Results 81 to 90 of about 5,307,624 (304)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Carbon Anode in Carbon History [PDF]

open access: yesMolecules, 2020
This study examines how the several major industries, associated with a carbon artifact production, essentially belong to one, closely knit family. The common parents are the geological fossils called petroleum and coal. The study also reviews the major developments in carbon nanotechnology and electrocatalysis over the last 30 years or so.
openaire   +3 more sources

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Guiding incumbent companies in navigating digital transformations: A qualitative study on structural ambidexterity and strategic leadership [PDF]

open access: yesJournal of Entrepreneurship, Management and Innovation
PURPOSE: Despite digital transformation being a focus topic for incumbent companies, organizational structures are a significant barrier to their success.
Sabrina Hoessler, Claus-Christian Carbon
doaj   +1 more source

Computing and estimating information matrices of weak arma models [PDF]

open access: yes
Numerous time series admit "weak" autoregressive-moving average (ARMA) representations, in which the errors are uncorrelated but not necessarily independent nor martingale differences.
Boubacar Mainassara, Yacouba   +2 more
core   +1 more source

Carbon mineralization and microbial activity in agricultural topsoil and subsoil as regulated by root nitrogen and recalcitrant carbon concentrations [PDF]

open access: yes, 2018
Aims Mechanisms of subsoil carbon sequestration from deep-rooted plants are elusive, but may contribute to climate change mitigation. This study addressed the role of root chemistry on carbon mineralization and microbiology in a temperate agricultural ...
Elsgaard, Lars   +4 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Cutting carbon, not the economy [PDF]

open access: yes
A drastic change in the way we produce and consume energy is necessary to contain the risk of global environmental catastrophe. For its part, the EU has set agreed to a greenhouse gas reduction target of 80-95 percent by 2050, compared to 1990. However,
Georg Zachmann
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Carbon nanotube chirality determines properties of encapsulated linear carbon chain

open access: yes, 2018
Long linear carbon chains encapsulated inside carbon nanotubes are a very close realization of carbyne, the truly one-dimensional allotrope of carbon. Here we study individual pairs of double-walled carbon nanotubes and encapsulated linear carbon chains ...
Heeg, Sebastian   +4 more
core   +2 more sources

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