Results 221 to 230 of about 75,270 (295)

Chromones as Nonclassical Inhibitors of Carbonic Anhydrase IX and XII Isoforms: Probing Chromone-Based Derivatives. [PDF]

Arch Pharm (Weinheim)
Sequeira L, Distinto S, Fernandes C, Sanna E, Meleddu R, Gaspari M, Cottiglia F, Onali A, Angeli A, Borges F, Uriarte E, Alcaro S, Supuran CT, Maccioni E.   +13 more
europepmc   +1 more source

Bile acid metabolism and signaling in human and animal health: A One Health perspective

iMetaOmics, Volume 3, Issue 3, September 2026.
Bile acids maintain host homeostasis through enterohepatic circulation, microbial transformation, and bile acid receptor signaling, thereby regulating glucose and lipid metabolism, intestinal barrier integrity, and immunity. These effects support human disease intervention and health‐oriented animal production, reducing drug dependence and residue ...
Lei Li, Shuai Liu, Zhijun Cao, Yangchun Cao, Shengru Wu, Lu Deng, Junhu Yao, Jun Zhang   +7 more
wiley   +1 more source

A carbonic anhydrase-based nanogel for cyanobacterial growth enhancement. [PDF]

Mater Today Bio
Stoeckle M, Domínguez CM, Hanes A, Weigel S, Kiselev A, Rabe KS, Niemeyer CM.   +6 more
europepmc   +1 more source

Quinoline and Phthalimide Substituted Silicon Phthalocyanines as Multi‐Target Inhibitors of Cholinesterases and Carbonic Anhydrases

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Two novel axially substituted silicon phthalocyanines were synthesized and characterized. Compound 2a exhibited significantly enhanced inhibition of AChE, BChE, hCA I and hCA II, supported by molecular docking and SAR analysis, highlighting its potential as a multifunctional enzyme inhibitor with promising biological activity.
Seda Ünlü, Zeynep Köksal, Kevser Kübra Kırboğa, Fikriye Tuncel Elmalı   +3 more
wiley   +1 more source

Hyaluronic Acid-Palmitate Nanoparticle Delivery of Carbonic Anhydrase Inhibitors Impairs Growth and Early Metabolism in <i>Escherichia coli</i> Through β- and γ-Carbonic Anhydrase-Associated Processes. [PDF]

Int J Mol Sci
De Luca V, Verdoliva V, Supuran CT, De Luca S, Capasso C.   +4 more
europepmc   +1 more source

The Evolution of Medications for Obesity Management

JGH Open, Volume 10, Issue 9, September 2026.
ABSTRACT This narrative review provides an overview of progress in the development of obesity medications, including a synthesis of data describing the efficacy and safety of currently available agents and emerging therapeutic options. Historically, many obesity medications have been withdrawn from the market due to safety concerns.
Jaskirath Gill, Priya Sumithran
wiley   +1 more source

Immobilization and characterization of bovine carbonic anhydrase enzyme on iron oxide magnetic nanoparticles: investigation of potential applicability in CO₂ removal. [PDF]

BMC Chem
Firat M, Beydemir Ş, Işik M, Akpinar Borazan A, Küfrevioğlu Öİ.   +4 more
europepmc   +1 more source

My Love Story With HIFs in the Disc: A Journey to the Humboldt Research Award

JOR SPINE, Volume 9, Issue 3, September 2026.
ABSTRACT The intervertebral disc is a prime example of tissue adaptation to metabolic and mechanical extremes. As the largest avascular organ in the human body, the disc and the central nucleus pulposus (NP) endure constant compressive loading while sustaining a hypoxic, relatively acidic, and hyperosmotic microenvironment that would be inhospitable to
Makarand V. Risbud
wiley   +1 more source

Could carbonic anhydrase IX predict fetal growth restriction in early onset preeclampsia? [PDF]

Rev Assoc Med Bras (1992)
Ozgen G, Dincgez B.
europepmc   +1 more source

Advances in Organic Aggregates for Biomedical Phototheranostics

MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
Organic aggregates offer aggregation‐regulated photophysical properties for biomedical phototheranostics, enabling enhanced fluorescence, stabilized room‐temperature phosphorescence, and efficient photoacoustic/photothermal responses. This review highlights molecular design strategies, excited‐state energy modulation, biomedical applications, and ...
Bowen Fu, Yayun Peng, Ting Cai
wiley   +1 more source