Results 81 to 90 of about 188,803 (283)

Seismic Cycle in Bituminous Dolostones (Monte Camicia Thrust Zone, Central Apennines, Italy)

open access: yesGeochemistry, Geophysics, Geosystems, 2023
Seismic ruptures often propagate along fault zones cutting km‐thick sequences of carbonates (e.g., Wenchuan Mw 7.8, 2008, China; L’Aquila Mw 6.1, 2009, Italy).
Miriana Chinello   +5 more
doaj   +1 more source

Factors affecting metal mobilisation during oxidation of sulphidic, sandy wetland substrates [PDF]

open access: yes, 2010
Most metals accumulate as sulphides under anoxic conditions in wetland substrates, reducing their bioavailability due to the solubility of metal sulphides. However, upon oxidation of these sulphides when the substrate is occasionally oxidised, metals can
A. M. Casas   +27 more
core   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

A Dual Inlet System for Laser Spectroscopy of Triple Oxygen Isotopes in Carbonate‐Derived and Air CO2

open access: yesGeochemistry, Geophysics, Geosystems, 2023
Analyzing the triple oxygen isotope (Δ′17O) composition of carbonates and air CO2 can provide valuable information about Earth system processes. However, accurately measuring the abundance of the rare 17O‐bearing CO2 isotopologue using isotope ratio mass
David Bajnai   +5 more
doaj   +1 more source

Hydrated Double Carbonates - A Raman and Infrared Spectroscopic Study [PDF]

open access: yes, 2007
The Raman spectra of selected double carbonates including pirssonite, gaylussite, shortite and quintinite complemented with infrared spectra have been used to characterise the structure of these carbonate minerals.
Dickfos, Marilla, Frost, Raymond
core   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

COMBINATION OF SALINE SOILS OF THE NORTHERN SLOPE OF THE ERGENI UPLAND AFTER IRRIGATION CESSATION

open access: yesБюллетень Почвенного института им. В.В. Докучаева, 2019
The soil cover and soil salinity of the field were studied and the results are given in the article, the explored fileld is located within the Chervlenoye irrigated area belonging to Svetloyarskaya irrigation system (south of the Volgograd region).
N. B. Khitrov   +2 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy