Irradiation-Induced Changes in the Immunogenicity of Lung Cancer Cell Lines: Based on Comparison of X-rays and Carbon Ions [PDF]
Frontiers in Public Health, 2021 Increasing the immunogenicity of tumors is considered to be an effective means to improve the synergistic immune effect of radiotherapy. Carbon ions have become ideal radiation for combined immunotherapy due to their particular radiobiological advantages.
Juntao Ran +7 more
doaj +3 more sources
Discriminative detection of laser-accelerated multi-MeV carbon ions utilizing solid state nuclear track detectors [PDF]
Scientific Reports, 2021 A new diagnosis method for the discriminative detection of laser-accelerated multi-MeV carbon ions from background oxygen ions utilizing solid-state nuclear track detectors (SSNTDs) is proposed. The idea is to combine two kinds of SSNTDs having different
Takamasa Hihara +10 more
doaj +3 more sources
Role of Oxidative Stress Signaling, Nrf2, on Survival and Stemness of Human Adipose-Derived Stem Cells Exposed to X-rays, Protons and Carbon Ions [PDF]
AntioxidantsSome cancers have a poor prognosis and often lead to local recurrence because they are resistant to available treatments, e.g., glioblastoma. Attempts have been made to increase the sensitivity of resistant tumors by targeting pathways involved in the ...
Mira Hammad +4 more
doaj +2 more sources
Carbon Ions for Hypoxic Tumors: Are We Making the Most of Them? [PDF]
Cancers (Basel), 2023 Simple Summary Carbon-ion radiotherapy is a potential elective treatment option for hypoxic tumors. Its high linear energy transfer enables enhanced cell killing in radiation-resistant tumors, while the Bragg peak ensures precise targeting.
Sokol O, Durante M.
europepmc +2 more sources
Dose calculation accuracy in particle therapy: Comparing carbon ions with protons. [PDF]
Med Phys, 2021 Purpose This work presents the validation of an analytical pencil beam dose calculation algorithm in a commercial treatment planning system (TPS) for carbon ions by measurements of dose distributions in heterogeneous phantom geometries.
Ruangchan S +4 more
europepmc +2 more sources
Does FLASH deplete Oxygen? Experimental Evaluation for Photons, Protons and Carbon Ions. [PDF]
Medical Physics (Lancaster), 2021 PURPOSE To investigate experimentally, if FLASH irradiation depletes oxygen within water for different radiation types such as photons, protons and carbon ions.
J. Jansen +8 more
semanticscholar +1 more source
Efficacy and feasibility of re-irradiation using carbon ions for pancreatic cancer that recurs after carbon-ion radiotherapy. [PDF]
Clin Transl Radiat Oncol, 2021 Highlights • Carbon-ion re-irradiation for pancreatic cancer; feasibility and efficacy.• Adjuvant chemotherapy improve local control of re-irradiation using carbon ions.• Carbon-ion radiotherapy for recurrent pancreatic cancer; reasonable option.
Hagiwara Y +8 more
europepmc +2 more sources
Cancers, 2020 Radiotherapy using accelerated charged particles is rapidly growing worldwide. About 85% of the cancer patients receiving particle therapy is irradiated with protons, which have physical advantages compared to X-rays but similar biological response. In addition to the ballistic advantages, heavy ions present specific radiobiological features that can ...
Tinganelli W., Durante M.
openaire +5 more sources
KAGUYA observation of global emissions of indigenous carbon ions from the Moon. [PDF]
Sci Adv, 2020 KAGUYA observed global emissions of carbon ions from the Moon, which have possibly existed since its birth. Carbon is a volatile element that has a considerable influence on the formation and evolution of planetary bodies, although it was previously ...
Yokota S +10 more
europepmc +2 more sources
Frontiers in Oncology, 2022 The paper begins by emphasizing the clinical and commercial importance of proton or other charged particle such as carbon ion therapy, refers to the manufacturers of such systems of which more than 120 are installed or under construction worldwide by ...
Edward W. Collings +3 more
doaj +1 more source