Results 51 to 60 of about 810,036 (303)

Carbon-ion Radiotherapy for Colorectal Cancer

Journal of the Anus, Rectum and Colon, 2021
Heavy-ion radiotherapy (RT) is a kind of particle RT, and carbon-ion beam constitutes the primary delivery method of heavy-ion RT. Unlike the conventional photon modalities, particle RT, in particular carbon-ion radiotherapy (CIRT), offers unique physical and biological advantages.
Shigeru Yamada, Hirotoshi Takiyama, Yuka Isozaki, Makoto Shinoto, Hirokazu Makishima, Naoyoshi Yamamoto, Hiroshi Tsuji   +6 more
openaire   +4 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Synthesis of Up-Conversion Fluorescence N-Doped Carbon Dots with High Selectivity and Sensitivity for Detection of Cu²⁺ Ions

Crystals, 2023
Carbon dots have drawn extensive attention in the detection of metal ions with good stability, excellent biocompatibility and low toxicity. Meanwhile, the quantum yield, response rate and the detection mechanism for Cu2+ ions are vital to their ...
Yuanyuan Xiong, Mengxiao Chen, Zhen Mao, Yiqing Deng, Jing He, Huaixuan Mu, Peini Li, Wangcai Zou, Qiang Zhao   +8 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Carbon Ion and Proton Beam Irradiation of a Normal Human TK6 Lymphoblastoid Cell Line Within a Magnetic Field of 1.0 Tesla [Corrigendum]

Cancer Management and Research, 2021
Yudhistiara B, Weber KJ, Huber PE, et al. Cancer Manag Res. 2019;11:8327–8335.   The authors have advised the article type shown on page 8327 is incorrect. The text “REVIEW” should read “ORIGINAL RESEARCH”.
Yudhistiara B, Weber KJ, Huber PE, Ruehle A, Brons S, Haering P, Debus J, Hauswald H   +7 more
doaj  

Generation of quasi-monoenergetic protons from thin multi-ion foils by a combination of laser radiation pressure acceleration and shielded Coulomb repulsion [PDF]

, 2013
We study theoretically and numerically the acceleration of protons by a combination of laser radiation pressure acceleration and Coulomb repulsion of carbon ions in a multi-ion thin foil made of carbon and hydrogen.
Chen, Shih-Hung, Eliasson, Bengt, He, Minqing, Liu, Chuan-Sheng, Liu, Tung-Chang, Shao, Xi, Su, Jao-Jang, Tripathi, Vipin, Wang, Jyhpung   +8 more
core   +1 more source

Ion Beam Analyses of Carbon Nanotubes [PDF]

The Journal of Physical Chemistry B, 2005
The utility of ion beam analysis (IBA) techniques to quantitatively determine impurities in carbon nanotubes (CNTs) over a wide range of atomic numbers is demonstrated. Such techniques have not previously been used to monitor impurities and their effects in this unique material. Despite the difficulty in mounting the samples (which generally are formed
Naab, Fabian U., Holland, Orin W., Duggan, Jerome L., McDaniel, Floyd Del. (Floyd Delbert)   +4 more
openaire   +3 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Factors Influencing the Biological Effects of FLASH Irradiation

Antioxidants
Among the methods for increasing the specificity of tumor radiotherapy, FLASH radiotherapy (FLASH-RT) stands out, having recently entered clinical trials.
Sergey Igorevich Glukhov, Elena Ananievna Kuznetsova, Sergey Vsevolodovich Akulinichev   +2 more
doaj   +1 more source

Response of mouse epidermal cells to single doses of heavy-particles [PDF]

, 1972
The survival of mouse epidermal cells to heavy-particles has been studied In Vivo by the Withers clone technique. Experiments with accelerated helium, lithium and carbon ions were performed.
Leith, J. T., Schilling, W. A., Welch, G. P.   +2 more
core   +1 more source