Results 81 to 90 of about 8,444,770 (403)

An approach for coherent periodogram averaging of tilt‐series data for improved contrast transfer function estimation

open access: yesFEBS Open Bio, EarlyView.
The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

open access: yesFEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa   +13 more
wiley   +1 more source

Extending the Implicit Association Test (IAT): assessing consumer attitudes based on multi-dimensional implicit associations. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: The authors present a procedural extension of the popular Implicit Association Test (IAT) that allows for indirect measurement of attitudes on multiple dimensions (e.g., safe-unsafe; young-old; innovative-conventional, etc.) rather than on a ...
Valentin Gattol   +2 more
doaj   +1 more source

Carbonic Acid and Bisulphide of Carbon [PDF]

open access: yesScientific American, 1883
n ...
openaire   +2 more sources

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

open access: yesFEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

On Carbon Burning in Super Asymptotic Giant Branch Stars [PDF]

open access: yes, 2015
We explore the detailed and broad properties of carbon burning in Super Asymptotic Giant Branch (SAGB) stars with 2755 MESA stellar evolution models.
Farmer, R., Fields, C. E., Timmes, F. X.
core   +2 more sources

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

open access: yesFEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Portmanteau goodness-of-fit test for asymmetric power GARCH models [PDF]

open access: yes
The asymptotic distribution of a vector of autocorrelations of squared residuals is derived for a wide class of asymmetric GARCH models. Portmanteau adequacy tests are deduced.
Carbon, Michel, Francq, Christian
core   +1 more source

One-carbon metabolism in cancer [PDF]

open access: yes, 2017
Cells require one-carbon units for nucleotide synthesis, methylation and reductive metabolism, and these pathways support the high proliferative rate of cancer cells.
AJ MacFarlane   +55 more
core   +1 more source

A New Metrical Funerary Curse from Miletoupolis

open access: yesGephyra
An inscribed funerary stele probably from Miletoupolis has been recently published by E. Laflı and M.E. Uyar (Laflı – Uyar 2021, 77-79 no. 2).
Jan-mathieu Carbon
doaj   +1 more source

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