Results 101 to 110 of about 3,108,852 (346)

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang   +9 more
wiley   +1 more source

DOTA‐grafted Cationic Polymers Behaving as Powerful Macromolecular Resistance‐reversal Agents (MRRAs) Combating Against New Delhi Metallo‐β‐lactamase (NDM)‐producing Bacteria

open access: yesAdvanced Science, EarlyView.
Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang   +9 more
wiley   +1 more source

Global Nitrogen Deposition Promotes Carbon Sink Formation in Terrestrial Ecosystems

open access: yesAdvanced Science, EarlyView.
Nitrogen deposition alleviates ecosystem N limitation and enhances carbon sinks. Using 829 observations, we show 36% of deposited N is retained globally (39.15 Tg N yr−1), with distinct NHx and NOy contributions. This retention drives a terrestrial C sink of 0.88 Pg C yr−1 (25.48%), highlighting the importance of pool‐specific C:N stoichiometry ...
Lei Li   +6 more
wiley   +1 more source

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

open access: yesAdvanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu   +9 more
wiley   +1 more source

Potential for Carbon Forest Plantation in Marginal Timber Forests: The Case of Patagonia, Argentina [PDF]

open access: yes
With the advent of the Kyoto Protocol and its recognition of the use of forestry activities and carbon sinks as acceptable tools for addressing the issue of the build-up of atmospheric carbon, the potential role of planted forests as a vehicle for carbon
Sedjo, Roger
core  

Soil Physiochemical Property Variations and Microbial Community Response Patterns Under Continuous Cropping of Tree Peony

open access: yesAgronomy
Continuous cropping can often deteriorate soil quality and reduce crop yield. Soil properties and microbial communities usually play a vital role in maintaining rhizosphere micro-ecosystem sustainability, which is yet to be addressed in continuous peony ...
Hao Pan   +3 more
doaj   +1 more source

A Risk-Based Method For Estimating The Carbon Sequestration Budget For a Mixed Hardwood Forest [PDF]

open access: yes, 2017
Carbon Dioxide (CO2) levels in the atmosphere have risen from approximately 310 ppm in the 1950’s to over 400 ppm as of 2015. This rise in CO2 has likely resulted in the observed warming trend of the earth’s atmosphere in the same time frame, causing ...
Cooper, Erin
core   +2 more sources

Corals and Reef‐Dwelling Fish Regulate Carbon Storage and Cycling Processes in Coral Reef Ecosystems

open access: yesAdvanced Science, EarlyView.
Coral reefs are biodiversity hotspots, yet their role in carbon storage and cycling remains poorly understood. Using field surveys and modeling in the South China Sea, we reveal the overlooked potential of carbon storage in reef ecosystems and how reef fish, corals, and surface sediment jointly shape reef carbon reservoirs.
Yiting Chen   +8 more
wiley   +1 more source

Spatiotemporal dynamics and climatic-anthropogenic drivers of kernel NDVI across China’s subtropical forests

open access: yesTrees, Forests and People
Subtropical forests play a crucial role in global carbon cycling and climate regulation, yet their vegetation dynamics remain highly sensitive to climate variability and anthropogenic pressures.
Rong Yu   +11 more
doaj   +1 more source

How to measure, report and verify soil carbon change to realize the potential of soil carbon sequestration for atmospheric greenhouse gas removal

open access: yesGlobal Change Biology, 2019
There is growing international interest in better managing soils to increase soil organic carbon (SOC) content to contribute to climate change mitigation, to enhance resilience to climate change and to underpin food security, through initiatives such as ...
Pete Smith   +17 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy