Results 201 to 210 of about 77,334 (297)

Investigating the Inhibitory Properties of Diazo and Pyrazole-Carboxamide-Linked Benzenesulfonamides Against Carbonic Anhydrase Isoforms I, II, IX, and XII. [PDF]

ChemMedChem
Akocak S, Lolak N, Ammara A, Gürbüz G, Bozgeyik I, Taşdemir D, Hashem H, Bräse S, Supuran CT.   +8 more
europepmc   +1 more source

Breath Signatures of Antiseizure Medication Response and Tolerability in Adults With Epilepsy

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Breath metabolomic profiles distinguish treatment response and adverse effects in adults with epilepsy, whereas serum antiseizure medication concentrations do not. These findings support breath analysis as a non‐invasive approach to pharmacodynamic phenotyping, capturing treatment‐related metabolic states relevant to complex human disease.
Kai Fricke, Diego Manuel Baur, Kapil Dev Singh, Felix Schmidt, Kathrin Müsch, Noriane Andrina Sievi, Marco Di Donato, Anton Schmick, Silvia Ulrich, Pablo Sinues, Marian Galovic, Malcolm Kohler   +11 more
wiley   +1 more source

A Novel Strategy for Highly Efficient Heterologous Expression of Carbonic Anhydrase in <i>Yarrowia lipolytica</i>. [PDF]

Int J Mol Sci
Zhao G, Zhu M, Li H, Jiao L, Li Y, Yang K, Wei W, Yang M, Yan Y.   +8 more
europepmc   +1 more source

Association of Urinary pH With Overall Survival in Patients With Stage IV Cancer: A Single‐Center Retrospective Cohort Study

Cancer Nexus, Volume 2, Issue 4, October 2026.
ABSTRACT Objective This single‐center retrospective cohort study evaluated whether, among patients with stage IV cancer who participated in a pragmatic “alkalization therapy”—defined as a low potential renal acid load diet plus oral sodium bicarbonate and/or potassium/sodium citrate—urinary pH was associated with long‐term survival.
Shion Kachi, Kazuyuki Suzuki, Reo Hamaguchi, Ryoko Narui, Hiromasa Morikawa, Hiromi Wada   +5 more
wiley   +1 more source

Expression patterns of carbonic anhydrase IX and immune response biomarkers in pediatric gliomas and glioneuronal tumors. [PDF]

J Neurooncol
Kapitančukė M, Petroška D, Petrosiute A, Lučiūnaitė A, Grincevičienė Š, Matulis D, Ročka S, Raugalas R, Rinkevičius D, Adomaitienė I, Tarutytė G, Rascon J.   +11 more
europepmc   +1 more source

Amyloid‐Forming Amylin Secreted by the Pancreas Promotes Hypoxia‐Inducible Factor Activation and Mitochondrial Alterations in Liver and Heart During Type 2 Diabetes Pathogenesis

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
Human amylin is secreted from the pancreas of HIP rats and is amyloidogenic, forming aggregates systemically. In comparison with age‐matched control (WT), hyperglycemic (UCD) and amylin knockout rats (AKO), HIP rats showed increased hypoxia‐inducible factors (HIF‐1/2) in heart and liver, alongside alterations in mitochondrial electron transfer system ...
Alice E. Knapton, Nirmal Verma, Deepak Kotiya, Alice P. Sowton, Benjamin D. Thackray, Lorenz M. W. Holzner, Paula M. Darwin, Sanda Despa, Florin Despa, Andrew J. Murray   +9 more
wiley   +1 more source

Targeting carbonic anhydrase IX-mediated ferroptosis by atractylenolide I alleviates DSS-induced colitis in mice. [PDF]

Front Pharmacol
Wang Y, Liang M, Guo H, Sun Z, Sun C, Chen M, Xu L.   +6 more
europepmc   +1 more source

Fibromyxoid Nephrogenic Adenoma Mimicking Renal Cell Carcinoma: A Diagnostic Pitfall in Fine‐Needle Aspiration Cytology

Diagnostic Cytopathology, Volume 54, Issue 10, Page E236-E239, October 2026.
ABSTRACT Nephrogenic adenoma (NA) is a benign lesion of the genitourinary tract that may mimic malignancy both clinically and histologically. The fibromyxoid variant (FMNA), characterized by spindled cells in myxoid stroma, presents additional diagnostic challenges due to its rarity and overlapping features with renal cell carcinoma (RCC).
Jodi Gedallovich, Adebola Adeniyi, Ankur R. Sangoi, Xiaohua Qian, Kelly Ernst   +4 more
wiley   +1 more source

Sulfonamide-Based 2-Amino-1,3,4-Oxadiazole Derivatives as Dual Cholinesterase and Carbonic Anhydrase Inhibitors: Design, Synthesis, Kinetic Characterization, Molecular Modeling, and ADMET Evaluation. [PDF]

Drug Dev Res
Arslan Karahan G, Gökçe B, Muhammed MT, Ayan EK, Özçelik AB.   +4 more
europepmc   +1 more source