Results 21 to 30 of about 9,814 (114)

Multiscale modeling for cancer radiotherapies

Cancer Nanotechnology, 2019
Background Ion-beam cancer therapy, an alternative to a common radiation therapy with X-rays, has been used clinically around the world since 1990s; the number of proton therapy centers as well as facilities using heavier ions such as α-particles and ...
Eugene Surdutovich, Andrey V. Solov’yov   +1 more
doaj   +1 more source

Comparison of intensity modulated radiotherapy (IMRT) with intensity modulated particle therapy (IMPT) using fixed beams or an ion gantry for the treatment of patients with skull base meningiomas

Radiation Oncology, 2012
Background To examine the potential improvement in treatment planning for patients with skull base meningioma using IMRT compared to carbon ion or proton beams with and without a gantry.
Kosaki Katsura, Ecker Swantje, Habermehl Daniel, Rieken Stefan, Jäkel Oliver, Herfarth Klaus, Debus Jürgen, Combs Stephanie E   +7 more
doaj   +1 more source

Charged particle therapy for high-grade gliomas in adults: a systematic review

Radiation Oncology, 2023
High-grade gliomas are the most common intracranial malignancies, and their current prognosis remains poor despite standard aggressive therapy. Charged particle beams have unique physical and biological properties, especially high relative biological ...
Yuhang Wang, Ruifeng Liu, Qiuning Zhang, Meng Dong, Dandan Wang, Junru Chen, Yuhong Ou, Hongtao Luo, Kehu Yang, Xiaohu Wang   +9 more
doaj   +1 more source

Impact of Various Beam Parameters on Lateral Scattering in Proton and Carbon-ion Therapy

Journal of Biomedical Physics and Engineering, 2015
Background: In radiation therapy with ion beams, lateral distributions of absorbed dose in the tissue are important. Heavy ion therapy, such as carbon-ion therapy, is a novel technique of high-precision external radiotherapy which has advantages over ...
Ebrahimi Loushab M., Mowlavi A. A., Hadizadeh M. H., Izadi R., Jia S. B.   +4 more
doaj  

Simulation Analysis and Radiation Protection Study of Induced Radioactivity in Carbon Ion Therapy Systems

Zhongguo yiliao qixie zazhi
Objective Addressing the issue of induced radioactivity in carbon ion therapy system operation, to systematically evaluate the impact of beam parameters on the distribution of induced radiation field in carbon ion therapy room and develop radiation ...
Siyang LIU, Chunying JIAO, Shibing XIE, Guotao FU, Peichen WANG, Yulin DENG   +5 more
doaj   +1 more source

Experience and new prospects of PET imaging for ion beam therapy monitoring

Zeitschrift für Medizinische Physik, 2023
Pioneering investigations on the usage of positron-emission-tomography (PET) for the monitoring of ion beam therapy with light (protons, helium) and heavier (stable and radioactive neon, carbon and oxygen) ions started shortly after the first realization
Katia Parodi, Taiga Yamaya, Pawel Moskal
doaj   +1 more source

Double multiturn injection scheme for generating mixed helium and carbon ion beams at medical synchrotron facilities

Physical Review Accelerators and Beams
The low relative charge-to-mass ratio offset of 0.065% between fully ionized helium-4 and carbon-12 ions enables simultaneous acceleration in hadron therapy synchrotrons.
Matthias Kausel, Claus Schmitzer, Andreas Gsponer, Markus Wolf, Hermann Fuchs, Felix Ulrich-Pur, Thomas Bergauer, Albert Hirtl, Nadia Gambino, Elisabeth Renner   +9 more
doaj   +1 more source

Characterization of the mixed radiation field produced by carbon and oxygen ion beams of therapeutic energy: A Monte Carlo simulation study

Journal of Medical Physics, 2019
Purpose: The main advantages of charged particle radiotherapy compared to conventional X-ray external beam radiotherapy are a better tumor conformality coupled with the capability of treating deep-seated radio-resistant tumors. This work investigates the
C K Ying, David Bolst, Anatoly Rosenfeld, Susanna Guatelli   +3 more
doaj   +1 more source

Simulation study for the energy and position reconstruction performances of the beam monitoring system of Carbon Ion Radiation Therapy using GEANT4.

PLoS ONE
Carbon Ion Radiation Therapy is operated in several countries because of its advantage to have high dose concentration and/or high linear energy transfer (LET). To estimate the beam performance of Carbon Ion Radiation Therapy, we target the 1% energy and
Yun Eo, Na Hye Kwon, Joonsuk Bae, Byunggu Cheon, Guk Cho, Suyong Choi, Hyunsuk Do, Seungkyu Ha, Changgi Huh, Kyuyeong Hwang, Haeun Jang, Seoyun Jang, Yoonjun Jang, Jinryong Jeong, Beomkyu Kim, Bobae Kim, Dongwoon Kim, Sungwon Kim, Sanghyun Ko, Hyupwoo Lee, Hyungjun Lee, Jason Lee, Junghyun Lee, Sehwook Lee, Woochan Lee, Yunjae Lee, Sanghoon Lim, Hyesung Park, Jaehyeok Ryu, Jin Sung Kim, Min Sang Ryu, Hwidong Yoo, Dong Wook Kim, Minsuk Kim   +33 more
doaj   +1 more source

Feasibility study of 4D-online monitoring of density gradients induced by lung cancer treatment using carbon ions

Frontiers in Oncology
Tumor motion is a major challenge for scanned ion-beam therapy. In the case of lung tumors, strong under- and overdosage can be induced due to the high density gradients between the tumor- and bone tissues compared to lung tissues.
Claire-Anne Reidel, Enrico Pierobon, Felix Horst, Lévana Gesson, Lévana Gesson, Athena Paz, Christian Graeff, Christian Graeff, Timo Steinsberger, Klemens Zink, Klemens Zink, Matthias Witt, Matthias Witt, Yannick Senger, Christian Finck, Marie Vanstalle, Chiara La Tessa, Chiara La Tessa, Marco Durante, Marco Durante, Marco Durante, Uli Weber, Uli Weber, Christoph Schuy   +23 more
doaj   +1 more source