Results 81 to 90 of about 401,948 (300)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Does plant community plasticity mediate microbial homeostasis?

Ecology and Evolution, 2020
Microbial homeostasis—constant microbial element ratios along resource gradients—is a core ecological tenet, yet not all systems display homeostasis.
Kate M. Buckeridge, Jennie R. McLaren
doaj   +1 more source

Carbon smart agriculture: An integrated regional approach offers significant potential to increase profit and resource use efficiency, and reduce emissions

, 2021
Climate change is a multifaceted problem impacting social, economic and environmental values. Strategies to reduce climate change impacts require novel and integrated solutions that simultaneously benefit multiple parts of society and minimise potential ...
An-Vo, Duc-Anh, Reardon-Smith, Kate, Mushtaq, Shahbaz, Maraseni, Tek   +3 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Long‐Term Active Rather than Passive Restoration Promotes Soil Organic Carbon Accumulation by Alleviating Microbial Nitrogen Limitation in an Extremely Degraded Alpine Grassland

Advanced Science
Grassland degradation disrupts microbial nutrient cycling, yet the role of nitrogen (N) limitation in regulating soil organic carbon (SOC) dynamics during restoration remains poorly understood.
Jinchao Gong, Feida Sun, Jingjing Wu, Shijie Zhou, Yue Xiu, Linlin Li, Tahmina Kausar, Zhouwen Ma, Jiqiong Zhou, Lin Liu, Yongxing Cui, Jordi Sardans, Josep Peñuelas, Ahmed Elrys, Ji Chen, Yanfu Bai   +15 more
doaj   +1 more source

Temperature sensitivity of soil carbon decomposition [PDF]

, 2013
The world's soils contain three times as much carbon as the atmosphere. Thus, any changes in this carbon pool may affect atmospheric CO₂ levels with implications for climate change.
Erhagen, Björn
core  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Land-Use Change and Carbon Sinks [PDF]

When and if the United States chooses to implement a greenhouse gas reduction program, it will be necessary to decide whether carbon sequestration policies — such as those that promote forestation and discourage deforestation — should be part of the ...
Plantinga, Andrew, Stavins, Robert, Lubowski, Ruben   +2 more
core  

Carbon Farming Initiative review [PDF]

, 2014
SUMMARY The Authority is required by legislation to review the Carbon Farming Initiative (CFI) every three years; this is its first review. The review has benefited from consultations with stakeholders from a range of sectors and the Authority thanks ...
Climate Change Authority
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source