Carbon Ion Therapy: A Modern Review of an Emerging Technology [PDF]
Frontiers in Oncology, 2020 Radiation therapy is one of the most widely used therapies for malignancies. The therapeutic use of heavy ions, such as carbon, has gained significant interest due to advantageous physical and radiobiologic properties compared to photon based therapy. By
Timothy D. Malouff +5 more
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Technical Note: Improving the workflow in a carbon ion therapy center with custom software for enhanced patient care [PDF]
Technical Innovations & Patient Support in Radiation OncologyCarbon-ion radiation therapy (CIRT) is an up-and-coming modality for cancer treatment. Implementation of CIRT requires collaboration among specialists like radiation oncologists, medical physicists, and other healthcare professionals.
Sridhar Yaddanapudi +5 more
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Dosimetric impact of stopping power for human bone porosity with dual-energy computed tomography in scanned carbon-ion therapy treatment planning [PDF]
Scientific ReportsFew reports have documented how the accuracy of stopping power ratio (SPR) prediction for porous bone tissue affects the dose distribution of scanned carbon-ion beam therapy.
Masashi Yagi +11 more
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Carbon Ion Therapy Inhibits Esophageal Squamous Cell Carcinoma Metastasis by Upregulating STAT3 Through the JAK2/STAT3 Signaling Pathway [PDF]
Frontiers in Public Health, 2020 Radiation therapy is an important component of the comprehensive treatment of esophageal cancer. However, conventional radiation resistance is one of the main reasons for treatment failure.
Hongtao Luo +16 more
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The preliminary results of proton and carbon ion therapy for chordoma and chondrosarcoma of the skull base and cervical spine [PDF]
Radiation Oncology, 2019 Purpose To evaluate the short-term outcomes in terms of tumor control and toxicity of patients with skull base or cervical spine chordoma and chondrosarcoma treated with intensity-modulated proton or carbon-ion radiation therapy.
Xiyin Guan +8 more
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Bimodal intensity-modulated radiotherapy in combination with carbon ion therapy (C12) of mucosal melanomas - data of the last decade from Heidelberg University Hospital [PDF]
Frontiers in OncologyIntroductionDue to the rarity of mucosal melanomas, few recent studies can be found investigating the success and side effects of therapy for this entity with large numbers of patients.
Lukas Bauer +44 more
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Unsupervised Deep Learning for Synthetic CT Generation from CBCT Images for Proton and Carbon Ion Therapy for Paediatric Patients [PDF]
SensorsImage-guided treatment adaptation is a game changer in oncological particle therapy (PT), especially for younger patients. The purpose of this study is to present a cycle generative adversarial network (CycleGAN)-based method for synthetic computed ...
Matteo Pepa +10 more
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Flourish of Proton and Carbon Ion Radiotherapy in China
Frontiers in Oncology, 2022 Proton and heavy ion therapy offer superior relative biological effectiveness (RBE) in the treatment of deep-seated tumors compared with conventional photon radiotherapy due to its Bragg-peak feature of energy deposition in organs. Many proton and carbon
Yue Li +8 more
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Carbon ion radiotherapy for recurrent ameloblastoma: A case report
SAGE Open Medical Case Reports, 2022 Ameloblastoma is a kind of benign, odontogenic tumor of epithelial origin, and surgery is mainstay treatment method; however, recurrence is common, and usually the treatment for recurrence is still surgery.
Yihe Zhang +9 more
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BMC Cancer, 2022 Background Some cancers such as sarcomas (bone and soft tissue sarcomas) and adenoid cystic carcinomas are considered as radioresistant to low linear energy transfer radiation (including photons and protons) and may therefore beneficiate from a carbon ...
Jacques Balosso +22 more
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