer reactions ranging from the biosynthesis of methionine in humans to the formation of acetyl-CoA in anaerobic bacteria.
Goetzl, Sebastian +6 more
core +1 more source
The COP9 SIGNALOSOME is required for postembryonic meristem maintenance in Arabidopsis thaliana [PDF]
Cullin-RING E3 ligases (CRLs) regulate different aspects of plant development, and are activated by modification of their cullin subunit with the ubiquitin-like protein NEDD8 (NEural precursor cell expressed Developmentally Down-regulated 8) (neddylation)
Boccaccini, Alessandra +10 more
core +1 more source
Molecular characterization and analysis of the acrB gene of Aspergillus nidulans: A gene identified by genetic interaction as a component of the regulatory network that includes the CreB deubiquitination enzyme [PDF]
Copyright © 2003 by the Genetics Society of AmericaMutations in the acrB gene, which were originally selected through their resistance to acriflavine, also result in reduced growth on a range of sole carbon sources, including fructose, cellobiose ...
Adams, J. +4 more
core +1 more source
Graph theoretic methods for the analysis of structural relationships in biological macromolecules [PDF]
Subgraph isomorphism and maximum common subgraph isomorphism algorithms from graph theory provide an effective and an efficient way of identifying structural relationships between biological macromolecules.
Altschul +72 more
core +3 more sources
Identifying reference genes with stable expression from high throughput sequence data [PDF]
© The Author(s), 2012. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Frontiers in Microbiology 3 (2012): 385, doi:10.3389/fmicb.2012.00385.Genes that are constitutively ...
Alexander, Harriet +5 more
core +2 more sources
Widespread inter- and intra-domain horizontal gene transfer of d-amino acid metabolism enzymes in eukaryotes [PDF]
Analysis of the growing number of available fully-sequenced genomes has shown that Horizontal Gene Transfer (HGT) in eukaryotes is more common than previously thought.
Brock, Matthias +5 more
core +1 more source
Mechanistic insight into acrylate metabolism and detoxification in marine dimethylsulfoniopropionate-catabolizing bacteria [PDF]
Dimethylsulfoniopropionate (DMSP) cleavage, yielding dimethyl sulfide (DMS) and acrylate, provides vital carbon sources to marine bacteria, is a key component of the global sulfur cycle and effects atmospheric chemistry and potentially climate.
Adams +62 more
core +2 more sources
Characterisation of the Cullin-3 mutation that causes a severe form of familial hypertension and hyperkalaemia [PDF]
Deletion of exon 9 from Cullin‐3 (CUL3, residues 403–459: CUL3Δ403–459) causes pseudohypoaldosteronism type IIE (PHA2E), a severe form of familial hyperkalaemia and hypertension (FHHt).
Al Maskari, Raya S. +14 more
core +4 more sources
SUMOylation represses SnRK1 signaling in Arabidopsis [PDF]
The SnRK1 protein kinase balances cellular energy levels in accordance with extracellular conditions and is thereby key for plant stress tolerance. In addition, SnRK1 has been implicated in numerous growth and developmental processes from seed filling ...
Bachmair, Andreas +10 more
core +1 more source
Improved catalytic activity of ruthenium–arene complexes in the reduction of NAD+ [PDF]
A series of neutral Ru-II half-sandwich complexes of the type [(eta(6)-arene)Ru(N,N')Cl] where the arene is para-cymene (p-cym), hexamethylbenzene (hmb), biphenyl (bip), or benzene (bn) and N,N' is N-(2-aminoethyl) -4-(trifluoromethyl)benzenesulfonamide (
Abraha Habtemariam +52 more
core +2 more sources

