Results 201 to 210 of about 63,059 (304)

”Not always the magic bullet”—Insufficient seizure control by ketogenic dietary therapies in Glut1 Deficiency Syndrome

Epilepsia Open, Volume 11, Issue 3, Page 847-858, June 2026.
Abstract Objective Ketogenic dietary therapies (KDTs) are the treatment of choice for Glut1 Deficiency Syndrome (Glut1DS), providing dietary ketones as an alternative fuel to the brain and effectively controlling seizures. Recent evidence indicates insufficient seizure control in Glut1DS patients despite adequate KDT and ketosis.
Joerg Klepper, Eva Runkel, Lucia Kiesel
wiley   +1 more source

Aflatoxin B1 Impairs TACE Efficacy Through Downregulated Carbonic Anhydrase 2: A Bioinformatics Analysis. [PDF]

Int J Genomics
Zhang P, Tong Y, Feng X, Lan Q, Wang J.
europepmc   +1 more source

Insights into Carbonic Anhydrase VII functional role

, 2012
DI FIORE, ANNA, C. T. Supuran, DEL GIUDICE, RITA, SANDOMENICO, ANNA MARIA, G. De Simone, MONTI, DARIA MARIA, MONTI, SIMONA MARIA, ARCIELLO, ANGELA, ALTERIO, VINCENZO   +8 more
core  

Renal tubular acidosis: A ‘basic’ disorder

Equine Veterinary Education, Volume 38, Issue 7, Page 365-366, July 2026.
H. J. Mason, L. G. Arroyo
wiley   +1 more source

Glycosyl Coumarins as Selective Inhibitors of Tumor-Associated Carbonic Anhydrase IX and XII: Synthesis, Structure-Activity Relationships, and Molecular Modeling. [PDF]

Int J Mol Sci
Le Pors MS, Aznar I, Giovannuzzi S, Supuran CT, Lavecchia MJ, Colinas PA.   +5 more
europepmc   +1 more source

Interpretable machine learning rationalizes carbonic anhydrase inhibition via conformal and counterfactual prediction. [PDF]

Sci Rep
Ghamsary MS, Rayka M, Naghavi SS.
europepmc   +1 more source

Th17 cells favor migration and invasiveness of cervical cancer cells under hypoxia in an IGF2BP2‐dependent manner

International Journal of Cancer, Volume 158, Issue 11, Page 3021-3037, 1 June 2026.
What's new? Hypoxic regions and inflammatory Th17 cells in the tumor environment are both associated with poor prognosis in cervical cancer. However, synergistic mechanisms between hypoxia and Th17 cells remain elusive. This study demonstrated Th17–hypoxia‐driven mechanisms underlying cervical cancer progression.
Selina Gies, Maike Pohlers, Tanja Tänzer, Emmanuel Ampofo, Matthias W. Laschke, Moritz Schäfer, Yoo‐Jin Kim, Rainer Maria Bohle, Erich‐Franz Solomayer, Konrad Wagner, Martin Empting, Alexandra K. Kiemer, Barbara Walch‐Rückheim   +12 more
wiley   +1 more source

Design and Synthesis of Bis-Triazole-Linked Benzenesulfonamides as Selective Carbonic Anhydrase IX/XII Inhibitors with Chemosensitizing Activity. [PDF]

J Med Chem
Roshdy E, Kilic A, Mustafa M, Celik I, Sarı ZB, Simsek E, Nocentini A, Giovannuzzi S, Supuran CT, Özensoy Güler Ö, Winum JY, Abe M.   +11 more
europepmc   +1 more source

Innovative Drug Delivery Systems for the Treatment of Glaucoma

MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
This review aims to provide a comprehensive overview of current topical drug delivery strategies for ocular hypotensive agents in glaucoma therapy. Additionally, it discusses the potential impact of emerging nanotechnological and biomaterial‐based systems in shaping the future of ophthalmic drug delivery, with an emphasis on enhancing efficacy, safety,
Jing Chu, Junzhi Li, Zhenlin Chen, Jinyu Zhang, Siqi Feng, Jiaying Huang, Yawen Chu, Xue Zhou, Wei Wang, Shangsi Chen   +9 more
wiley   +1 more source

Relationship Between Intraocular Pressure and Carbonic Anhydrase Enzyme Activity in Cattle: Implications for Veterinary Ophthalmology. [PDF]

Vet Med Sci
Yakan S, İşler CT, Genişel M, Yolcu K, Bayat A, Aslan İ.   +5 more
europepmc   +1 more source