Results 81 to 90 of about 774,901 (354)

The thermodynamic landscape of carbon redox biochemistry [PDF]

, 2018
Redox biochemistry plays a key role in the transduction of chemical energy in all living systems. Observed redox reactions in metabolic networks represent only a minuscule fraction of the space of all possible redox reactions.
Aspuru-Guzik, Alán, Goldford, Joshua, Jinich, Adrian, Noor, Elad, Ren, Haniu, Sanchez-Lengeling, Benjamin, Sanders, Jacob, Segre, Daniel   +7 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Regulation of Symbiotic Nitrogen Fixation in Legume Root Nodules

Plants, 2019
In most legume nodules, the di-nitrogen (N2)-fixing rhizobia are present as organelle-like structures inside their root host cells. Many processes operate and interact within the symbiotic relationship between plants and nodules, including nitrogen (N ...
Andrés R. Schwember, Joachim Schulze, Alejandro del Pozo, Ricardo A. Cabeza   +3 more
doaj   +1 more source

Predicting plankton net community production in the Atlantic Ocean [PDF]

, 2009
We present, test and implement two contrasting models to predict euphotic zone net community production (NCP), which are based on 14C primary production (PO14CP) to NCP relationships over two latitudinal (ca.
Agustí, Anderson, Arístegui, Bender, Berges, Bisset, Blight, Boyd, Burke, Carol Robinson, Cota, Cyr, del Giorgio, del Giorgio, Doney, Duarte, Duarte, Duarte, Emerson, Emerson, Emilio Fernández, Eva Teira, Fasham, Fogg, Gavin Tilstone, González, Gruber, Hairston, Hairston, Hansell, Hansell, Hansell, Hanson, Harris, Jansson, Karl, Karl, Kiddon, Kiørboe, Laws, Legendre, Longhurst, Longhurst, Ludwig, Margalef, McGrady-Steed, McNaughton, Michaels, Najjar, Ono, Pablo Serret, Pace, Peters, Polis, Polis, Pomeroy, Pérez, Quay, Rivkin, Robinson, Robinson, Robinson, Scavia, Schindler, Serret, Serret, Serret, Serret, Serret, Smith, Sokal, Steinberg, Stephens, Strayer, Tamigneaux, Teira, Teira, Teira, Tremblay, Valesca Pérez, Vézina, Wiens, Williams, Williams, Williams, Yamanaka   +85 more
core   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Trace-gas metabolic versatility of the facultative methanotroph Methylocella silvestris [PDF]

, 2014
The climate-active gas methane is generated both by biological processes and by thermogenic decomposition of fossil organic material, which forms methane and short-chain alkanes, principally ethane, propane and butane1, 2. In addition to natural sources,
A Crombie, AR Theisen, B Gilbert, C Anthony, CJ Marx, CM Reddy, D Mackay, EL Johnson, FD Mango, G Etiope, G Etiope, G Etiope, G Etiope, H Barrios, IR McDonald, J Colby, J Heider, J Sambrook, JD Semrau, JG Leahy, K Tamura, KU Hinrichs, MJ Green, MT Rahman, N Hamamura, NA Patel, NV Coleman, NV Coleman, OU Mason, P Guerlava, RB Cooley, SD Prior, SG Osborn, SN Dedysh, T Furuya, T Kotani, T Kotani, VJ Patel, W Ashraf, WS Reeburgh, Y Chen   +40 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Microbial degradation of dimethylsulphide and related C1-sulphur compounds: organisms and pathways controlling fluxes of sulphur in the biosphere [PDF]

, 2010
Dimethylsulphide (DMS) plays a major role in the global sulphur cycle. It has important implications for atmospheric chemistry, climate regulation, and sulphur transport from the marine to the atmospheric and terrestrial environments.
Boden, Rich, Myronova, Natalia, Schäfer, Hendrik   +2 more
core   +1 more source

Evolution of Central Carbon Metabolism [PDF]

Molecular Cell, 2010
Organisms share a common core to their metabolic networks. But what determined this: chance, chemical necessity, or evolutionary optimization? In this issue of Molecular Cell, Noor et al. (2010) provide new evidence for selection of a network with optimal features from a broader set of possibilities.
openaire   +2 more sources

Patatin‐domain‐containing (phospho)lipases under control: Mammalian co‐regulators and pathogenic activation mechanisms

FEBS Open Bio, EarlyView.
Patatin domain‐containing (phospho)lipases are lipid‐hydrolyzing enzymes central to metabolism, membrane remodeling, and signaling. Their activity relies on precise co‐activation mechanisms involving protein–protein interactions and conformational rearrangements.
Noopur Dubey, Lina Riegler‐Berket, Monika Oberer   +2 more
wiley   +1 more source