Results 11 to 20 of about 5,662,469 (305)

Cellular irradiations with laser-driven carbon ions at ultra-high dose rates

Physics in Medicine and Biology, 2023
Objective. Carbon is an ion species of significant radiobiological interest, particularly in view of its use in cancer radiotherapy, where its large Relative Biological Efficiency is often exploited to overcome radio resistance.
P. Chaudhary, G. Milluzzo, A. McIlvenny, H. Ahmed, A. Mcmurray, Carla Maiorino, K. Polin, L. Romagnani, D. Doria, S. McMahon, S. Botchway, P. Rajeev, K. Prise, M. Borghesi   +13 more
semanticscholar   +1 more source

The Effects of Combined Exposure to Simulated Microgravity, Ionizing Radiation, and Cortisol on the In Vitro Wound Healing Process

Cells, 2023
Human spaceflight is associated with several health-related issues as a result of long-term exposure to microgravity, ionizing radiation, and higher levels of psychological stress.
Wilhelmina E. Radstake, Kiran Gautam, Silvana Miranda, Randy Vermeesen, Kevin Tabury, Emil Rehnberg, Jasmine Buset, Ann Janssen, Liselotte Leysen, Mieke Neefs, Mieke Verslegers, Jürgen Claesen, Marc-Jan van Goethem, Uli Weber, Claudia Fournier, Alessio Parisi, Sytze Brandenburg, Marco Durante, Bjorn Baselet, Sarah Baatout   +19 more
doaj   +1 more source

Radioactive Beams for Image-Guided Particle Therapy: The BARB Experiment at GSI

Frontiers in Oncology, 2021
Several techniques are under development for image-guidance in particle therapy. Positron (β+) emission tomography (PET) is in use since many years, because accelerated ions generate positron-emitting isotopes by nuclear fragmentation in the human body ...
Daria Boscolo, Daria Kostyleva, Mohammad Javad Safari, Vasiliki Anagnostatou, Juha Äystö, Juha Äystö, Soumya Bagchi, Tim Binder, Georgios Dedes, Peter Dendooven, Timo Dickel, Timo Dickel, Vasyl Drozd, Vasyl Drozd, Bernhard Franczack, Hans Geissel, Hans Geissel, Chiara Gianoli, Christian Graeff, Tuomas Grahn, Tuomas Grahn, Florian Greiner, Emma Haettner, Roghieh Haghani, Muhsin N. Harakeh, Felix Horst, Christine Hornung, Christine Hornung, Jan-Paul Hucka, Jan-Paul Hucka, Nasser Kalantar-Nayestanaki, Erika Kazantseva, Birgit Kindler, Ronja Knöbel, Natalia Kuzminchuk-Feuerstein, Bettina Lommel, Ivan Mukha, Chiara Nociforo, Shunki Ishikawa, Giulio Lovatti, Munetaka Nitta, Ikechi Ozoemelam, Stephane Pietri, Wolfgang R. Plaß, Wolfgang R. Plaß, Andrej Prochazka, Sivaji Purushothaman, Claire-Anne Reidel, Heidi Roesch, Heidi Roesch, Fabio Schirru, Christoph Schuy, Olga Sokol, Timo Steinsberger, Timo Steinsberger, Yoshiki K. Tanaka, Isao Tanihata, Isao Tanihata, Isao Tanihata, Peter Thirolf, Walter Tinganelli, Bernd Voss, Uli Weber, Helmut Weick, John S. Winfield, Martin Winkler, Jianwei Zhao, Jianwei Zhao, Christoph Scheidenberger, Christoph Scheidenberger, Katia Parodi, Marco Durante, Marco Durante, the Super-FRS Experiment Collaboration   +73 more
doaj   +1 more source

First Human Cell Experiments With FLASH Carbon Ions

Anticancer Research, 2022
Background/Aim: This study aimed to establish a setup for ultra-high-dose-rate (FLASH) carbon-ion irradiation, and to conduct the first human cell experiments using FLASH carbon ions.
M. Tashiro, Y. Yoshida, T. Oike, Masao Nakao, K. Yusa, Yuka Hirota, T. Ohno   +6 more
semanticscholar   +1 more source

Ultra-High Dose-Rate, Pulsed (FLASH) Radiotherapy with Carbon Ions: Generation of Early, Transient, Highly Oxygenated Conditions in the Tumor Environment. [PDF]

Radiat Res, 2020
It is well known that molecular oxygen is a product of the radiolysis of water with high-linear energy transfer (LET) radiation, which is distinct from low-LET radiation wherein O2 radiolytic yield is negligible.
Zakaria AM, Colangelo NW, Meesungnoen J, Azzam EI, Plourde MÉ, Jay-Gerin JP.   +5 more
europepmc   +2 more sources

Application of Carbon Quantum dot Fluorescent Materials in Metal Ions Detection [PDF]

E3S Web of Conferences, 2021
The research situation of the application of carbon quantum dot fluorescent materials to the detection of metal ions, including the current research status and preface of recent years, and development trends are summarized.
Gao Yan, Han Li, Gao Xing, He Wen, Chu Ranran, Ma Yefei   +5 more
doaj   +1 more source

In Vitro Effects of Photon Beam and Carbon Ion Radiotherapy on the Perineural Invasion of Two Cell Lines of Neurotropic Tumours

Life, 2023
Primary mucosal melanoma (PMM) and pancreatic ductal adenocarcinoma (PDAC) are two aggressive malignancies, characterized by intrinsic radio-chemoresistance and neurotropism, a histological feature resulting in frequent perineural invasion (PNI ...
Alexandra Charalampopoulou, Amelia Barcellini, Giuseppe Emanuele Frittitta, Giorgia Fulgini, Giovanni Battista Ivaldi, Giuseppe Magro, Marco Liotta, Ester Orlandi, Marco Giuseppe Pullia, Paola Tabarelli de Fatis, Angelica Facoetti   +10 more
doaj   +1 more source

Factors released by low and high-LET irradiated fibroblasts modulate migration and invasiveness of pancreatic cancer cells

Frontiers in Oncology, 2022
IntroductionRadiotherapy represents a major treatment option for patients with pancreatic cancer, however, its benefits remain limited also due to the ability of cancer cells to migrate to the surrounding tissues. Low-LET ionizing radiation is well known
Alexandra Charalampopoulou, Amelia Barcellini, Mario Ciocca, Riccardo Di Liberto, Francesca Pasi, Marco Giuseppe Pullia, Ester Orlandi, Angelica Facoetti   +7 more
doaj   +1 more source

Monitoring Carbon Ion Beams Transverse Position Detecting Charged Secondary Fragments: Results From Patient Treatment Performed at CNAO

Frontiers in Oncology, 2021
Particle therapy in which deep seated tumours are treated using 12C ions (Carbon Ions RadioTherapy or CIRT) exploits the high conformity in the dose release, the high relative biological effectiveness and low oxygen enhancement ratio of such projectiles.
Marco Toppi, Marco Toppi, Guido Baroni, Giuseppe Battistoni, Maria Giuseppina Bisogni, Maria Giuseppina Bisogni, Piergiorgio Cerello, Mario Ciocca, Patrizia De Maria, Micol De Simoni, Micol De Simoni, Marco Donetti, Yunsheng Dong, Yunsheng Dong, Alessia Embriaco, Veronica Ferrero, Elisa Fiorina, Elisa Fiorina, Marta Fischetti, Marta Fischetti, Gaia Franciosini, Gaia Franciosini, Aafke Christine Kraan, Carmela Luongo, Carmela Luongo, Etesam Malekzadeh, Marco Magi, Carlo Mancini-Terracciano, Carlo Mancini-Terracciano, Michela Marafini, Michela Marafini, Ilaria Mattei, Enrico Mazzoni, Riccardo Mirabelli, Riccardo Mirabelli, Riccardo Mirabelli, Alfredo Mirandola, Matteo Morrocchi, Matteo Morrocchi, Silvia Muraro, Vincenzo Patera, Vincenzo Patera, Vincenzo Patera, Francesco Pennazio, Angelo Schiavi, Angelo Schiavi, Adalberto Sciubba, Adalberto Sciubba, Adalberto Sciubba, Elena Solfaroli-Camillocci, Elena Solfaroli-Camillocci, Elena Solfaroli-Camillocci, Giancarlo Sportelli, Giancarlo Sportelli, Sara Tampellini, Giacomo Traini, Giacomo Traini, Serena Marta Valle, Barbara Vischioni, Viviana Vitolo, Alessio Sarti, Alessio Sarti, Alessio Sarti   +62 more
doaj   +1 more source

Laser Acceleration of Highly Energetic Carbon Ions Using a Double-Layer Target Composed of Slightly Underdense Plasma and Ultrathin Foil. [PDF]

Physical Review Letters, 2018
We report the experimental generation of highly energetic carbon ions up to 48 MeV per nucleon by shooting double-layer targets composed of well-controlled slightly underdense plasma and ultrathin foils with ultraintense femtosecond laser pulses ...
Wenjun Ma, Wenjun Ma, I. J. Kim, J. Q. Yu, I. Choi, P. Singh, H. W. Lee, J. Sung, S. Lee, C. Lin, Q. Liao, J. Zhu, H. Lu, B. Liu, Hongyong Wang, R. Xu, Xian-tu He, J. Chen, M. Zepf, J. Schreiber, J. Schreiber, Xueqing Q. Yan, Xueqing Q. Yan, C. Nam   +23 more
semanticscholar   +1 more source