Results 61 to 70 of about 1,056,543 (307)

Transcritical Carbon Dioxide Charge-Discharge Energy Storage with Integration of Solar Energy [PDF]

open access: yes, 2019
New and improved energy storage technologies are required to overcome non-dispatchability, which is the main challenge for the successful integration of large shares of renewable energy within energy supply systems.
Becerra Villanueva, José Antonio   +4 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Optimising carbon storage by land-management [PDF]

open access: yes, 2011
As the UK’s largest non-government land-owner, the National Trust is committed to reducing its impact on climate change, recognising the importance of soil organic carbon (SOC), and its need for preservation.
BELL, MADELEINE,JANE
core  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Sieving pore design enables stable and fast alloying chemistry of silicon negative electrodes in Li-ion batteries

open access: yesNature Communications
Ideal silicon negative electrodes for high-energy lithium-ion batteries are expected to feature high capacity, minimal expansion, long lifespan, and fast charging.
Jiaxing He   +14 more
doaj   +1 more source

Enhancing Computational Precision for Lattice Boltzmann Schemes in Porous Media Flows

open access: yesComputation, 2016
We reassess a method for increasing the computational accuracy of lattice Boltzmann schemes by a simple transformation of the distribution function originally proposed by Skordos which was found to give a marginal increase in accuracy in the original ...
Farrel Gray, Edo Boek
doaj   +1 more source

Estimation of biomass density and carbon storage in the forests of Andhra Pradesh, India, with emphasis on their deforestation and degradation conditions [PDF]

open access: yes, 2015
The current study evaluates the growing stock, biomass and carbon content of Andhra Pradesh state’s forest (India) along with its current status of forest degradation and loss.
Lakshmi, P. Mamtha   +1 more
core   +3 more sources

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