Results 61 to 70 of about 21,417 (198)

Advanced Dental Composite Technology via Bisilanized Dual‐Action Nanofillers for Biofilm Control

Advanced Science, EarlyView.
A multimodal research strategy has led to the development of an innovative resin‐based composite (RBC) with dual antibacterial action. The S_CM‐RBC formula showed strong antibiofilm activity, excellent mechanical strength, and biosafety. It effectively controlled oral bacteria in prevention of caries recurrence, and maintained pulp health in a rat ...
Chenmin Yao, Line Etiennot, Naiera Zayed, Shengjie Liang, Mehraveh Saghi, Jelle Verdonck, Lingyue Liu, Fei Zhang, Wim Teughels, Cui Huang, Kirsten Van Landuyt, Bart Van Meerbeek   +11 more
wiley   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

A Brain‐Penetrant Nanobody Reveals GSK3β‐Driven Proline‐Directed Phosphorylation as a Master Regulator of Ischemic Neurodegeneration

Advanced Science, EarlyView.
A brain‐targeted nanoparticle enables delivery of a therapeutic nanobody (Nb.29E9) that inhibits pathogenic GSK3β signaling. This intervention restores AMPK/mTORC1/TGFβ homeostasis, attenuates neuroinflammation and oxidative stress, and promotes long‐term functional recovery after ischemic stroke.
Lan Li, Muyang Li, Lei Sun, Ying Yang, Yuanshun Wu, Ziyi Yin, Anni Wang, Peiyang Zhou, Shaoxiang Luo, Jian Chen, Jun Qin, Zhibing Ai, Zilong Yuan, Zhiqiang Dong, Min Zhang   +14 more
wiley   +1 more source

Thin segmented silicon detectors for single ion tracking in carbon ion beam therapy: Performance insights

Physica Medica
Carbon ion radiotherapy (CIRT) leverages the unique physical and radiobiological properties of carbon ions to achieve superior dose distribution and enhanced biological effectiveness, making it an effective treatment for challenging tumors while maximizing the sparing of healthy tissues.
Montalvan Olivares, D. M., Mas Milian, F., Marti Villarreal, O. A., Medina, E., Abujami, M., Vignali, M. Centis, Cirio, R., Data, E., Deut, U., Donetti, M., Mazinani, M. Fadavi, Ferrero, V., Ferro, A., Fiorina, E., Mostardi, F., Paternoster, G., Pennazio, F., Pullia, M., Ranjbar, S., Sacchi, R., Sola, V., Vignati, A., Giordanengo, S.   +22 more
openaire   +3 more sources

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

All‐Flex Plasma Patch for In Vivo Delivery of Reactive Species

Advanced Science, EarlyView.
A fully flexible plasma patch enables stable, conformal treatment on complex biological surfaces and enhances transdermal delivery of reactive species. This platform achieves significant tumor suppression in vivo and reveals coordinated regulation of calcium signaling, metabolism, and programmed cell death, providing a promising strategy for safe and ...
Luxiang Zhao, Abulaihaiti Tuergong, Hanshu Yang, Shuang Xue, An Yan, Mingzhen Wang, Weilong Song, Wenzhe Si, Ruixue Wang   +8 more
wiley   +1 more source

Impact of Various Beam Parameters on Lateral Scattering in Proton and Carbon-ion Therapy.

Journal of biomedical physics & engineering, 2015
In radiation therapy with ion beams, lateral distributions of absorbed dose in the tissue are important. Heavy ion therapy, such as carbon-ion therapy, is a novel technique of high-precision external radiotherapy which has advantages over proton therapy in terms of dose locality and biological effectiveness.In this study, we used Monte Carlo method ...
Ebrahimi Loushab M., Mowlavi A. A., Hadizadeh M. H., Izadi R., Jia S. B.   +4 more
openaire   +2 more sources

From Materials to Medical Images: Translating Perovskite‐Based X‐Ray Detectors Toward Clinical Imaging

Advanced Science, EarlyView.
This review examines perovskite‐based X‐ray detectors from a materials‐to‐medical‐images perspective. Recent progress in perovskite‐based X‐ray detectors is discussed with emphasis on their relevance to clinical imaging. The key barriers to clinical implementation are analyzed.
Sibin Wang, Yongrui Yang, Kun Zhang, Xiaojuan Lu, Hong Yin, Yali Qiao, Xiaojia Zheng, Xiao Zhang, Yanlin Song   +8 more
wiley   +1 more source

Illuminating the Intracellular World: Breakthroughs in Nanoscale Optoelectronics

Advanced Electronic Materials, EarlyView.
This perspective explores optoelectronic biointerfaces spanning macroscale flexible devices to nanoscale intracellular systems, emphasizing their integration across dimensions. It examines capacitive, Faradaic, and photothermal mechanisms that enable light‐driven control of cellular activity and highlights key material and design challenges in ...
Tania Assaf, Menahem Y. Rotenberg
wiley   +1 more source

Robot‐Assisted Measurement of the Critical Micelle Concentration

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
The study introduces (SIMO) smart integrator for manual operations, a robotic platform for precise, repeatable determination of (CMC) critical micelle concentration in surfactants. SIMO reduces standard deviation by 80% compared to manual methods. Surfactant, dye, and diluent selection, robotic protocols, and data handling are detailed.
Vincenzo Scamarcio, Gadi Slor, Josie Hughes, Francesco Stellacci   +3 more
wiley   +1 more source