Results 21 to 30 of about 356 (148)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Localization of carbonate platforms in ordovician formations of West-Siberian geosyneclise

open access: yesИзвестия Томского политехнического университета: Инжиниринг георесурсов, 2017
The relevance of the research lies in the need to increase facilities for searching oil and gas fields, one of which is a carbonate platform in the pre-Jurassic formation of West Siberia.
Aleksandr Evgenievich Koveshnikov   +3 more
doaj   +2 more sources

SICILIAN JURASSIC PHYSIOGRAPHY AND GEOLOGIC REALMS (ITALY)

open access: yesRivista Italiana di Paleontologia e Stratigrafia, 2004
Two tectono-sedimentary domains, which were deformed during the Neogene and evolved into two large structural sectors, characterize the Sicilian Jurassic: the Maghrebides and Peloritani.
BENEDETTO ABATE   +2 more
doaj   +1 more source

The role of carbonate factories and sea water chemistry on basin‐wide ramp to high‐relief carbonate platform evolution: Triassic, Nanpanjiang Basin, South China

open access: yesThe Depositional Record, 2022
The end‐Permian extinction and its aftermath altered carbonate factories globally for millions of years, but its impact on platform geometries remains poorly understood.
Daniel J. Lehrmann   +7 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Evolution Model of Miocene Isolated Drowned Carbonate Platforms in Xisha Area, South China Sea: A Case Study of Ganquan Carbonate Platform

open access: yesJournal of Marine Science and Engineering
Isolated drowned carbonate platforms in the Xisha Area represent critical research archives for deciphering the evolutionary mechanisms of carbonate systems and paleoenvironmental changes within the marginal sea of the northern South China Sea ...
Xuelin Li   +5 more
doaj   +1 more source

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