Results 31 to 40 of about 5,822,485 (294)

The history of ion beam therapy in Germany

Zeitschrift für Medizinische Physik, 2022
The advantageous depth dose profile of ion beams together with state of the art beam delivery and treatment planning systems allow for highly conformal tumor treatments in patients.
Oliver Jäkel, Gerhard Kraft, Christian P. Karger   +2 more
doaj   +1 more source

A Review of Particle Therapy for Skull Base Tumors: Modern Considerations and Future Directions [PDF]

International Journal of Particle Therapy, 2021
Skull base tumors constitute one of the established indications for particle therapy, specifically proton therapy. However, a number of prognostic factors, practical clinical management issues, and the emerging role of carbon ion therapy remain subjects ...
Eugen B. Hug, MD, Maciej Pelak, MD, PhD, Steven J. Frank, MD, Piero Fossati, PhD   +3 more
doaj   +1 more source

Effect of carbon ion implantation on the tribology of metal-on-metal bearings for artificial joints [PDF]

, 2017
Metal-on-metal (MoM) bearings have become popular due to a major advantage over metal-on-polymer bearings for total hip arthroplasty in that the larger femoral head and hydrodynamic lubrication of the former reduce the rate of wear.
Yonekura A, Higuchi, Takashi, Tomita M, Yonekura, Akihiko, Sunagawa S, Baba K, Higuchi T, Koseki, Hironobu, Takashi Higuchi, Osaki, Makoto, Makoto Osaki, Sunagawa, Sinya, Sinya Sunagawa, Koseki H, Hironobu Koseki, Osaki M, Baba, Koumei, Masato Tomita, Tomita, Masato, Koumei Baba, Akihiko Yonekura   +20 more
core   +1 more source

Ion-Type Dependence of DNA Electronic Excitation in Water under Proton, α‑Particle, and Carbon Ion Irradiation: A First-Principles Simulation Study

, 2023
Understanding how the electronic excitation of DNA changes in response to different high-energy particles is central to advancing ion beam cancer therapy and other related approaches, such as boron neutron capture therapy.
Christopher Shepard (17363305), Yosuke Kanai (1285974)   +1 more
core   +1 more source

RBE and related modeling in carbon-ion therapy

Physics in Medicine & Biology, 2017
Carbon ion therapy is a promising evolving modality in radiotherapy to treat tumors that are radioresistant against photon treatments. As carbon ions are more effective in normal and tumor tissue, the relative biological effectiveness (RBE) has to be calculated by bio-mathematical models and has to be considered in the dose prescription. This review (i)
Christian P, Karger, Peter, Peschke
openaire   +2 more sources

Does particle radiation have superior radiobiological advantages for prostate cancer cells? A systematic review of in vitro studies

European Journal of Medical Research, 2022
Background Charged particle beams from protons to carbon ions provide many significant physical benefits in radiation therapy. However, preclinical studies of charged particle therapy for prostate cancer are extremely limited.
Tian-Qi Du, Ruifeng Liu, Qiuning Zhang, Hongtao Luo, Yanliang Chen, Mingyu Tan, Qian Wang, Xun Wu, Zhiqiang Liu, Shilong Sun, Kehu Yang, Jinhui Tian, Xiaohu Wang   +12 more
doaj   +1 more source

Electron string ion sources for carbon ion cancer therapy accelerators [PDF]

Review of Scientific Instruments, 2015
The type of the Electron String Ion Sources (ESIS) is considered to be the appropriate one to produce pulsed C4+ and C6+ ion beams for cancer therapy accelerators. In fact, the new test ESIS Krion-6T already now provides more than 1010 C4+ ions per pulse and about 5 × 109 C6+ ions per pulse.
A. Yu. Boytsov, D. E. Donets, E. D. Donets, E. E. Donets, K. Katagiri, K. Noda, D. O. Ponkin, A. Yu. Ramzdorf, V. V. Salnikov, V. B. Shutov   +9 more
openaire   +3 more sources

Particle Beam Radiation Therapy for Skull Base Sarcomas

Frontiers in Oncology, 2020
Background: To report the clinical experience of carbon-ion and proton radiation therapy for skull base sarcomas.Methods: An analysis of the retrospective data registry from the Shanghai Proton and Heavy Ion Center for patients with skull base sarcomas ...
Jing Yang, Jing Yang, Weixu Hu, Weixu Hu, Xiyin Guan, Xiyin Guan, Jiyi Hu, Jiyi Hu, Jing Gao, Jing Gao, Xianxin Qiu, Xianxin Qiu, Qingting Huang, Qingting Huang, Wenna Zhang, Wenna Zhang, Lin Kong, Lin Kong, Lin Kong, Jiade J. Lu, Jiade J. Lu   +20 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

A Feasibility Study of In-Beam PET Imaging for Dose Verification in Carbon Therapy Using Free PET

Journal of Isotopes, 2022
In-beam PET imaging provides a noninvasive method to monitor the dose distribution in real-time for particle therapy such as carbon ion therapy and proton therapy.
PEI Changxu;WEN Jing;LIU Meilou;GUO Dian;ZHANG Qinghua;HUANG Chuan;LI Yingguo;YIN Yongzhi;CHEN Ximeng
doaj