Results 71 to 80 of about 3,444,934 (310)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

A1045_East_Carbon_High_School_0030_HD_18_fps

open access: yes, 1974
Film showing the East Carbon High School football team playing at home against South Summit High (from Kamas). East Carbon players are in the light blue uniforms with red helmets. Midway through the game, it begins to snow. East Carbon loses 6-42 and the
East Carbon High School
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Guide to Communicating Carbon Pricing

open access: yes, 2018
Stakeholder and public support are critical for an enduring and robust carbon pricing policy. How jurisdictions communicate their carbon pricing policy plays a key role in creating and maintaining that support.
Partnership for Market Readiness   +1 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

A1045_East_Carbon_High_School_0048_HD_18_fps

open access: yes, 1958
Film showing the East Carbon High School football team playing against an unidentified team. East Carbon wears the red helmets.
East Carbon High School
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New Nanostructured Carbon Coating Inhibits Bacterial Growth, but Does Not Influence on Animal Cells [PDF]

open access: yes, 2020
An electrospark technology has been developed for obtaining a colloidal solution containing nanosized amorphous carbon. The advantages of the technology are its low cost and high performance.
Misakyan, Mamikon A.   +41 more
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

A1045_East_Carbon_High_School_0036_HD_18_fps

open access: yes, 1980
Film showing the East Carbon High School football team playing against Park City at East Carbon on Sept. 12, 1980. There are shots of the scoreboard, but they are too washed out to see who won.
East Carbon High School
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Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

A1045_East_Carbon_High_School_0022_edit

open access: yes, 1960
Film showing the East Carbon High School Basketball team playing against San Juan (Blanding), year unknown.
East Carbon High School
core  

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