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Carbon Monoxide Poisoning

New England Journal of Medicine, 2002
Carbon monoxide poisoning is the most common type of accidental poisoning in the United States, accounting for thousands of emergency department visits and some 800 deaths annually. Carbon monoxide, an insidious byproduct of incomplete hydrocarbon combustion, is generated in toxic amounts by internal-combustion engines, fossil-fuel furnaces, and fires.
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Carbon monoxide poisoning

Forensic Science International, 1989
This paper illustrates the remarkable fall of carbon monoxide poisoning due to the abolition of coal gas in the 1970 era and a corresponding decrease in suicide deaths. It enfolds the varying forms of suicide and accident according to age, sex and circumstance.
D.A.L. Bowen   +3 more
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Carbon Monoxide in Sepsis

Antioxidants & Redox Signaling, 2007
Despite modern practices in critical care medicine, sepsis or systemic inflammatory response syndrome remains a leading cause of morbidity and mortality in the intensive care unit. Thus, the need to identify new therapeutic tools for the treatment of sepsis is urgent. In this context, carbon monoxide has become a promising therapeutic molecule that can
Hötzel, Alexander   +4 more
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Carbon Monoxide Toxicity

Journal of Burn Care & Research, 2009
Inhalation injury consists of a multitude of insults, the first of which is the toxic gases inhaled during the combustion of organic and inorganic substances. Significant morbidity and mortality in patients with burn injury occur due to the varying effects of these gases.
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Carbon Monoxide Poisoning

Critical Care Clinics, 2012
Carbon monoxide (CO) poisoning is the leading cause of death as a result of unintentional poisoning in the United States. CO toxicity is the result of a combination of tissue hypoxia-ischemia secondary to carboxyhemoglobin formation and direct CO-mediated damage at a cellular level.
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Life with Carbon Monoxide

Critical Reviews in Biochemistry and Molecular Biology, 2004
This review focuses on how microbes live on CO as a sole source of carbon and energy and with CO by generating carbon monoxide as a metabolic intermediate. The use of CO is a property of organisms that use the Wood-L jungdahl pathway of autotrophic growth.
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Carbon monoxide and hypertension

Journal of Hypertension, 2004
The enzymatic action of heme oxygenase yields carbon monoxide, biliverdin and iron. Carbon monoxide is implicated in many physiological processes, including the regulation of vascular tissue contractility and apoptosis. By stimulating the soluble guanylyl cyclase (sGC)/cGMP pathway and activating K channels in vascular smooth muscle cells (SMCs ...
Joseph Fomusi Ndisang   +2 more
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Pathogenicity of Carbon Monoxide

The American Journal of Forensic Medicine and Pathology, 1997
The effects of carbon monoxide, one of the most commonly encountered toxic agents in forensic practice, have been known for a long time, but the nature of its bonding to the heme prosthetic group of hemoproteins has only recently been elucidated. In addition to reducing the oxygen capacity of the blood and the consequent systemic hypoxia, carbon ...
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Carbon Monoxide Poisoning

2006
Carbon monoxide poisoning. Carbon monoxide poisoning is a frequent and serious intoxication with an important pre-hospital mortality. The diagnosis is made by the association of a context and compatible neurological and cardiac clinical signs. This diagnosis is now eased by home or firefighters detectors. Management is based primarily on the extraction
Daniel Mathieu   +4 more
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Carbon Monoxide and the Pancreas

Current Pharmaceutical Biotechnology, 2012
Carbon monoxide (CO), often referred to as the silent killer, is a colorless, odorless and tasteless gas. It combines with hemoglobin to produce carboxyhemoglobin, which is ineffective for delivering oxygen to animal and human tissues. On the other hand, CO is endogenously produced in the body as a byproduct of heme degradation catalyzed by the heme ...
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