Results 11 to 20 of about 21,417 (198)

Development of Clinical Programs for Carbon Ion Beam Therapy at MedAustron.

International Journal of Particle Therapy, 2015
As the first particle therapy center in Austria, MedAustron is currently set up for operation with an expected start of clinical operation in 2016. MedAustron is designed as a dualparticle facility using proton and carbon ion beams for clinical and ...
M. Stock, P. Georg, R. Mayer, T. Böhlen, S. Vatnitsky   +4 more
semanticscholar   +3 more sources

Comparison of the radiobiological effect of carbon ion beam therapy and conventional radiation therapy on cervical cancer. [PDF]

Journal of Radiation Research, 2008
Little clinical evidence has been provided to show the minimization of radiation resistance of tumors using high linear energy transfer radiation. We therefore investigated the radiobiological and molecular pathological aspects of carbon beam therapy.
Yoshiyuki Suzuki, T. Nakano, T. Ohno, K. Oka   +3 more
semanticscholar   +3 more sources

Design of a compact gantry for carbon-ion beam therapy [PDF]

Physical Review Accelerators and Beams, 2019
This paper presents the design of a compact gantry that uses superconducting bending magnets (BMs), for use in carbon-ion beam therapy. The size of the gantry is comparable to those of existing gantries that are used for proton-beam therapy. The designed gantry provides point-to-parallel scanning over an area of 20  cm×20  cm at the isocenter, and has ...
Jaehyun Kim, M. Yoon
semanticscholar   +4 more sources

Carbon ions beam therapy monitoring with the INSIDE in-beam PET [PDF]

Physics in Medicine & Biology, 2018
Abstract In vivo range monitoring techniques are necessary in order to fully take advantage of the high dose gradients deliverable in hadrontherapy treatments. Positron emission tomography (PET) scanners can be used to monitor beam-induced activation in tissues and hence measure the range.
Pennazio, Francesco, Battistoni, Giuseppe, Bisogni, Maria Giuseppina, Camarlinghi, Niccolò, Ferrari, Alfredo, Ferrero, Veronica, Fiorina, Elisa, Morrocchi, Matteo, Sala, Paola, Sportelli, Giancarlo, Wheadon, Richard, Cerello, Piergiorgio   +11 more
openaire   +3 more sources

Potential benefits of using radioactive ion beams for range margin reduction in carbon ion therapy [PDF]

Scientific Reports, 2022
AbstractSharp dose gradients and high biological effectiveness make ions such as 12C an ideal tool to treat deep-seated tumors, however, at the same time, sensitive to errors in the range prediction. Tumor safety margins mitigate these uncertainties, but during the irradiation they lead to unavoidable damage to the surrounding healthy tissue.
Sokol, Olga, Cella, Laura, Boscolo, Daria, Horst, Felix, Oliviero, Caterina, Pacelli, Roberto, Palma, Giuseppe, De Simoni, Micol, Conson, Manuel, Caroprese, Mara, Weber, Ulrich, Graeff, Christian, Parodi, Katia, Durante, Marco   +13 more
openaire   +6 more sources

Dose quantification in carbon ion therapy using in-beam positron emission tomography [PDF]

Physics in Medicine & Biology, 2020
Abstract This work presents an iterative method for the estimation of the absolute dose distribution in patients undergoing carbon ion therapy, via analysis of the distribution of positron annihilations resulting from the decay of positron-emitting fragments created in the target volume. The proposed method relies
Harley Rutherford, Andrew Chacon, Akram Mohammadi, Sodai Takyu, Hideaki Tashima, Eiji Yoshida, Fumihiko Nishikido, Theresa Hofmann, Marco Pinto, Daniel R Franklin, Taiga Yamaya, Katia Parodi, Anatoly B Rosenfeld, Susanna Guatelli, Mitra Safavi-Naeini   +14 more
openaire   +2 more sources

Experience and new prospects of PET imaging for ion beam therapy monitoring.

Zeitschrift für Medizinische Physik, 2022
Pioneering investigations on the usage of positron-emission-tomography (PET) for the monitoring of ion beam therapy with light (protons, helium) and heavier (stable and radioactive neon, carbon and oxygen) ions started shortly after the first realization
Katia Parodi, T. Yamaya, P. Moskal
semanticscholar   +1 more source

High–Linear Energy Transfer Irradiation in Clinical Carbon-Ion Beam With the Linear Energy Transfer Painting Technique for Patients With Head and Neck Cancer

Advances in Radiation Oncology, 2023
Purpose Dose-averaged linear energy transfer (LETd) is one of the important factors in determining clinical outcomes for carbon-ion radiation therapy. Innovative LET painting (LP) has been developed as an advanced form of conventional intensity modulated
R. Kohno, M. Koto, H. Ikawa, Sung Hyun Lee, Kana Sato, Mitsuyasu Hashimoto, T. Inaniwa, T. Shirai   +7 more
semanticscholar   +1 more source

Development and validation of MonteRay, a fast Monte Carlo dose engine for carbon ion beam radiotherapy.

Medical Physics (Lancaster), 2023
BACKGROUND Monte Carlo (MC) simulations are considered the gold-standard for accuracy in radiotherapy dose calculation; so far however, no commercial treatment planning system (TPS) provides a fast MC for supporting clinical practice in carbon ion ...
Peter Lysakovski, B. Kopp, T. Tessonnier, S. Mein, A. Ferrari, T. Haberer, J. Debus, A. Mairani   +7 more
semanticscholar   +1 more source

Dosimetric validation of a GPU-based dose engine for a fast in-silico patient-specific quality assurance program in light ion beam therapy.

Medical Physics (Lancaster), 2022
BACKGROUND With rapid evolutions of fast and sophisticated calculation techniques and delivery technologies, clinics are almost facing a daily patient-specific (PS) plan adaptation, which would make a conventional experimental quality assurance (QA ...
G. Magro, M. Fassi, A. Mirandola, E. Rossi, S. Molinelli, S. Russo, A. Bazani, A. Vai, M. Ciocca, M. Donetti, A. Mairani   +10 more
semanticscholar   +1 more source