Results 71 to 80 of about 8,444,770 (403)

Portmanteau Goodness-of-Fit Test for Asymmetric Power GARCH Models

open access: yesAustrian Journal of Statistics, 2016
The asymptotic distribution of a vector of autocorrelations of squared residuals is derived for a wide class of asymmetric GARCH models. Portmanteau adequacy tests are deduced.
Michel Carbon, Christian Francq
doaj   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

TAP investigations of the CO2 reforming of CH4 over Pt/ZrO2 [PDF]

open access: yes, 1997
The adsorption and reaction characteristics of methane, carbon dioxide, carbon monoxide, and hydrogen have been investigated over a ZrO2support and a Pt/ZrO2catalyst by using a temporal analysis of products reactor system.
Hoebink, J.H.B.J.   +3 more
core   +3 more sources

Estimación no paramétrica de la densidad y de la regresión - previsión no paramétrica

open access: yesRevista de Matemática: Teoría y Aplicaciones, 2009
We begin with a short wiew of non parametric estimation of density and regression; then we give details and interpretation of a forecasting method, called non parametric forecasting .
Michel Carbon, Christian Francq
doaj   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Unconventional and Exotic Magnetism in Carbon-Based Structures and Related Materials [PDF]

open access: yes, 2013
The detailed analysis of the problem of possible magnetic behavior of the carbon-based structures was fulfilled to elucidate and resolve (at least partially) some unclear issues.
Kuzemsky, A. L.
core   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

open access: yesMolecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella   +18 more
wiley   +1 more source

The Carbon Reduction Transportation Initiative at Northern Arizona University [PDF]

open access: yes, 2020
: The Carbon Reduction Transportation Initiative (CRTI) at Northern Arizona University (NAU) was created to improve both recruitment and retention efforts while significantly lowering NAU’s carbon footprint. Through a collective subsidization between NAU

core  

Differential contractile response of critically ill patients to neuromuscular electrical stimulation [PDF]

open access: yes, 2019
BACKGROUND: Neuromuscular electrical stimulation (NMES) has been investigated as a preventative measure for intensive care unit-acquired weakness. Trial results remain contradictory and therefore inconclusive.
Carbon, Niklas M.   +5 more
core   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy