Results 31 to 40 of about 2,815,789 (303)
Quasi-monoenergetic carbon ions generation from a double-layer target driven by extreme laser pulses
New Journal of Physics, 2023 High quality energetic carbon ions produced via laser-plasma have many applications in tumor therapy, fast ignition and warm dense matter generation. However, the beam achieved in current experiments is still limited by either a large energy spread or a ...
Yuqing Wei +5 more
doaj +1 more source
Carbon ion radiotherapy for sacral chordoma [PDF]
The British Journal of Radiology, 2011 The National Institute of Radiological Sciences in Chiba, Japan has offered carbon ion radiotherapy (CIRT) since 1994 using carbon ion beams generated by the heavy ion medical accelerator in Chiba (HIMAC). The total number of cases treated with the HIMAC exceeded 5000 in July 2009.
R, Imai +4 more
openaire +2 more sources
The Emerging Role of Carbon-Ion Radiotherapy [PDF]
Frontiers in Oncology, 2016 Carbon-ion radiotherapy (CIRT) has progressed rapidly in technological delivery, indications, and efficacy. Owing to a focused dose distribution in addition to high linear energy transfer and subsequently high relative biological effect, CIRT is uniquely able to target otherwise untreatable hypoxic and radioresistant disease while opening the door for ...
Daniel K Ebner +2 more
openaire +3 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Nukleonika, 2016 The area of interests of nuclear physics are studies of reactions, wherein atomic nuclei of projectile collide with target nuclei. An amount of energy lost by projectile nucleus during its passing through the target is a major issue – it is important to ...
Maliszewska Weronika +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Application of polypyrrole multi-walled carbon nanotube composite layer for detection of mercury, lead and iron ions using surface plasmon resonance technique. [PDF]
PLoS ONE, 2014 Polypyrrole multi-walled carbon nanotube composite layers were used to modify the gold layer to measure heavy metal ions using the surface plasmon resonance technique.
Amir Reza Sadrolhosseini +5 more
doaj +1 more source
Disposable electrochemical sensor for the detection of lead(II) ions in the natural water
International Journal of Electrochemical Science, 2021 The leaching of metal ions from the mines may result in pollution of the surrounding waters. In this work, we propose a composite material that combines porous carbon and graphene (G-C), which shows a very high sensitivity to lead ions.
Guojing Fan, Xiaoyan Luo
doaj +1 more source