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The history of ion beam therapy in Germany

open access: yesZeitschrift für Medizinische Physik, 2022
The advantageous depth dose profile of ion beams together with state of the art beam delivery and treatment planning systems allow for highly conformal tumor treatments in patients.
Oliver Jäkel   +2 more
doaj   +3 more sources

Feasibility of ultra-low-field MRI in an ion beam treatment room for online MR-guided particle therapy [PDF]

open access: yesPhysics and Imaging in Radiation Oncology
Background and purpose:: Online MR-guided particle therapy may improve beam delivery precision and treatment efficacy. Ultra-low-field (ULF) MRI may enable image guidance with minimal modification of existing facilities.
Julia Pfitzer   +4 more
doaj   +2 more sources

The GATE-RTion/IDEAL Independent Dose Calculation System for Light Ion Beam Therapy

open access: yesFrontiers in Physics, 2021
Patient specific quality assurance can be improved using an independent dose calculation system. In addition, the implementation of such a system may support light ion beam therapy facilities in reducing the needs for beam time, by substituting some of ...
L. Grevillot   +11 more
doaj   +1 more source

Study of an Online Plan Verification Method and the Sensitivity of Plan Delivery Accuracy to Different Beam Parameter Errors in Proton and Carbon Ion Radiotherapy

open access: yesFrontiers in Oncology, 2021
For scanning beam particle therapy, the plan delivery accuracy is affected by spot size deviation, position deviation and particle number deviation.
Jun Zhao   +7 more
doaj   +1 more source

Particle radiation therapy in the management of adult high-grade glioma: A narrative review

open access: yesGlioma, 2020
This narrative review summarizes the current status of the use of particle radiation therapy on the treatment of adult malignant gliomas. Due to the unique physical property, particle (e.g., proton or carbon-ion) beam radiation therapy can improve ...
Lin Kong, Jiade J Lu
doaj   +1 more source

Particle beam therapy for nasopharyngeal cancer: A systematic review and meta-analysis

open access: yesClinical and Translational Radiation Oncology, 2022
Background/purpose: A systematic review and meta-analysis were performed to better understand the benefits of particle beam therapy for nasopharyngeal cancer (NPC) treatment.
Wai Tong Ng   +6 more
doaj   +1 more source

Possibilities and challenges when using synthetic computed tomography in an adaptive carbon-ion treatment workflow

open access: yesZeitschrift für Medizinische Physik, 2023
Background and purpose: Anatomical surveillance during ion-beam therapy is the basis for an effective tumor treatment and optimal organ at risk (OAR) sparing. Synthetic computed tomography (sCT) based on magnetic resonance imaging (MRI) can replace the X-
Barbara Knäusl   +6 more
doaj   +1 more source

Carbon Ion Therapy Inhibits Esophageal Squamous Cell Carcinoma Metastasis by Upregulating STAT3 Through the JAK2/STAT3 Signaling Pathway

open access: yesFrontiers in Public Health, 2020
Radiation therapy is an important component of the comprehensive treatment of esophageal cancer. However, conventional radiation resistance is one of the main reasons for treatment failure.
Hongtao Luo   +16 more
doaj   +1 more source

In vitro evaluation of photon and carbon ion radiotherapy in combination with cisplatin in head and neck squamous cell carcinoma cell lines

open access: yesFrontiers in Oncology, 2023
BackgroundHeavy ion radiotherapy, such as carbon ion radiotherapy (CIRT), has multiple advantages over conventional photon therapy. Cisplatin, as a classic anti-tumor drugs, has been tested and discovered as a photon radiosensitizer in several cell lines,
Xumeng Fang   +17 more
doaj   +1 more source

The influence of beam delivery uncertainty on dose uniformity and penumbra for pencil beam scanning in carbon-ion radiotherapy.

open access: yesPLoS ONE, 2021
The dose uniformity and penumbra in the treatment field are important factors in radiotherapy, which affects the outcomes of radiotherapy. In this study, the integrated depth-dose-distributions (IDDDs) of 190 MeV/u and 260 MeV/u carbon beams in the ...
Yue Li   +6 more
doaj   +1 more source

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